6WAQ
Crystal structure of the SARS-CoV-1 RBD bound by the cross-reactive single-domain antibody SARS VHH-72
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C (A, C) | nanobody SARS VHH-72 | polymer | 127 | 13783.0 | 2 | Lama glama | ||
| 2 | B, D (D, B) | Spike glycoprotein | polymer | 191 | 21725.4 | 2 | UniProt (P59594) Pfam (PF09408) | Human SARS coronavirus (SARS-CoV) | S glycoprotein,E2,Peplomer protein |
| 3 | E, F, G (D, B) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 3 | Chemie (NAG) | |||
| 4 | H, I, J, K (A, D, C, B) | water | water | 18.0 | 102 | Chemie (HOH) |
Sequence modifications
D, B: 320 - 502 (UniProt: P59594)
| PDB | External Database | Details |
|---|---|---|
| Gly 503 | - | expression tag |
| Ser 504 | - | expression tag |
| Leu 505 | - | expression tag |
| Glu 506 | - | expression tag |
| Val 507 | - | expression tag |
| Leu 508 | - | expression tag |
| Phe 509 | - | expression tag |
| Gln 510 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 71016.9 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 663.6 | |
| All* | Total formula weight | 71680.6 |
