7R5R

Structure of the human CCAN CENP-A alpha-satellite complex

Summary for 7R5R

• Entry DOI: 10.2210/pdb7r5r/pdb
• EMDB information: 14334
• Descriptor: Histone H3-like centromeric protein A, Histone H4, Histone H2A type 1-C, ... (7 entities in total)
• Functional Keywords: chromosome, kinetochore, cell division, centromere, cell cycle
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 12
• Total formula weight: 339979.84

Authors

Yatskevich, S.,Muir, K.W.,Bellini, D.,Zhang, Z.,Yang, J.,Tischer, T.,Predin, M.,Dendooven, T.,McLaughlin, S.H.,Barford, D. (deposition date: 2022-02-11, release date: 2022-04-27, Last modification date: 2022-06-01)

• Primary citation: Yatskevich, S.,Muir, K.W.,Bellini, D.,Zhang, Z.,Yang, J.,Tischer, T.,Predin, M.,Dendooven, T.,McLaughlin, S.H.,Barford, D.; Structure of the human inner kinetochore bound to a centromeric CENP-A nucleosome.; Science, 376:844-852, 2022; PubMed: 35420891; DOI: 10.1126/science.abn3810

Experimental method

ELECTRON MICROSCOPY (2.44 Å)