6R6G

Structure of XBP1u-paused ribosome nascent chain complex with SRP.

This is a large structure.
?

Functional Information from GO Data

ChainGOidnamespacecontents
AE0005829cellular_componentcytosol
AE0005786cellular_componentsignal recognition particle, endoplasmic reticulum targeting
AE0008312molecular_function7S RNA binding
AE0030942molecular_functionendoplasmic reticulum signal peptide binding
AE0045047biological_processprotein targeting to ER
AE0006614biological_processSRP-dependent cotranslational protein targeting to membrane
AB0005829cellular_componentcytosol
AB0005634cellular_componentnucleus
AB0005786cellular_componentsignal recognition particle, endoplasmic reticulum targeting
AB0008312molecular_function7S RNA binding
AB0008144molecular_functiondrug binding
AB0030942molecular_functionendoplasmic reticulum signal peptide binding
AB0019003molecular_functionGDP binding
AB0005525molecular_functionGTP binding
AB0003924molecular_functionGTPase activity
AB0045047biological_processprotein targeting to ER
AB0042493biological_processresponse to drug
AB0006617biological_processSRP-dependent cotranslational protein targeting to membrane, signal sequence recognition
AB0006616biological_processSRP-dependent cotranslational protein targeting to membrane, translocation
AI0005829cellular_componentcytosol
AI0005730cellular_componentnucleolus
AI0005786cellular_componentsignal recognition particle, endoplasmic reticulum targeting
AI0008312molecular_function7S RNA binding
AI0030942molecular_functionendoplasmic reticulum signal peptide binding
AI0005047molecular_functionsignal recognition particle binding
AI0006614biological_processSRP-dependent cotranslational protein targeting to membrane
10005623cellular_componentcell
10005737cellular_componentcytoplasm
10005829cellular_componentcytosol
10005783cellular_componentendoplasmic reticulum
10030176cellular_componentintegral component of endoplasmic reticulum membrane
10005654cellular_componentnucleoplasm
10005634cellular_componentnucleus
10031490molecular_functionchromatin DNA binding
10003677molecular_functionDNA binding
10003700molecular_functionDNA-binding transcription factor activity
10000981molecular_functionDNA-binding transcription factor activity, RNA polymerase II-specific
10001158molecular_functionenhancer sequence-specific DNA binding
10030331molecular_functionestrogen receptor binding
10002020molecular_functionprotease binding
10046982molecular_functionprotein heterodimerization activity
10042803molecular_functionprotein homodimerization activity
10019901molecular_functionprotein kinase binding
10000978molecular_functionRNA polymerase II proximal promoter sequence-specific DNA binding
10000977molecular_functionRNA polymerase II regulatory region sequence-specific DNA binding
10044212molecular_functiontranscription regulatory region DNA binding
10031625molecular_functionubiquitin protein ligase binding
10060612biological_processadipose tissue development
10001525biological_processangiogenesis
10036500biological_processATF6-mediated unfolded protein response
10006914biological_processautophagy
10071230biological_processcellular response to amino acid stimulus
10071498biological_processcellular response to fluid shear stress
10071332biological_processcellular response to fructose stimulus
10042149biological_processcellular response to glucose starvation
10071333biological_processcellular response to glucose stimulus
10032869biological_processcellular response to insulin stimulus
10071353biological_processcellular response to interleukin-4
10071499biological_processcellular response to laminar fluid shear stress
11990830biological_processcellular response to leukemia inhibitory factor
10071222biological_processcellular response to lipopolysaccharide
10031670biological_processcellular response to nutrient
10034599biological_processcellular response to oxidative stress
10071375biological_processcellular response to peptide hormone stimulus
10035924biological_processcellular response to vascular endothelial growth factor stimulus
10035356biological_processcellular triglyceride homeostasis
10042632biological_processcholesterol homeostasis
10030968biological_processendoplasmic reticulum unfolded protein response
10001935biological_processendothelial cell proliferation
10060691biological_processepithelial cell maturation involved in salivary gland development
10031017biological_processexocrine pancreas development
10006633biological_processfatty acid biosynthetic process
10055089biological_processfatty acid homeostasis
10006955biological_processimmune response
10070059biological_processintrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress
10036498biological_processIRE1-mediated unfolded protein response
10001889biological_processliver development
10007517biological_processmuscle organ development
10043066biological_processnegative regulation of apoptotic process
11902236biological_processnegative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway
11900102biological_processnegative regulation of endoplasmic reticulum unfolded protein response
10070373biological_processnegative regulation of ERK1 and ERK2 cascade
10010832biological_processnegative regulation of myotube differentiation
10060394biological_processnegative regulation of pathway-restricted SMAD protein phosphorylation
10000122biological_processnegative regulation of transcription by RNA polymerase II
10030512biological_processnegative regulation of transforming growth factor beta receptor signaling pathway
10048666biological_processneuron development
10006996biological_processorganelle organization
10014065biological_processphosphatidylinositol 3-kinase signaling
10045766biological_processpositive regulation of angiogenesis
10010508biological_processpositive regulation of autophagy
10045579biological_processpositive regulation of B cell differentiation
10030335biological_processpositive regulation of cell migration
