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SummaryStructural detailsExperimental detailsFunctional detailsSequence NeighborHistoryDownloads

6R6G

Structure of XBP1u-paused ribosome nascent chain complex with SRP.

This is a non-PDB format compatible entry.
Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
10eS31polymer687986.41UniProt (G1SK22)
Pfam (PF00240)
Pfam (PF01599)
In PDB		Oryctolagus cuniculus (Rabbit)
21X-box-binding protein 1polymer242895.41UniProt (P17861)
In PDB		Homo sapiens (Human)XBP-1,Tax-responsive element-binding protein 5,TREB-5
32P-tRNApolymer7524108.31Saccharomyces cerevisiae (Baker's yeast)
43E-tRNApolymer7524148.41Saccharomyces cerevisiae (Baker's yeast)
54mRNApolymer61877.21Homo sapiens
6528S ribosomal RNApolymer35441148420.61Oryctolagus cuniculus (Rabbit)
76ribosomal protein RACK1polymer31334669.11UniProt (G1SJB4)
Pfam (PF00400)
In PDB		Oryctolagus cuniculus (Rabbit)
875S ribosomal RNApolymer12038691.91Oryctolagus cuniculus (Rabbit)
985.8S ribosomal RNApolymer15148545.71Oryctolagus cuniculus (Rabbit)
109uS14polymer556559.61UniProt (G1U7M4)
Pfam (PF00253)
In PDB		Oryctolagus cuniculus (Rabbit)
11AuL2polymer24826998.61UniProt (G1TT27)
Pfam (PF03947)
Pfam (PF00181)
In PDB		Oryctolagus cuniculus (Rabbit)
12AA40S ribosomal protein S30polymer556317.51UniProt (G1T8A2)
Pfam (PF04758)
In PDB		Oryctolagus cuniculus (Rabbit)
13BuL3polymer39445119.81UniProt (G1TL06)
Pfam (PF00297)
In PDB		Oryctolagus cuniculus (Rabbit)
14BB40S ribosomal protein S7polymer18921629.31UniProt (G1SVB0)
In PDB		Oryctolagus cuniculus (Rabbit)
15CuL4polymer36241101.41UniProt (G1SVW5)
Pfam (PF00573)
Pfam (PF14374)
In PDB		Oryctolagus cuniculus (Rabbit)
16CC40S ribosomal protein S8polymer20624003.01UniProt (G1TJW1)
Pfam (PF01201)
In PDB		Oryctolagus cuniculus (Rabbit)
17DDRibosomal protein S9 (Predicted)polymer18521649.61UniProt (B7NZS8)
Pfam (PF00163)
Pfam (PF01479)
In PDB		Oryctolagus cuniculus (Rabbit)
18D60S ribosomal protein L5polymer29334077.41UniProt (G1SYJ6)
UniProt (by SIFTS) (P19949)
In PDB		Oryctolagus cuniculus (Rabbit)
19EERibosomal protein S11polymer15117586.81UniProt (G1TRM4)
Pfam (PF16205)
Pfam (PF00366)
In PDB		Oryctolagus cuniculus (Rabbit)
20E60S ribosomal protein L6polymer25128818.31UniProt (G1SKF7)
Pfam (PF03868)
Pfam (PF01159)
In PDB		Oryctolagus cuniculus (Rabbit)
21FFRibosomal protein S28polymer627007.11UniProt (G1TIB4)
Pfam (PF01200)
In PDB		Oryctolagus cuniculus (Rabbit)
22FuL30polymer22526658.81UniProt (G1SV32)
Pfam (PF08079)
Pfam (PF00327)
In PDB		Oryctolagus cuniculus (Rabbit)
23GGRibosomal protein S20polymer10011395.51Oryctolagus cuniculus (Rabbit)uS10
24GeL8polymer24027351.41UniProt (G1STW0)
Pfam (PF01248)
In PDB		Oryctolagus cuniculus (Rabbit)
25HuL6polymer19021627.21UniProt (G1TX33)
Pfam (PF00347)
UniProt (by SIFTS) (G1SWI6)
In PDB		Oryctolagus cuniculus (Rabbit)
26HH40S ribosomal protein S21polymer839124.41Oryctolagus cuniculus (Rabbit)eS21
