Structure of XBP1u-paused ribosome nascent chain complex with Sec61.

This is a large structure.

Summary for 6R7Q

Related6R6P 6R6G 6R5Q
EMDB information4745
Descriptor40S ribosomal protein S30, 40S ribosomal protein S7, 40S ribosomal protein S8, ... (90 entities in total)
Functional Keywordstranslational pausing, xbp1, upr, ribosome
Biological sourceHomo sapiens (Human)
Total number of polymer chains88
Total molecular weight3256770.89
Shanmuganathan, V.,Cheng, J.,Braunger, K.,Berninghausen, O.,Beatrix, B.,Beckmann, R. (deposition date: 2019-03-29, release date: 2019-07-10)
Primary citation
Shanmuganathan, V.,Schiller, N.,Magoulopoulou, A.,Cheng, J.,Braunger, K.,Cymer, F.,Berninghausen, O.,Beatrix, B.,Kohno, K.,Heijne, G.V.,Beckmann, R.
Structural and mutational analysis of the ribosome-arresting human XBP1u.
Elife, 8:-, 2019
PubMed: 31246176 (PDB entries with the same primary citation)
DOI: 10.7554/eLife.46267
MImport into Mendeley
Experimental method

Structure validation

Ramachandran outliersSidechain outliersRNA backbone 0.1% 1.8% 0.48MetricValuePercentile RanksWorseBetterPercentile relative to all structuresPercentile relative to all EM structures
Download full validation reportDownload
PDB entries from 2020-10-14