10008284biological_processpositive regulation of cell proliferation
11900103biological_processpositive regulation of endoplasmic reticulum unfolded protein response
12000353biological_processpositive regulation of endothelial cell apoptotic process
11903071biological_processpositive regulation of ER-associated ubiquitin-dependent protein catabolic process
10045600biological_processpositive regulation of fat cell differentiation
12000347biological_processpositive regulation of hepatocyte proliferation
10031062biological_processpositive regulation of histone methylation
10002639biological_processpositive regulation of immunoglobulin production
10051024biological_processpositive regulation of immunoglobulin secretion
12000778biological_processpositive regulation of interleukin-6 secretion
11903489biological_processpositive regulation of lactation
10045348biological_processpositive regulation of MHC class II biosynthetic process
11900413biological_processpositive regulation of phospholipid biosynthetic process by positive regulation of transcription from RNA polymerase II promoter
11900100biological_processpositive regulation of plasma cell differentiation
11901985biological_processpositive regulation of protein acetylation
10042307biological_processpositive regulation of protein import into nucleus
10051897biological_processpositive regulation of protein kinase B signaling
10001934biological_processpositive regulation of protein phosphorylation
10045582biological_processpositive regulation of T cell differentiation
10032008biological_processpositive regulation of TOR signaling
10045944biological_processpositive regulation of transcription by RNA polymerase II
11990440biological_processpositive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress
10006990biological_processpositive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response
11904754biological_processpositive regulation of vascular associated smooth muscle cell migration
11904707biological_processpositive regulation of vascular smooth muscle cell proliferation
10035470biological_processpositive regulation of vascular wound healing
10031648biological_processprotein destabilization
10015031biological_processprotein transport
10010506biological_processregulation of autophagy
10001558biological_processregulation of cell growth
10031647biological_processregulation of protein stability
10034976biological_processresponse to endoplasmic reticulum stress
11990418biological_processresponse to insulin-like growth factor stimulus
10055092biological_processsterol homeostasis
10006366biological_processtranscription by RNA polymerase II
10006511biological_processubiquitin-dependent protein catabolic process
10048010biological_processvascular endothelial growth factor receptor signaling pathway
c0022625cellular_componentcytosolic large ribosomal subunit
c0005634cellular_componentnucleus
c0042788cellular_componentpolysomal ribosome
c0014069cellular_componentpostsynaptic density
c0003723molecular_functionRNA binding
c0003735molecular_functionstructural constituent of ribosome
c0061844biological_processantimicrobial humoral immune response mediated by antimicrobial peptide
c0002181biological_processcytoplasmic translation
c0050829biological_processdefense response to Gram-negative bacterium
c0031640biological_processkilling of cells of other organism
I0005840cellular_componentribosome
I0003735molecular_functionstructural constituent of ribosome
I0006412biological_processtranslation
X0005840cellular_componentribosome
X0003735molecular_functionstructural constituent of ribosome
X0006412biological_processtranslation
u0022627cellular_componentcytosolic small ribosomal subunit
u0005634cellular_componentnucleus
u0003735molecular_functionstructural constituent of ribosome
u0030154biological_processcell differentiation
u0006412biological_processtranslation
N0005840cellular_componentribosome
N0003735molecular_functionstructural constituent of ribosome
N0006412biological_processtranslation
z0044297cellular_componentcell body
z0036464cellular_componentcytoplasmic ribonucleoprotein granule
z0022627cellular_componentcytosolic small ribosomal subunit
z0030425cellular_componentdendrite
z0005783cellular_componentendoplasmic reticulum
z0005730cellular_componentnucleolus
z0048471cellular_componentperinuclear region of cytoplasm
z0005844cellular_componentpolysome
z0019901molecular_functionprotein kinase binding
z0003735molecular_functionstructural constituent of ribosome
z0006924biological_processactivation-induced cell death of T cells
z0048821biological_processerythrocyte development
z0000082biological_processG1/S transition of mitotic cell cycle
z0007369biological_processgastrulation
z0042593biological_processglucose homeostasis
z0022605biological_processmammalian oogenesis stage
z0007093biological_processmitotic cell cycle checkpoint
z0043066biological_processnegative regulation of apoptotic process
z0001890biological_processplacenta development
z0043065biological_processpositive regulation of apoptotic process
z0042274biological_processribosomal small subunit biogenesis
z0006364biological_processrRNA processing
z0033077biological_processT cell differentiation in thymus
z0002309biological_processT cell proliferation involved in immune response
z0031929biological_processTOR signaling
z0006412biological_processtranslation
T0005840cellular_componentribosome
T0003735molecular_functionstructural constituent of ribosome
T0006412biological_processtranslation
Z0005840cellular_componentribosome
Z0003735molecular_functionstructural constituent of ribosome
Z0006412biological_processtranslation
JJ0005840cellular_componentribosome
JJ0046872molecular_functionmetal ion binding
JJ0003735molecular_functionstructural constituent of ribosome
JJ0006412biological_processtranslation
AD0005786cellular_componentsignal recognition particle, endoplasmic reticulum targeting
AD0008312molecular_function7S RNA binding
AD0045900biological_processnegative regulation of translational elongation
