6VTW

De novo protein design enables the precise induction of RSV-neutralizing antibodies

Summary for 6VTW

Entry DOI	10.2210/pdb6vtw/pdb
Descriptor	S4_2.45, 101F Fab Light Chain, 101F Fab Heavy Chain, ... (4 entities in total)
Functional Keywords	de novo designed, immunogens, antibodies, in vivo, immune system
Biological source	Mus musculus (Mouse) More
Total number of polymer chains	3
Total formula weight	52477.77
Authors	Jardetzky, T.,Correia, B. (deposition date: 2020-02-13, release date: 2020-04-15, Last modification date: 2023-10-11)
Primary citation	Sesterhenn, F.,Yang, C.,Bonet, J.,Cramer, J.T.,Wen, X.,Wang, Y.,Chiang, C.I.,Abriata, L.A.,Kucharska, I.,Castoro, G.,Vollers, S.S.,Galloux, M.,Dheilly, E.,Rosset, S.,Corthesy, P.,Georgeon, S.,Villard, M.,Richard, C.A.,Descamps, D.,Delgado, T.,Oricchio, E.,Rameix-Welti, M.A.,Mas, V.,Ervin, S.,Eleouet, J.F.,Riffault, S.,Bates, J.T.,Julien, J.P.,Li, Y.,Jardetzky, T.,Krey, T.,Correia, B.E. De novo protein design enables the precise induction of RSV-neutralizing antibodies. Science, 368:-, 2020 Cited by PubMed: 32409444 DOI: 10.1126/science.aay5051 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.6 Å)

Structure validation