8QPE
| Cryo-EM Structure of Pre-B-like Complex (core part) | 分子名称: | 116 kDa U5 small nuclear ribonucleoprotein component, INOSITOL HEXAKISPHOSPHATE, Microfibrillar-associated protein 1, ... | 著者 | Zhang, Z, Kumar, V, Dybkov, O, Will, C.L, Zhong, J, Ludwig, S, Urlaub, H, Kastner, B, Stark, H, Luehrmann, R. | 登録日 | 2023-10-01 | 公開日 | 2024-05-22 | 最終更新日 | 2024-07-10 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | Structural insights into the cross-exon to cross-intron spliceosome switch. Nature, 630, 2024
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8QO9
| Cryo-EM structure of a human spliceosomal B complex protomer | 分子名称: | 116 kDa U5 small nuclear ribonucleoprotein component, MINX pre-mRNA, Microfibrillar-associated protein 1, ... | 著者 | Zhang, Z, Kumar, V, Dybkov, O, Will, C.L, Urlaub, H, Stark, H, Luehrmann, R. | 登録日 | 2023-09-28 | 公開日 | 2024-01-24 | 最終更新日 | 2024-08-07 | 実験手法 | ELECTRON MICROSCOPY (5.29 Å) | 主引用文献 | Cryo-EM analyses of dimerized spliceosomes provide new insights into the functions of B complex proteins. Embo J., 43, 2024
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8Q7N
| cryo-EM structure of the human spliceosomal B complex protomer (tri-snRNP core region) | 分子名称: | 116 kDa U5 small nuclear ribonucleoprotein component, MINX pre-mRNA, Microfibrillar-associated protein 1, ... | 著者 | Zhang, Z, Kumar, V, Dybkov, O, Will, C.L, Urlaub, H, Stark, H, Luehrmann, R. | 登録日 | 2023-08-16 | 公開日 | 2024-01-24 | 最終更新日 | 2024-08-07 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | Cryo-EM analyses of dimerized spliceosomes provide new insights into the functions of B complex proteins. Embo J., 43, 2024
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1Y8Q
| SUMO E1 ACTIVATING ENZYME SAE1-SAE2-MG-ATP COMPLEX | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Ubiquitin-like 1 activating enzyme E1A, ... | 著者 | Lois, L.M, Lima, C.D. | 登録日 | 2004-12-13 | 公開日 | 2005-01-25 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | 主引用文献 | Structures of the SUMO E1 provide mechanistic insights into SUMO activation and E2 recruitment to E1 Embo J., 24, 2005
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1Z5S
| Crystal structure of a complex between UBC9, SUMO-1, RANGAP1 and NUP358/RANBP2 | 分子名称: | Ran GTPase-activating protein 1, Ran-binding protein 2, Ubiquitin-conjugating enzyme E2 I, ... | 著者 | Reverter, D, Lima, C.D. | 登録日 | 2005-03-19 | 公開日 | 2005-06-07 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (3.01 Å) | 主引用文献 | Insights into E3 ligase activity revealed by a SUMO-RanGAP1-Ubc9-Nup358 complex. Nature, 435, 2005
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1UP1
| UP1, THE TWO RNA-RECOGNITION MOTIF DOMAIN OF HNRNP A1 | 分子名称: | HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN A1 | 著者 | Xu, R.-M, Jokhan, L, Cheng, X, Mayeda, A, Krainer, A.R. | 登録日 | 1997-03-12 | 公開日 | 1997-09-17 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Crystal structure of human UP1, the domain of hnRNP A1 that contains two RNA-recognition motifs. Structure, 5, 1997
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1U1K
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1U1N
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7R5R
| Structure of the human CCAN CENP-A alpha-satellite complex | 分子名称: | Centromere protein C, DNA (171-MER), Histone H2A type 1-C, ... | 著者 | Yatskevich, S, Muir, K.W, Bellini, D, Zhang, Z, Yang, J, Tischer, T, Predin, M, Dendooven, T, McLaughlin, S.H, Barford, D. | 登録日 | 2022-02-11 | 公開日 | 2022-04-27 | 最終更新日 | 2024-07-17 | 実験手法 | ELECTRON MICROSCOPY (2.44 Å) | 主引用文献 | Structure of the human inner kinetochore bound to a centromeric CENP-A nucleosome. Science, 376, 2022
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6SNZ
| Crystal structure of lamin A coil1b tetramer | 分子名称: | GLYCEROL, Prelamin-A/C | 著者 | Lilina, A.V, Chernyatina, A.A, Guzenko, D, Strelkov, S.V. | 登録日 | 2019-08-28 | 公開日 | 2019-10-23 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Lateral A11type tetramerization in lamins. J.Struct.Biol., 209, 2020