AD0006614biological_processSRP-dependent cotranslational protein targeting to membrane
AC0005786cellular_componentsignal recognition particle, endoplasmic reticulum targeting
AC0008312molecular_function7S RNA binding
AC0006617biological_processSRP-dependent cotranslational protein targeting to membrane, signal sequence recognition
RR0022627cellular_componentcytosolic small ribosomal subunit
RR0005794cellular_componentGolgi apparatus
RR0003735molecular_functionstructural constituent of ribosome
RR0006412biological_processtranslation
Y0022626cellular_componentcytosolic ribosome
Y0015934cellular_componentlarge ribosomal subunit
Y0005730cellular_componentnucleolus
Y0005654cellular_componentnucleoplasm
Y0048027molecular_functionmRNA 5'-UTR binding
Y0003735molecular_functionstructural constituent of ribosome
Y0071480biological_processcellular response to gamma radiation
Y0006977biological_processDNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
Y1902164biological_processpositive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator
Y1902167biological_processpositive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
Y0045727biological_processpositive regulation of translation
Y1904803biological_processregulation of translation involved in cellular response to UV
Y0042273biological_processribosomal large subunit biogenesis
Y0006364biological_processrRNA processing
Y0006412biological_processtranslation
II0005840cellular_componentribosome
II0003723molecular_functionRNA binding
II0003735molecular_functionstructural constituent of ribosome
II0006412biological_processtranslation
j0005840cellular_componentribosome
j0046872molecular_functionmetal ion binding
j0019843molecular_functionrRNA binding
j0003735molecular_functionstructural constituent of ribosome
j0006412biological_processtranslation
BB0005840cellular_componentribosome
BB0003735molecular_functionstructural constituent of ribosome
BB0006412biological_processtranslation
PP0005840cellular_componentribosome
PP0003735molecular_functionstructural constituent of ribosome
PP0006412biological_processtranslation
i0005840cellular_componentribosome
i0003735molecular_functionstructural constituent of ribosome
i0006412biological_processtranslation
WW0015935cellular_componentsmall ribosomal subunit
WW0003723molecular_functionRNA binding
WW0003735molecular_functionstructural constituent of ribosome
WW0006412biological_processtranslation
C0005840cellular_componentribosome
C0003735molecular_functionstructural constituent of ribosome
C0006412biological_processtranslation
r0005840cellular_componentribosome
r0003735molecular_functionstructural constituent of ribosome
r0006412biological_processtranslation
B0005840cellular_componentribosome
B0003735molecular_functionstructural constituent of ribosome
B0006412biological_processtranslation
E0005840cellular_componentribosome
E0003735molecular_functionstructural constituent of ribosome
E0006412biological_processtranslation
n0005840cellular_componentribosome
n0003735molecular_functionstructural constituent of ribosome
n0006412biological_processtranslation
TT0005840cellular_componentribosome
TT0003735molecular_functionstructural constituent of ribosome
TT0006412biological_processtranslation
FF0022627cellular_componentcytosolic small ribosomal subunit
FF0042788cellular_componentpolysomal ribosome
FF0003735molecular_functionstructural constituent of ribosome
FF0002181biological_processcytoplasmic translation
FF0042274biological_processribosomal small subunit biogenesis
FF0006364biological_processrRNA processing
UU0005840cellular_componentribosome
UU0003735molecular_functionstructural constituent of ribosome
UU1990830biological_processcellular response to leukemia inhibitory factor
UU0006412biological_processtranslation
90005840cellular_componentribosome
90003735molecular_functionstructural constituent of ribosome
90008270molecular_functionzinc ion binding
90006412biological_processtranslation
w0022627cellular_componentcytosolic small ribosomal subunit
w0005783cellular_componentendoplasmic reticulum
w0005743cellular_componentmitochondrial inner membrane
w0005759cellular_componentmitochondrial matrix
w0072686cellular_componentmitotic spindle
w0071159cellular_componentNF-kappaB complex
w0005730cellular_componentnucleolus
w0005844cellular_componentpolysome
w0014069cellular_componentpostsynaptic density
w0032587cellular_componentruffle membrane
w0003906molecular_functionDNA-(apurinic or apyrimidinic site) endonuclease activity
w0004520molecular_functionendodeoxyribonuclease activity
w0030544molecular_functionHsp70 protein binding
w0051879molecular_functionHsp90 protein binding
w0008017molecular_functionmicrotubule binding
w0003729molecular_functionmRNA binding
w0032357molecular_functionoxidized purine DNA binding
w0032358molecular_functionoxidized pyrimidine DNA binding
w0051018molecular_functionprotein kinase A binding
w0019901molecular_functionprotein kinase binding
w0044877molecular_functionprotein-containing complex binding
w0000977molecular_functionRNA polymerase II regulatory region sequence-specific DNA binding
w0070181molecular_functionsmall ribosomal subunit rRNA binding
w0003735molecular_functionstructural constituent of ribosome
w0097100molecular_functionsupercoiled DNA binding
w0008134molecular_functiontranscription factor binding
w0044390molecular_functionubiquitin-like protein conjugating enzyme binding
w0070301biological_processcellular response to hydrogen peroxide
w0071356biological_processcellular response to tumor necrosis factor
w0007059biological_processchromosome segregation
w0042769biological_processDNA damage response, detection of DNA damage
w0045738biological_processnegative regulation of DNA repair
w0031397biological_processnegative regulation of protein ubiquitination
w0017148biological_processnegative regulation of translation
w0042104biological_processpositive regulation of activated T cell proliferation
w1905053biological_processpositive regulation of base-excision repair