27IRibosomal protein L10 (Predicted)polymer21324511.91UniProt (B7NZQ2)
Pfam (PF00252)
In PDB		Oryctolagus cuniculus (Rabbit)
28IIuS13polymer14416898.61UniProt (G1SZI5)
Pfam (PF00416)
UniProt (by SIFTS) (G1TPG3)
In PDB		Oryctolagus cuniculus (Rabbit)
29JJ40S ribosomal protein S27polymer839349.01UniProt (G1TZ76)
Pfam (PF01667)
In PDB		Oryctolagus cuniculus (Rabbit)
30JRibosomal protein L11polymer17019399.51UniProt (G1TUB8)
Pfam (PF00281)
Pfam (PF00673)
In PDB		Oryctolagus cuniculus (Rabbit)
31K18S ribosomal RNApolymer1698548040.21Oryctolagus cuniculus (Rabbit)
32KKeS17polymer13215250.71UniProt (G1TU13)
Pfam (PF00833)
In PDB		Oryctolagus cuniculus (Rabbit)
33L60S ribosomal protein L13polymer21024200.51UniProt (G1TPV0)
In PDB		Oryctolagus cuniculus (Rabbit)
34LL40S ribosomal protein S26polymer10111645.81Oryctolagus cuniculus (Rabbit)eS26
35MRibosomal protein L14polymer13816217.41UniProt (U3KNW6)
Pfam (PF01929)
UniProt (by SIFTS) (G1SZ12)
In PDB		Oryctolagus cuniculus (Rabbit)
36MM40S ribosomal protein S14polymer13614544.71Oryctolagus cuniculus (Rabbit)uS11
37NRibosomal protein L15polymer20324076.11UniProt (G1T0C1)
Pfam (PF00827)
In PDB		Oryctolagus cuniculus (Rabbit)
38NN40S ribosomal protein S24polymer12414432.11Oryctolagus cuniculus (Rabbit)eS24
39O60S ribosomal protein L13apolymer19923144.91Oryctolagus cuniculus (Rabbit)uL13
40OOribosomal protein eS25polymer758526.11UniProt (G1TDB3)
Pfam (PF03297)
In PDB		Oryctolagus cuniculus (Rabbit)
41PuL22polymer15317758.71UniProt (G1TVT6)
Pfam (PF00237)
UniProt (by SIFTS) (G1SCJ6)
In PDB		Oryctolagus cuniculus (Rabbit)
42PPeS19polymer14115611.01UniProt (G1TN62)
Pfam (PF01090)
In PDB		Oryctolagus cuniculus (Rabbit)
43QeL18polymer18721568.51UniProt (G1TX70)
Pfam (PF17135)
In PDB		Oryctolagus cuniculus (Rabbit)
44QQribosomal protein uS15polymer14917057.11UniProt (G1SP51)
Pfam (PF08069)
Pfam (PF00312)
In PDB		Oryctolagus cuniculus (Rabbit)
45R60S ribosomal protein L19polymer18021613.01Oryctolagus cuniculus (Rabbit)eL19
46RR40S ribosomal protein S12polymer11713048.21UniProt (G1SFR8)
Pfam (PF01248)
In PDB		Oryctolagus cuniculus (Rabbit)
47SeL20polymer17620827.61Oryctolagus cuniculus (Rabbit)
48SSeS10polymer9611529.71UniProt (G1TPV3)
Pfam (PF03501)
In PDB		Oryctolagus cuniculus (Rabbit)
49TeL21polymer15918478.81UniProt (G1SHQ2)
Pfam (PF01157)
In PDB		Oryctolagus cuniculus (Rabbit)
50TTRibosomal protein S15apolymer12914734.41UniProt (G1TG89)
Pfam (PF00410)
In PDB		Oryctolagus cuniculus (Rabbit)
51UURibosomal protein S16polymer14216032.81UniProt (G1SGX4)
Pfam (PF00380)
In PDB		Oryctolagus cuniculus (Rabbit)
52U60S ribosomal protein L22polymer9911495.31Oryctolagus cuniculus (Rabbit)eL22
53VVRibosomal protein S23polymer14115626.41UniProt (G1SZ47)
Pfam (PF00164)
In PDB		Oryctolagus cuniculus (Rabbit)
54VeL14polymer13113972.41UniProt (G1T6D1)
Pfam (PF00238)
In PDB		Oryctolagus cuniculus (Rabbit)