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8HNI
| hnRNP A2/B1 RRMs in complex with telomeric DNA | 分子名称: | DNA (5'-D(P*TP*AP*GP*GP*GP*TP*TP*AP*GP*GP*GP*T)-3'), Heterogeneous nuclear ribonucleoproteins A2/B1 | 著者 | Liu, Y, Abula, A, Xiao, H, Guo, H, Li, T, Zheng, L, Chen, B, Nguyen, H, Ji, X. | 登録日 | 2022-12-07 | 公開日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.644 Å) | 主引用文献 | Structural Insight Into hnRNP A2/B1 Homodimerization and DNA Recognition. J.Mol.Biol., 435, 2023
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6SGC
| Rabbit 80S ribosome stalled on a poly(A) tail | 分子名称: | 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S12, ... | 著者 | Chandrasekaran, V, Juszkiewicz, S, Choi, J, Puglisi, J.D, Brown, A, Shao, S, Ramakrishnan, V, Hegde, R.S. | 登録日 | 2019-08-03 | 公開日 | 2019-12-04 | 最終更新日 | 2022-03-30 | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | 主引用文献 | Mechanism of ribosome stalling during translation of a poly(A) tail. Nat.Struct.Mol.Biol., 26, 2019
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7SYN
| Structure of the HCV IRES bound to the 40S ribosomal subunit, head opening. Structure 8(delta dII) | 分子名称: | 18S rRNA, 40S ribosomal protein S2, HCV IRES, ... | 著者 | Brown, Z.P, Abaeva, I.S, De, S, Hellen, C.U.T, Pestova, T.V, Frank, J. | 登録日 | 2021-11-25 | 公開日 | 2022-07-13 | 実験手法 | ELECTRON MICROSCOPY (4 Å) | 主引用文献 | Molecular architecture of 40S initiation complexes on the Hepatitis C virus IRES: from ribosomal attachment to eIF5B-mediated reorientation of initiator tRNA To Be Published
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7SYG
| Structure of the HCV IRES binding to the 40S ribosomal subunit, closed conformation. Structure 1(delta dII) | 分子名称: | 18S rRNA, 40S ribosomal protein S2, 40S ribosomal protein S24, ... | 著者 | Brown, Z.P, Abaeva, I.S, De, S, Hellen, C.U.T, Pestova, T.V, Frank, J. | 登録日 | 2021-11-25 | 公開日 | 2022-07-13 | 最終更新日 | 2024-02-28 | 実験手法 | ELECTRON MICROSCOPY (4.3 Å) | 主引用文献 | Molecular architecture of 40S initiation complexes on the Hepatitis C virus IRES: from ribosomal attachment to eIF5B-mediated reorientation of initiator tRNA To Be Published
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7SYM
| Structure of the HCV IRES bound to the 40S ribosomal subunit, head opening. Structure 7(delta dII) | 分子名称: | 18S rRNA, 40S ribosomal protein S2, 40S ribosomal protein S21, ... | 著者 | Brown, Z.P, Abaeva, I.S, De, S, Hellen, C.U.T, Pestova, T.V, Frank, J. | 登録日 | 2021-11-25 | 公開日 | 2022-07-13 | 最終更新日 | 2024-02-28 | 実験手法 | ELECTRON MICROSCOPY (4.8 Å) | 主引用文献 | Comprehensive structural overview of the HCV IRES-mediated translation initiation pathway To Be Published
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7SYU
| Structure of the delta dII IRES w/o eIF2 48S initiation complex, closed conformation. Structure 13(delta dII) | 分子名称: | 18S rRNA, 40S ribosomal protein S21, 40S ribosomal protein S24, ... | 著者 | Brown, Z.P, Abaeva, I.S, De, S, Hellen, C.U.T, Pestova, T.V, Frank, J. | 登録日 | 2021-11-25 | 公開日 | 2022-07-13 | 最終更新日 | 2024-10-09 | 実験手法 | ELECTRON MICROSCOPY (4.6 Å) | 主引用文献 | Molecular architecture of 40S translation initiation complexes on the hepatitis C virus IRES. Embo J., 41, 2022
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6R8Y
| Cryo-EM structure of NCP-6-4PP(-1)-UV-DDB | 分子名称: | DNA damage-binding protein 1, DNA damage-binding protein 2, Histone H2A type 1-B/E, ... | 著者 | Matsumoto, S, Cavadini, S, Bunker, R.D, Thoma, N.H. | 登録日 | 2019-04-02 | 公開日 | 2019-06-12 | 最終更新日 | 2024-05-22 | 実験手法 | ELECTRON MICROSCOPY (4.3 Å) | 主引用文献 | DNA damage detection in nucleosomes involves DNA register shifting. Nature, 571, 2019
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6R7Q