w2001272biological_processpositive regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis
w1902546biological_processpositive regulation of DNA N-glycosylase activity
w0032079biological_processpositive regulation of endodeoxyribonuclease activity
w0010628biological_processpositive regulation of gene expression
w0032743biological_processpositive regulation of interleukin-2 production
w1902231biological_processpositive regulation of intrinsic apoptotic signaling pathway in response to DNA damage
w0043507biological_processpositive regulation of JUN kinase activity
w0031116biological_processpositive regulation of microtubule polymerization
w0051092biological_processpositive regulation of NF-kappaB transcription factor activity
w1901224biological_processpositive regulation of NIK/NF-kappaB signaling
w0050862biological_processpositive regulation of T cell receptor signaling pathway
w0061481biological_processresponse to TNF agonist
w0051225biological_processspindle assembly
w0006412biological_processtranslation
g0005840cellular_componentribosome
g0003735molecular_functionstructural constituent of ribosome
g0006412biological_processtranslation
VV0015935cellular_componentsmall ribosomal subunit
VV0003735molecular_functionstructural constituent of ribosome
VV0006412biological_processtranslation
J0005840cellular_componentribosome
J0003735molecular_functionstructural constituent of ribosome
J0006412biological_processtranslation
KK0005840cellular_componentribosome
KK0003735molecular_functionstructural constituent of ribosome
KK0006412biological_processtranslation
EE0022627cellular_componentcytosolic small ribosomal subunit
EE0003735molecular_functionstructural constituent of ribosome
EE0006412biological_processtranslation
h0005840cellular_componentribosome
h0003735molecular_functionstructural constituent of ribosome
h0006412biological_processtranslation
f0005840cellular_componentribosome
f0003735molecular_functionstructural constituent of ribosome
f0006412biological_processtranslation
AA0005840cellular_componentribosome
AA0003735molecular_functionstructural constituent of ribosome
AA0006412biological_processtranslation
P0015934cellular_componentlarge ribosomal subunit
P0003735molecular_functionstructural constituent of ribosome
P0006412biological_processtranslation
l0005840cellular_componentribosome
l0003735molecular_functionstructural constituent of ribosome
l0006412biological_processtranslation
CC0005840cellular_componentribosome
CC0003735molecular_functionstructural constituent of ribosome
CC0006412biological_processtranslation
W0022625cellular_componentcytosolic large ribosomal subunit
W0005783cellular_componentendoplasmic reticulum
W0042788cellular_componentpolysomal ribosome
W0002181biological_processcytoplasmic translation
A0015934cellular_componentlarge ribosomal subunit
A0003723molecular_functionRNA binding
A0003735molecular_functionstructural constituent of ribosome
A0006412biological_processtranslation
b0005840cellular_componentribosome
b0003735molecular_functionstructural constituent of ribosome
b0006412biological_processtranslation
x0005840cellular_componentribosome
x0019843molecular_functionrRNA binding
x0003735molecular_functionstructural constituent of ribosome
x0006412biological_processtranslation
M0005840cellular_componentribosome
M0003723molecular_functionRNA binding
M0003735molecular_functionstructural constituent of ribosome
M0006412biological_processtranslation
D0005840cellular_componentribosome
D0008097molecular_function5S rRNA binding
D0003735molecular_functionstructural constituent of ribosome
D0006412biological_processtranslation
F0022625cellular_componentcytosolic large ribosomal subunit
F0003735molecular_functionstructural constituent of ribosome
F0000463biological_processmaturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
H0005840cellular_componentribosome
H0019843molecular_functionrRNA binding
H0003735molecular_functionstructural constituent of ribosome
H0006412biological_processtranslation
e0005840cellular_componentribosome
e0003735molecular_functionstructural constituent of ribosome
e0006412biological_processtranslation
a0015934cellular_componentlarge ribosomal subunit
a0003735molecular_functionstructural constituent of ribosome
a0006412biological_processtranslation
y0015935cellular_componentsmall ribosomal subunit
y0003723molecular_functionRNA binding
y0003735molecular_functionstructural constituent of ribosome
y0006412biological_processtranslation
d0005840cellular_componentribosome
d0003735molecular_functionstructural constituent of ribosome
d0006412biological_processtranslation
p0005840cellular_componentribosome
p0003735molecular_functionstructural constituent of ribosome
p0006412biological_processtranslation
QQ0005840cellular_componentribosome
QQ0003735molecular_functionstructural constituent of ribosome
QQ0006412biological_processtranslation
V0005840cellular_componentribosome
V0003735molecular_functionstructural constituent of ribosome
V0006412biological_processtranslation
00005840cellular_componentribosome
00003735molecular_functionstructural constituent of ribosome
00006412biological_processtranslation
DD0015935cellular_componentsmall ribosomal subunit
DD0019843molecular_functionrRNA binding
DD0003735molecular_functionstructural constituent of ribosome
DD0006412biological_processtranslation
o0005840cellular_componentribosome
o0003735molecular_functionstructural constituent of ribosome
o0006412biological_processtranslation
Q0005840cellular_componentribosome
Q0003735molecular_functionstructural constituent of ribosome
Q0006412biological_processtranslation
L0005840cellular_componentribosome
L0003735molecular_functionstructural constituent of ribosome
L0006412biological_processtranslation
s0005840cellular_componentribosome
s0042254biological_processribosome biogenesis
t0005840cellular_componentribosome
t0003735molecular_functionstructural constituent of ribosome
t0006412biological_processtranslation
?

