Structure of XBP1u-paused ribosome nascent chain complex with SRP.

This is a large structure.

Summary for 6R6G

EMDB information4729 4735
DescriptoreS31, X-box-binding protein 1, P-tRNA, ... (94 entities in total)
Functional Keywordstranslational pausing, xbp1, upr, cotranslational targeting, srp., ribosome
Biological sourceHomo sapiens (Human)
Total number of polymer chains92
Total molecular weight3366388.66
Shanmuganathan, V.,Cheng, J.,Braunger, K.,Berninghausen, O.,Beatrix, B.,Beckmann, R. (deposition date: 2019-03-27, release date: 2019-07-10, Last modification date: 2019-10-30)
Primary citation
Shanmuganathan, V.,Schiller, N.,Magoulopoulou, A.,Cheng, J.,Braunger, K.,Cymer, F.,Berninghausen, O.,Beatrix, B.,Kohno, K.,Heijne, G.V.,Beckmann, R.
Structural and mutational analysis of the ribosome-arresting human XBP1u.
Elife, 8:-, 2019
PubMed: 31246176 (PDB entries with the same primary citation)
DOI: 10.7554/eLife.46267
MImport into Mendeley
Experimental method

Structure validation

ClashscoreRamachandran outliersSidechain outliersRNA backbone6 0.1% 1.2% 0.55MetricValuePercentile RanksWorseBetterPercentile relative to all structuresPercentile relative to all EM structures
Download full validation reportDownload