| Structure of XBP1u-paused ribosome nascent chain complex with Sec61. | 分子名称: | 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S12, ... | 著者 | Shanmuganathan, V, Cheng, J, Braunger, K, Berninghausen, O, Beatrix, B, Beckmann, R. | 登録日 | 2019-03-29 | 公開日 | 2019-07-10 | 最終更新日 | 2024-05-22 | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | 主引用文献 | Structural and mutational analysis of the ribosome-arresting human XBP1u. Elife, 8, 2019
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7SYT
| Structure of the wt IRES w/o eIF2 48S initiation complex, closed conformation. Structure 13(wt) | 分子名称: | 18S rRNA, 40S ribosomal protein S21, 40S ribosomal protein S24, ... | 著者 | Brown, Z.P, Abaeva, I.S, De, S, Hellen, C.U.T, Pestova, T.V, Frank, J. | 登録日 | 2021-11-25 | 公開日 | 2022-07-13 | 最終更新日 | 2023-02-01 | 実験手法 | ELECTRON MICROSCOPY (4.4 Å) | 主引用文献 | Molecular architecture of 40S translation initiation complexes on the hepatitis C virus IRES. Embo J., 41, 2022
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7SYH
| Structure of the HCV IRES binding to the 40S ribosomal subunit, closed conformation. Structure 2(delta dII) | 分子名称: | 18S rRNA, 40S ribosomal protein S21, 40S ribosomal protein S24, ... | 著者 | Brown, Z.P, Abaeva, I.S, De, S, Hellen, C.U.T, Pestova, T.V, Frank, J. | 登録日 | 2021-11-25 | 公開日 | 2022-07-13 | 実験手法 | ELECTRON MICROSCOPY (4.6 Å) | 主引用文献 | Molecular architecture of 40S initiation complexes on the Hepatitis C virus IRES: from ribosomal attachment to eIF5B-mediated reorientation of initiator tRNA To Be Published
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7SYP
| Structure of the wt IRES and 40S ribosome binary complex, open conformation. Structure 10(wt) | 分子名称: | 18S rRNA, HCV IRES, HCV IRES partially loaded mRNA portion, ... | 著者 | Brown, Z.P, Abaeva, I.S, De, S, Hellen, C.U.T, Pestova, T.V, Frank, J. | 登録日 | 2021-11-25 | 公開日 | 2022-07-27 | 最終更新日 | 2022-08-24 | 実験手法 | ELECTRON MICROSCOPY (4 Å) | 主引用文献 | Molecular architecture of 40S translation initiation complexes on the hepatitis C virus IRES. Embo J., 41, 2022
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8I0P
| The cryo-EM structure of human pre-Bact complex | 分子名称: | 116 kDa U5 small nuclear ribonucleoprotein component, BUD13 homolog, Cell division cycle 5-like protein, ... | 著者 | Zhan, X, Lu, Y, Shi, Y. | 登録日 | 2023-01-11 | 公開日 | 2024-07-31 | 最終更新日 | 2024-08-07 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | Molecular basis for the activation of human spliceosome. Nat Commun, 15, 2024
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1HA1
| HNRNP A1 (RBD1,2) FROM HOMO SAPIENS | 分子名称: | HNRNP A1 | 著者 | Shamoo, Y, Krueger, U, Rice, L, Williams, K.R, Steitz, T.A. | 登録日 | 1996-10-30 | 公開日 | 1997-05-15 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | Crystal structure of the two RNA binding domains of human hnRNP A1 at 1.75 A resolution. Nat.Struct.Biol., 4, 1997
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2LLH
| NMR structure of Npm1_c70 | 分子名称: | Nucleophosmin | 著者 | Banci, L, Bertini, I, Brunori, M, Di Matteo, A, Federici, L, Gallo, A, Lo Sterzo, C, Mori, M. | 登録日 | 2011-11-09 | 公開日 | 2012-06-27 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | Structure of Nucleophosmin DNA-binding Domain and Analysis of Its Complex with a G-quadruplex Sequence from the c-MYC Promoter. J.Biol.Chem., 287, 2012
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2MXY
| Solution structure of hnRNP C RRM in complex with 5'-AUUUUUC-3' RNA | 分子名称: | 5'-R(*AP*UP*UP*UP*UP*UP*C)-3', Heterogeneous nuclear ribonucleoproteins C1/C2 | 著者 | Cienikova, Z, Damberger, F.F, Hall, J, Allain, F.H.-T, Maris, C. | 登録日 | 2015-01-19 | 公開日 | 2015-02-25 | 最終更新日 | 2024-05-01 | 実験手法 | SOLUTION NMR | 主引用文献 | Structural and mechanistic insights into poly(uridine) tract recognition by the hnRNP C RNA recognition motif. J.Am.Chem.Soc., 136, 2014
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