Functional Information from PDB Data

site_idNumber of ResiduesDetails
AC12binding site for residue MG 5 3601
ChainResidue
5G350
CGLY99

AC21binding site for residue MG 5 3602
ChainResidue
5U2613

AC34binding site for residue MG 5 3603
ChainResidue
5U37
5A38
5G40
5C41

AC44binding site for residue MG 5 3604
ChainResidue
5U43
5A44
5U45
NLYS83

AC54binding site for residue MG 5 3605
ChainResidue
5A47
5G48
5U96
5U285

AC62binding site for residue MG 5 3606
ChainResidue
5A51
5G52

AC71binding site for residue MG 5 3607
ChainResidue
5A56

AC81binding site for residue MG 5 3608
ChainResidue
5A61

AC92binding site for residue MG 5 3609
ChainResidue
5A62
5U327

AD14binding site for residue MG 5 3610
ChainResidue
5C83
5A84
5G85
5C942

AD21binding site for residue MG 5 3611
ChainResidue
5A101

AD32binding site for residue MG 5 3612
ChainResidue
5A105
5A106

AD44binding site for residue MG 5 3613
ChainResidue
5C112
5G154
5C155
5G156

AD51binding site for residue MG 5 3614
ChainResidue
5A113

AD61binding site for residue MG 5 3615
ChainResidue
5G235

AD71binding site for residue MG 5 3616
ChainResidue
5A229

AD82binding site for residue MG 5 3617
ChainResidue
5C204
5U225

AD92binding site for residue MG 5 3618
ChainResidue
5C276
5A294

AE12binding site for residue MG 5 3619
ChainResidue
5G282
5A2748

AE21binding site for residue MG 5 3620
ChainResidue
5U285

AE32binding site for residue MG 5 3621
ChainResidue
5A47
5U285

AE42binding site for residue MG 5 3622
ChainResidue
5U2923
5U2924

AE52binding site for residue MG 5 3624
ChainResidue
5C344
5C345

AE62binding site for residue MG 5 3625
ChainResidue
5G350
5A353

AE72binding site for residue MG 5 3626
ChainResidue
5A1725
5MG3727

AE82binding site for residue MG 5 3627
ChainResidue
5G1723
5G1724

AE94binding site for residue MG 5 3628
ChainResidue
5A404
5G409
5U410
5G1724

AF14binding site for residue MG 5 3629
ChainResidue
5C408
5G409
5U410
5G411

AF24binding site for residue MG 5 3630
ChainResidue
5G417
5U418
8G10
8C11

AF33binding site for residue MG 5 3632
ChainResidue
5C1225
5A1672
5G1673

AF43binding site for residue MG 5 3633
ChainResidue
5A1675
aHIS14
eARG39

AF51binding site for residue MG 5 3634
ChainResidue
5A1760

AF61binding site for residue MG 5 3635
ChainResidue
5A1763

AF72binding site for residue MG 5 3636
ChainResidue
5U1762
5C1786

AF82binding site for residue MG 5 3637
ChainResidue
5A1794
5C2178

AF94binding site for residue MG 5 3638
ChainResidue
5U1802
5C1803
5C1804
5A1821

AG12binding site for residue MG 5 3639
ChainResidue
5C1815
5A1816

AG22binding site for residue MG 5 3640
ChainResidue
5C1839
5G1903

AG32binding site for residue MG 5 3641
ChainResidue
5G1907
5G1909

AG41binding site for residue MG 5 3642
ChainResidue
5G2070

AG53binding site for residue MG 5 3643
ChainResidue
5G1795
5A2176
5C2177

AG63binding site for residue MG 5 3644
ChainResidue
5U2181
5A2182
5U2221

AG72binding site for residue MG 5 3645
ChainResidue
5C2185
lLYS48

AG83binding site for residue MG 5 3646
ChainResidue
5G1159
5A1160
5C2187

AG92binding site for residue MG 5 3647
ChainResidue
5A2238
5G2537

AH11binding site for residue MG 5 3648
ChainResidue
5A2250

AH21binding site for residue MG 5 3649
ChainResidue
5A2327

AH32binding site for residue MG 5 3650
ChainResidue
5C2330
5C2480

AH41binding site for residue MG 5 3651
ChainResidue
5C2334

AH52binding site for residue MG 5 3652
ChainResidue
5A2340
5U2343

AH64binding site for residue MG 5 3653
ChainResidue
5C2399
5U2402
5G2403
5U2443

AH73binding site for residue MG 5 3654
ChainResidue
5G2387
5A2446
5U2516

AH81binding site for residue MG 5 3656
ChainResidue
5U2476

AH91binding site for residue MG 5 3657
ChainResidue
5A2481

AI12binding site for residue MG 5 3658
ChainResidue
5U2395
5A2515

AI23binding site for residue MG 5 3659
ChainResidue
5A1756
5U2551
5A2592

AI34binding site for residue MG 5 3660
ChainResidue
5A885
5C886
5A2575
5G2577

AI41binding site for residue MG 5 3661
ChainResidue
5C1238

AI52binding site for residue MG 5 3662
ChainResidue
5C2763
5U2764

AI65binding site for residue MG 5 3663
ChainResidue
5G40
5C41
5U2613
5G2614
5U2759

AI71binding site for residue MG 5 3664
ChainResidue
5A2615

AI81binding site for residue MG 5 3665
ChainResidue
5G2753

AI92binding site for residue MG 5 3666
ChainResidue
5U2618
5G2754

AJ12binding site for residue MG 5 3667
ChainResidue
5A2621
5C2622

AJ22binding site for residue MG 5 3668
ChainResidue
5U35
5U2758

AJ31binding site for residue MG 5 3669
ChainResidue
5U1272

AJ42binding site for residue MG 5 3670
ChainResidue
5A2784
5C2785

AJ54binding site for residue MG 5 3671
ChainResidue
5G2805
5G2806
5G2853
5C2902

AJ62binding site for residue MG 5 3672
ChainResidue
5A2809
DASP29

AJ71binding site for residue MG 5 3673
ChainResidue
5A2851

AJ81binding site for residue MG 5 3675
ChainResidue
5C2956

AJ93binding site for residue MG 5 3676
ChainResidue
5G1193
5G1201
5G3104

AK14binding site for residue MG 5 3677
ChainResidue
5A1192
5G1193
5A3105
AALA203

AK21binding site for residue MG 5 3678
ChainResidue
5A3103

AK31binding site for residue MG 5 3679
ChainResidue
5G3018

AK46binding site for residue MG 5 3680
ChainResidue
5G2963
5A2964
5U2965
5C3013
5C3014
5U3015