55WRibosomal protein L24polymer12114131.51UniProt (G1SE28)
Pfam (PF01246)
In PDB		Oryctolagus cuniculus (Rabbit)
56WWuS19polymer12014246.91UniProt (G1U0Q2)
Pfam (PF00203)
In PDB		Oryctolagus cuniculus (Rabbit)
57XuL23polymer11813727.21UniProt (G1SE76)
Pfam (PF03939)
Pfam (PF00276)
In PDB		Oryctolagus cuniculus (Rabbit)
58YRibosomal protein L26polymer13415891.81UniProt (G1SQH0)
Pfam (PF16906)
Pfam (PF00467)
In PDB		Oryctolagus cuniculus (Rabbit)
59Z60S ribosomal protein L27polymer13515704.61UniProt (G1TXF6)
Pfam (PF00467)
Pfam (PF01777)
In PDB		Oryctolagus cuniculus (Rabbit)
60auL15polymer14716489.41UniProt (G1SNY0)
Pfam (PF00828)
In PDB		Oryctolagus cuniculus (Rabbit)
61beL29polymer11613401.01UniProt (G1SGR6)
Pfam (PF01779)
In PDB		Oryctolagus cuniculus (Rabbit)
62ceL30polymer9810914.81UniProt (G1TDL2)
Pfam (PF01248)
In PDB		Oryctolagus cuniculus (Rabbit)
63deL31polymer10712635.71UniProt (G1SHG0)
Pfam (PF01198)
In PDB		Oryctolagus cuniculus (Rabbit)
64eeL32polymer12815022.01UniProt (G1TUN8)
Pfam (PF01655)
In PDB		Oryctolagus cuniculus (Rabbit)
65feL33polymer10912449.61UniProt (G1SF08)
Pfam (PF01247)
In PDB		Oryctolagus cuniculus (Rabbit)
66geL34polymer11412994.61UniProt (G1U945)
Pfam (PF01199)
UniProt (by SIFTS) (G1TXG5)
In PDB		Oryctolagus cuniculus (Rabbit)
67huL29polymer12214435.41UniProt (G1SIT5)
Pfam (PF00831)
In PDB		Oryctolagus cuniculus (Rabbit)
68i60S ribosomal protein L36polymer10211888.41UniProt (G1TTQ5)
Pfam (PF01158)
In PDB		Oryctolagus cuniculus (Rabbit)
69jRibosomal protein L37polymer8610090.91UniProt (U3KPD5)
Pfam (PF01907)
In PDB		Oryctolagus cuniculus (Rabbit)
70k60S ribosomal protein L38polymer698107.81Oryctolagus cuniculus (Rabbit)eL38
71leL39polymer506324.61UniProt (G1TTN1)
Pfam (PF00832)
In PDB		Oryctolagus cuniculus (Rabbit)
72m60S ribosomal protein L40polymer526199.61Oryctolagus cuniculus (Rabbit)eL40
73n60s ribosomal protein l41polymer253473.51UniProt (A0A087WNH4)
Pfam (PF05162)
In PDB		Oryctolagus cuniculus (Rabbit)eL41
74oeL42polymer10412198.61UniProt (G1T040)
Pfam (PF00935)
In PDB		Oryctolagus cuniculus (Rabbit)
75pribosomal protein eL43polymer9110168.21UniProt (G1SY53)
Pfam (PF01780)
In PDB		Oryctolagus cuniculus (Rabbit)
76quS2polymer21724361.91Oryctolagus cuniculus (Rabbit)
77reL28polymer12414220.71UniProt (G1U7L1)
Pfam (PF01778)
In PDB		Oryctolagus cuniculus (Rabbit)
78s60S acidic ribosomal protein P0polymer19621521.11UniProt (G1U6N2)
In PDB		Oryctolagus cuniculus (Rabbit)
79tuL11polymer15316561.11UniProt (G1SMR7)
Pfam (PF03946)
Pfam (PF00298)
In PDB		Oryctolagus cuniculus (Rabbit)
80u40S ribosomal protein S3apolymer21324759.11UniProt (G1SS70)
Pfam (PF01015)
In PDB		Oryctolagus cuniculus (Rabbit)
81vuS5polymer22124441.81Oryctolagus cuniculus (Rabbit)
82wRibosomal protein S3polymer22825215.61UniProt (G1TNM3)
Pfam (PF07650)
Pfam (PF00189)
In PDB		Oryctolagus cuniculus (Rabbit)
83x40S ribosomal protein S4polymer26229523.71UniProt (G1TK17)
Pfam (PF08071)
