6WAR

Crystal structure of the MERS-CoV RBD bound by the neutralizing single-domain antibody MERS VHH-55

Summary for 6WAR

Entry DOI	10.2210/pdb6war/pdb
Descriptor	Spike protein, nanobody MERS VHH-55, 2-acetamido-2-deoxy-beta-D-glucopyranose (3 entities in total)
Functional Keywords	mers-cov, nanobody, coronavirus, rbd, viral protein, viral protein-immune system complex, viral protein/immune system
Biological source	Middle East respiratory syndrome-related coronavirus (MERS-CoV) More
Total number of polymer chains	16
Total formula weight	312836.74
Authors	Wrapp, D.,Torres, G.M.,McLellan, J.S. (deposition date: 2020-03-25, release date: 2020-04-08, Last modification date: 2023-10-18)
Primary citation	Wrapp, D.,De Vlieger, D.,Corbett, K.S.,Torres, G.M.,Wang, N.,Van Breedam, W.,Roose, K.,van Schie, L.,Hoffmann, M.,Pohlmann, S.,Graham, B.S.,Callewaert, N.,Schepens, B.,Saelens, X.,McLellan, J.S. Structural Basis for Potent Neutralization of Betacoronaviruses by Single-Domain Camelid Antibodies. Cell, 181:1004-, 2020 Cited by PubMed: 32375025 DOI: 10.1016/j.cell.2020.04.031 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.4 Å)

Structure validation