AK54binding site for residue MG 5 3681
ChainResidue
5U880
5G882
5A2964
5U3015

AK61binding site for residue MG 5 3683
ChainResidue
5C2987

AK72binding site for residue MG 5 3684
ChainResidue
5A1408
5C3014

AK82binding site for residue MG 5 3685
ChainResidue
5A2600
5G3021

AK92binding site for residue MG 5 3686
ChainResidue
5G2602
5G3021

AL11binding site for residue MG 5 3687
ChainResidue
5A3049

AL23binding site for residue MG 5 3688
ChainResidue
5G2244
5U2245
5A3066

AL34binding site for residue MG 5 3689
ChainResidue
5A2243
5G2244
5U2245
5A3066

AL43binding site for residue MG 5 3690
ChainResidue
5C2531
5A3066
5U3067

AL52binding site for residue MG 5 3691
ChainResidue
5G3021
5G3092

AL63binding site for residue MG 5 3692
ChainResidue
5C3089
5G3090
5U3091

AL72binding site for residue MG 5 3694
ChainResidue
5A3034
5C3056

AL84binding site for residue MG 5 3695
ChainResidue
5G2596
5U3091
5G3092
5A3093

AL92binding site for residue MG 5 3696
ChainResidue
5G1152
5U3096

AM13binding site for residue MG 5 3697
ChainResidue
5G3097
5G3098
5G3099

AM22binding site for residue MG 5 3698
ChainResidue
5G2513
5G3108

AM32binding site for residue MG 5 3699
ChainResidue
5U1151
5G1152

AM42binding site for residue MG 5 3700
ChainResidue
5G1155
5U3128

AM52binding site for residue MG 5 3701
ChainResidue
5U3252
5A3277

AM62binding site for residue MG 5 3702
ChainResidue
5A3275
5G3276

AM71binding site for residue MG 5 3703
ChainResidue
5C3268

AM81binding site for residue MG 5 3704
ChainResidue
5G3220

AM92binding site for residue MG 5 3705
ChainResidue
5U3315
5U3427

AN12binding site for residue MG 5 3706
ChainResidue
5G1432
5A1433

AN21binding site for residue MG 5 3707
ChainResidue
5U1216

AN32binding site for residue MG 5 3708
ChainResidue
5G1240
5G1390

AN42binding site for residue MG 5 3709
ChainResidue
5U1219
aLYS24

AN54binding site for residue MG 5 3710
ChainResidue
5U315
5C316
5G2925
5G2926

AN63binding site for residue MG 5 3711
ChainResidue
5G409
5G411
5MG3714

AN73binding site for residue MG 5 3712
ChainResidue
5U348
5A372
5MG3726

AN85binding site for residue MG 5 3713
ChainResidue
5A347
5U348
5A372
5G373
5MG3726

AN93binding site for residue MG 5 3714
ChainResidue
5G409
5U410
5MG3711

AO11binding site for residue MG 5 3715
ChainResidue
5G896

AO22binding site for residue MG 5 3716
ChainResidue
5G890
5A2563

AO31binding site for residue MG 5 3717
ChainResidue
5G2578

AO41binding site for residue MG 5 3718
ChainResidue
5G2597

AO52binding site for residue MG 5 3719
ChainResidue
5A1756
5G1757

AO62binding site for residue MG 5 3721
ChainResidue
5U1386
LASN6

AO74binding site for residue MG 5 3722
ChainResidue
5G2475
5G2513
5A2514
5U2516

AO83binding site for residue MG 5 3723
ChainResidue
5A2604
5G2605
5G3018

AO91binding site for residue MG 5 3724
ChainResidue
5A2180

AP14binding site for residue MG 5 3725
ChainResidue
5U2219
5G2220
5U2222
5G2223

AP25binding site for residue MG 5 3726
ChainResidue
5A347
5U348
5A372
5MG3712
5MG3713

