7SYN

Structure of the HCV IRES bound to the 40S ribosomal subunit, head opening. Structure 8(delta dII)

Summary for 7SYN

• Entry DOI: 10.2210/pdb7syn/pdb
• EMDB information: 25534
• Descriptor: 18S rRNA, eS8, uS4, ... (37 entities in total)
• Functional Keywords: hcv, ires, 40s, ribosome
• Biological source: Hepatitis C virus (isolate 1); More
• Total number of polymer chains: 36
• Total formula weight: 1389783.22

Authors

Brown, Z.P.,Abaeva, I.S.,De, S.,Hellen, C.U.T.,Pestova, T.V.,Frank, J. (deposition date: 2021-11-25, release date: 2022-07-13)

• Primary citation: Brown, Z.P.,Abaeva, I.S.,De, S.,Hellen, C.U.T.,Pestova, T.V.,Frank, J.; Molecular architecture of 40S initiation complexes on the Hepatitis C virus IRES: from ribosomal attachment to eIF5B-mediated reorientation of initiator tRNA; To Be Published,

Experimental method

ELECTRON MICROSCOPY (4 Å)