6WAR
Crystal structure of the MERS-CoV RBD bound by the neutralizing single-domain antibody MERS VHH-55
Summary for 6WAR
Entry DOI | 10.2210/pdb6war/pdb |
Descriptor | Spike protein, nanobody MERS VHH-55, 2-acetamido-2-deoxy-beta-D-glucopyranose (3 entities in total) |
Functional Keywords | mers-cov, nanobody, coronavirus, rbd, viral protein, viral protein-immune system complex, viral protein/immune system |
Biological source | Middle East respiratory syndrome-related coronavirus (MERS-CoV) More |
Total number of polymer chains | 16 |
Total formula weight | 312836.74 |
Authors | Wrapp, D.,Torres, G.M.,McLellan, J.S. (deposition date: 2020-03-25, release date: 2020-04-08, Last modification date: 2023-10-18) |
Primary citation | Wrapp, D.,De Vlieger, D.,Corbett, K.S.,Torres, G.M.,Wang, N.,Van Breedam, W.,Roose, K.,van Schie, L.,Hoffmann, M.,Pohlmann, S.,Graham, B.S.,Callewaert, N.,Schepens, B.,Saelens, X.,McLellan, J.S. Structural Basis for Potent Neutralization of Betacoronaviruses by Single-Domain Camelid Antibodies. Cell, 181:1004-, 2020 Cited by PubMed: 32375025DOI: 10.1016/j.cell.2020.04.031 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.4 Å) |
Structure validation
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