AP33binding site for residue MG 5 3727
ChainResidue
5G376
5A1725
5MG3626

AP44binding site for residue MG 5 3728
ChainResidue
5G1086
5G1185
5A2615
5G2616

AP53binding site for residue MG 5 3729
ChainResidue
5G1214
5A1239
5U2612

AP63binding site for residue MG 5 3730
ChainResidue
5G1391
5G1392
bLYS5

AP71binding site for residue MG 5 3731
ChainResidue
5A1274

AP81binding site for residue MG 5 3732
ChainResidue
5U2976

AP91binding site for residue MG 5 3733
ChainResidue
5C3282

AQ11binding site for residue MG 5 3734
ChainResidue
5G1241

AQ22binding site for residue MG 5 3735
ChainResidue
5G1076
5A1078

AQ31binding site for residue MG 5 3736
ChainResidue
5U909

AQ41binding site for residue MG 5 3737
ChainResidue
5C1081

AQ52binding site for residue MG 5 3738
ChainResidue
5A1083
5G1211

AQ64binding site for residue MG 5 3739
ChainResidue
5U878
5A883
5A884
eASP42

AQ73binding site for residue MG 5 3740
ChainResidue
5U1148
5U2343
5A2344

AQ81binding site for residue MG 5 3741
ChainResidue
5A2955

AQ93binding site for residue MG 5 3742
ChainResidue
5G2605
5A2606
5A2960

AR12binding site for residue MG 5 3743
ChainResidue
5A1227
5G1673

AR21binding site for residue MG 5 3744
ChainResidue
5G1741

AR33binding site for residue MG 5 3745
ChainResidue
5U1442
5U1443
5C1603

AR41binding site for residue MG 5 3746
ChainResidue
5G1671

AR52binding site for residue MG 5 3747
ChainResidue
5C14
5A15

AR62binding site for residue MG 5 3748
ChainResidue
5U878
5G1217

AR71binding site for residue MG 5 3749
ChainResidue
5C3131

AR82binding site for residue MG 5 3750
ChainResidue
5C1416
5U1419

AR91binding site for residue MG 5 3751
ChainResidue
5G1417

AS11binding site for residue MG 5 3753
ChainResidue
5C927

AS22binding site for residue MG 5 3754
ChainResidue
5U236
5A237

AS32binding site for residue MG 5 3755
ChainResidue
5G235
5U236

AS41binding site for residue MG 5 3756
ChainResidue
5G231

AS51binding site for residue MG 5 3758
ChainResidue
5G1134

AS61binding site for residue MG 5 3759
ChainResidue
5U1098

AS73binding site for residue MG 5 3760
ChainResidue
5A1093
5A1094
5U1180

AS82binding site for residue MG 5 3761
ChainResidue
5G2145
5G2147

AS92binding site for residue MG 5 3762
ChainResidue
5G48
5C283

AT12binding site for residue MG 5 3763
ChainResidue
5G48
5C283

AT21binding site for residue MG 5 3764
ChainResidue
5A65

AT33binding site for residue MG 5 3765
ChainResidue
5A322
5A323
5G324

AT42binding site for residue MG 5 3766
ChainResidue
5G58
8C35

AT51binding site for residue MG 5 3767
ChainResidue
5A101

AT63binding site for residue MG 5 3768
ChainResidue
5C92
5G93
5U2910

AT72binding site for residue MG 5 3770
ChainResidue
5A887
5C888

AT84binding site for residue MG 5 3771
ChainResidue
5C1235
5C1236
5G2947
5A2948

AT94binding site for residue MG 5 3772
ChainResidue
5G1424
5A1425
5U1426
5C1475

AU11binding site for residue MG 5 3773
ChainResidue
5C1452

AU21binding site for residue MG 5 3774
ChainResidue
5G872

AU32binding site for residue MG 5 3775
ChainResidue
5G2579
5C2580

AU41binding site for residue MG 5 3776
ChainResidue
5G1612

AU51binding site for residue MG 5 3778
ChainResidue
5G2367

AU63binding site for residue MG 5 3779
ChainResidue
5U2032
5G2033
5G2081

AU72binding site for residue MG 5 3780
ChainResidue
5A2089
5A2090

AU84binding site for residue MG 5 3782
ChainResidue
5G1836
5A1904
5G1907
5G1908

AU93binding site for residue MG 5 3783
ChainResidue
5A1846
5C1858
5G1859

AV14binding site for residue MG 5 3784
ChainResidue
5G2752
5G2753
5G2754
5G2755

AV22binding site for residue MG 5 3785
ChainResidue
5A2238
5G2239

AV32binding site for residue MG 5 3786
ChainResidue
5C3232
5G3233

AV41binding site for residue MG 5 3787
ChainResidue
5C2556

AV52binding site for residue MG 5 3788
ChainResidue
5C1140
5C1170

AV63binding site for residue MG 5 3789
ChainResidue
5U1138
5C1139
5C1170

AV71binding site for residue MG 5 3790
ChainResidue
5G3201

AV82binding site for residue MG 5 3791
ChainResidue
5G3201
5U3202

AV93binding site for residue MG 5 3795
ChainResidue
5C1431
5G1432
7A83

AW12binding site for residue MG 5 3796
ChainResidue
5U1705
8A9

AW22binding site for residue MG 5 3797
ChainResidue
5U1686
8A20

AW31binding site for residue MG 5 3798
ChainResidue
5A1242

AW42binding site for residue MG 5 3799
ChainResidue
5G1249
QASN8

AW54binding site for residue MG 5 3800
ChainResidue
5A1387
5G1676
5G1677
aGLY18

AW63binding site for residue MG 5 3801
ChainResidue
5C1418
eILE41
eASP42

AW74binding site for residue MG 5 3802
ChainResidue
5G1977
gGLY55
gTHR70
gHIS73

AW81binding site for residue MG 7 201
ChainResidue
7U120

AW92binding site for residue MG 7 203
ChainResidue
7G41
7A42

AX12binding site for residue MG 7 204
ChainResidue
7A54
7A55

AX23binding site for residue MG 7 205
ChainResidue
7U53
7A55
7G56

AX31binding site for residue MG 7 206
ChainResidue
7G65

AX43binding site for residue MG 8 201
ChainResidue
5U1837
5G1903
8U110

AX51binding site for residue MG 8 202
ChainResidue
8A65

AX62binding site for residue MG 8 203
ChainResidue
8U51
8A52

AX72binding site for residue MG 8 204
ChainResidue
8G68
8U69

AX82binding site for residue MG A 301
ChainResidue
AASN194
APRO197

AX93binding site for residue MG B 501
ChainResidue
5U3197
5A3235
BLYS373

AY13binding site for residue MG I 300
ChainResidue
5G1401
5G1402
IASN14

AY21binding site for residue MG K 1901
ChainResidue
KA11

AY31binding site for residue MG K 1902
ChainResidue
KG16

AY42binding site for residue MG K 1904
ChainResidue
KA27
KU28

AY52binding site for residue MG K 1905
ChainResidue
KC48
KA473

AY61binding site for residue MG K 1906
ChainResidue
KC472

AY72binding site for residue MG K 1907
ChainResidue
KG94
KG95

AY83binding site for residue MG K 1909
ChainResidue