Pfam (PF00900)
Pfam (PF00467)
Pfam (PF16121)
In PDB		Oryctolagus cuniculus (Rabbit)
84yRibosomal protein S5polymer19121525.91UniProt (G1TFM5)
Pfam (PF00177)
In PDB		Oryctolagus cuniculus (Rabbit)
85z40S ribosomal protein S6polymer23727471.51UniProt (G1TM55)
Pfam (PF01092)
In PDB		Oryctolagus cuniculus (Rabbit)
86ABSignal recognition particle 54 kDa proteinpolymer43147844.21UniProt (P61010)
Pfam (PF02881)
Pfam (PF00448)
Pfam (PF02978)
In PDB		Canis lupus familiaris (Dog)SRP54
87AF7S RNApolymer20666779.71Canis lupus familiaris (Dog)
88ACSignal recognition particle subunit SRP19polymer10512159.21UniProt (J9PAS6)
Pfam (PF01922)
In PDB		Canis lupus familiaris (Dog)
89AISignal recognition particle subunit SRP68polymer19523220.71UniProt (Q00004)
Pfam (PF16969)
In PDB		Canis lupus familiaris (Dog)SRP68,Signal recognition particle 68 kDa protein
90ADSignal recognition particle 9 kDa proteinpolymer748705.11UniProt (F1Q0Z5)
In PDB		Canis lupus familiaris (Dog)SRP9
91AESignal recognition particle 14 kDa proteinpolymer9410651.41UniProt (P16255)
Pfam (PF02290)
In PDB		Canis lupus familiaris (Dog)SRP14
92AGSignal sequence (HR2)polymer121375.91Homo sapiens (Human)
935, K, j, 7, 8...MAGNESIUM IONnon-polymer24.3299Chemie (MG)
94g, j, m, o, pZINC IONnon-polymer65.45Chemie (ZN)
Sequence modifications
1: 237 - 260 (UniProt: P17861)
PDBExternal DatabaseDetails
Ala 255Ser 255conflict
CC: 2 - 207 (UniProt: G1TJW1)
PDBExternal DatabaseDetails
Arg 47Gly 47conflict
G: 80 - 319 (UniProt: G1STW0)
PDBExternal DatabaseDetails
Gly 244Cys 167conflict
L: 2 - 211 (UniProt: G1TPV0)
PDBExternal DatabaseDetails
Ala 47-insertion
Pro 48-insertion
Arg 49-insertion
Pro 50-insertion
Ala 51-insertion
Ala 52-insertion
Gly 53-insertion
Pro 54-insertion
Ile 55-insertion
PP: 3 - 143 (UniProt: G1TN62)
PDBExternal DatabaseDetails
Gly 119Trp 119conflict
Q: 2 - 188 (UniProt: G1TX70)
PDBExternal DatabaseDetails
Arg 6Leu 6conflict
Arg 14Trp 14conflict
Ile 23Met 23conflict
Tyr 24Cys 24conflict
Arg 38His 38conflict
Asn 57Lys 57conflict
Met 66Val 66conflict
Gly 74Asp 74conflict
Arg 75Pro 75conflict
Val 86Ile 86conflict
Arg 110His 110conflict
Gly 117Glu 117conflict
Asp 124His 124conflict
Arg 150Gln 150conflict
Arg 172Gly 172conflict
Arg 184Trp 184conflict
x: 2 - 263 (UniProt: G1TK17)
PDBExternal DatabaseDetails
Gly 25Ser 25conflict
Arg 51Lys 51conflict
Thr 78Ala 78conflict
Val 156Met 156conflict
AD: 2 - 75 (UniProt: F1Q0Z5)
PDBExternal DatabaseDetails
Asn 37Ser 37conflict
Val 40Ile 40conflict
Lys 52Arg 52conflict
AE: 2 - 95 (UniProt: P16255)
PDBExternal DatabaseDetails
Thr 22Leu 22conflict
Tyr 27Phe 27conflict
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains92
Total formula weight3358794.4
Non-Polymers*Number of molecules304
Total formula weight7594.2
All*Total formula weight3366388.7
*Water molecules are not included.

225158

PDB entries from 2024-09-18

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