KU100
KU406
KG407

AY94binding site for residue MG K 1910
ChainResidue
EELYS98
KG420
KG421
KC660

AZ12binding site for residue MG K 1911
ChainResidue
KA508
KG509

AZ22binding site for residue MG K 1912
ChainResidue
KG434
KC450

AZ32binding site for residue MG K 1913
ChainResidue
KA449
KC450

AZ43binding site for residue MG K 1914
ChainResidue
KA523
KC593
KA594

AZ52binding site for residue MG K 1915
ChainResidue
KG602
KC603

AZ61binding site for residue MG K 1916
ChainResidue
KA653

AZ73binding site for residue MG K 1917
ChainResidue
KG419
KA654
KG656

AZ83binding site for residue MG K 1918
ChainResidue
KC663
KC1153
KG1157

AZ94binding site for residue MG K 1919
ChainResidue
KU667
KA668
KA669
KA670

BC12binding site for residue MG K 1920
ChainResidue
KA668
KA1087

BC21binding site for residue MG K 1921
ChainResidue
KG1167

BC34binding site for residue MG K 1922
ChainResidue
KA671
KA672
KG673
KC674

BC41binding site for residue MG K 1923
ChainResidue
KA1082

BC52binding site for residue MG K 1924
ChainResidue
KC676
KU1025

BC63binding site for residue MG K 1925
ChainResidue
KG684
KA685
KA864

BC73binding site for residue MG K 1926
ChainResidue
KG985
KG986
MMASP138

BC81binding site for residue MG K 1927
ChainResidue
LLGLY16

BC91binding site for residue MG K 1928
ChainResidue
KA1028

BD11binding site for residue MG K 1929
ChainResidue
KA1035

BD22binding site for residue MG K 1930
ChainResidue
KA1036
KU1072

BD31binding site for residue MG K 1931
ChainResidue
KG1071

BD42binding site for residue MG K 1933
ChainResidue
KG94
KG451

BD53binding site for residue MG K 1934
ChainResidue
KG425
KA426
KU427

BD63binding site for residue MG K 1935
ChainResidue
KA99
KU100
KC409

BD71binding site for residue MG K 1936
ChainResidue
KA99

BD83binding site for residue MG K 1937
ChainResidue
KU43
KA45
KA46

BD91binding site for residue MG K 1938
ChainResidue
KG1197

BE13binding site for residue MG K 1940
ChainResidue
KC492
KC496
KG506

BE22binding site for residue MG K 1941
ChainResidue
KA564
KU580

BE34binding site for residue MG K 1942
ChainResidue
KU34
KC35
KG565
KC579

BE43binding site for residue MG K 1943
ChainResidue
KC603
KA604
KA605

BE51binding site for residue MG K 1945
ChainResidue
KA672

BE63binding site for residue MG K 1946
ChainResidue
KG1385
KG1387
wSER160

BE72binding site for residue MG K 1947
ChainResidue
KG1387
KA1388

BE81binding site for residue MG K 1948
ChainResidue
KA812

BE91binding site for residue MG K 1949
ChainResidue
KC1215

BF14binding site for residue MG K 1950
ChainResidue
KC1216
KA1217
KU1643
KC1644

BF21binding site for residue MG K 1951
ChainResidue
KC1219

BF32binding site for residue MG K 1952
ChainResidue
KG1226
KG1227

BF41binding site for residue MG K 1953
ChainResidue
KA1258

BF53binding site for residue MG K 1954
ChainResidue
KA1259
KA1260
KA1663

BF65binding site for residue MG K 1955
ChainResidue
KC1261
KC1262
KU1263
KG1517
KC1518

BF73binding site for residue MG K 1956
ChainResidue
KU1326
KU1494
KU1496

BF83binding site for residue MG K 1957
ChainResidue
KC1331
KA1489
KG1490

BF94binding site for residue MG K 1958
ChainResidue
KC1331
KA1489
KG1490
KG1491

BG12binding site for residue MG K 1959
ChainResidue
KG1233
KU1519

BG25binding site for residue MG K 1960
ChainResidue
KC1534
KU1535
yALA162
yASN165
yLYS167

BG32binding site for residue MG K 1961
ChainResidue
KG1604
KG1605

BG43binding site for residue MG K 1962
ChainResidue
KG1603
KG1604
KG1605

BG53binding site for residue MG K 1963
ChainResidue
KG1693
KU1694
KG1862

BG64binding site for residue MG K 1964
ChainResidue
KU1830
KA1831
KA1832
KG1837

BG74binding site for residue MG K 1965
ChainResidue
KA1832
KG1837
KU1839
KU1840

BG81binding site for residue MG K 1966
ChainResidue
KU1838

BG91binding site for residue MG K 1967
ChainResidue
KU1839

BH12binding site for residue MG K 1968
ChainResidue
KA599
KG600

BH22binding site for residue MG K 1969
ChainResidue
KG504
KG505

BH32binding site for residue MG K 1970
ChainResidue
KG1227
KC1525

BH41binding site for residue MG K 1971
ChainResidue
KC1262

BH51binding site for residue MG K 1972
ChainResidue
KU1061

BH63binding site for residue MG K 1973
ChainResidue
KG1051
KU1061
KA1062

BH72binding site for residue MG K 1974
ChainResidue
KC1047
KG1048

BH82binding site for residue MG K 1975
ChainResidue
KU1854
KG1855

BH94binding site for residue MG K 1976
ChainResidue
KC1833
KA1834
KU1839
KU1840

BI14binding site for residue MG K 1977
ChainResidue
KG1693
KA1834
KA1835
KA1863

BI23binding site for residue MG K 1978
ChainResidue
KC622
KG623
KA1195

BI32binding site for residue MG K 1979
ChainResidue
KA1589
PPGLY80

BI43binding site for residue MG P 5101
ChainResidue
5U2590
PARG62
PASN64

BI52binding site for residue MG P 5102
ChainResidue
5C1158
PTYR130

BI61binding site for residue MG V 200
ChainResidue
VASN50

BI72binding site for residue MG a 201
ChainResidue
aHIS25
aLYS27

BI85binding site for residue ZN g 201
ChainResidue
gSER44
gCYS46
gCYS49
gCYS83
gCYS86

BI94binding site for residue ZN j 101
ChainResidue
jCYS19
jCYS22
jCYS34
jCYS37

BJ14binding site for residue MG j 102
ChainResidue
5A1093
5A1094
jTHR15
jGLN30

BJ24binding site for residue ZN m 200
ChainResidue
mCYS70
mCYS73
mCYS84
mCYS89

BJ35binding site for residue ZN o 200
ChainResidue
oCYS12
oCYS15
oGLN19
oCYS72
oCYS77

BJ44binding site for residue ZN p 100
ChainResidue
pCYS39
pCYS42
pCYS57
pCYS60

?

Functional Information from PDB atom coordinates for the "HETATM" binding sites

site_idNumber of ResiduesDetails
?

Functional Information from PROSITE/UniProt

site_idNumber of ResiduesDetails
?

Functional Information from SwissProt/UniProt

site_idNumber of ResiduesDetails
?

Catalytic Information from CSA

site_idNumber of ResiduesDetails