Loading
PDBj
English日本語简体中文繁體中文한국어
✖
ﾒﾆｭｰPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help
PDB: 12 件
6BSX
DownloadVisualize
BU of 6bsx by Molmil
CRYSTAL STRUCTURE OF RHEB IN COMPLEX WITH COMPOUND 1 AT 1.65A RESOLUTION
分子名称: (5,6-dimethyl-1H-benzimidazol-2-yl)methanol, 1,2-ETHANEDIOL, ACETATE ION, ...
著者Mahoney, S.J.
登録日2017-12-04
公開日2018-02-28
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献A small molecule inhibitor of Rheb selectively targets mTORC1 signaling.
Nat Commun, 9, 2018
3T5G
DownloadVisualize
BU of 3t5g by Molmil
Structure of fully modified farnesylated Rheb in complex with PDE6D
分子名称: FARNESYL, GTP-binding protein Rheb, GUANOSINE-5'-DIPHOSPHATE, ...
著者Ismail, S.A, Chen, Y.-X, Wittinghofer, A.
登録日2011-07-27
公開日2011-10-26
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Arl2-GTP and Arl3-GTP regulate a GDI-like transport system for farnesylated cargo.
Nat.Chem.Biol., 7, 2011
3SEA
DownloadVisualize
BU of 3sea by Molmil
Structure of Rheb-Y35A mutant in GDP- and GMPPNP-bound forms
分子名称: ACETATE ION, GTP-binding protein Rheb, GUANOSINE-5'-DIPHOSPHATE, ...
著者Mazhab-Jafari, M.T, Marshall, C.B, Ishiyama, N, Vuk, S, Ikura, M.
登録日2011-06-10
公開日2012-06-20
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献An Autoinhibited Noncanonical Mechanism of GTP Hydrolysis by Rheb Maintains mTORC1 Homeostasis.
Structure, 20, 2012
7BTD
DownloadVisualize
BU of 7btd by Molmil
Crystal structure of Rheb Y35N mutant bound to GppNHp
分子名称: GTP-binding protein Rheb, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER
著者Zhang, C, Zhang, T, Ding, J.
登録日2020-04-01
公開日2020-06-17
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Molecular basis for the functions of dominantly active Y35N and inactive D60K Rheb mutants in mTORC1 signaling.
J Mol Cell Biol, 12, 2020
1XTQ
DownloadVisualize
BU of 1xtq by Molmil
Structure of small GTPase human Rheb in complex with GDP
分子名称: GTP-binding protein Rheb, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION
著者Yu, Y, Ding, J.
登録日2004-10-24
公開日2005-03-08
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural Basis for the Unique Biological Function of Small GTPase RHEB
J.Biol.Chem., 280, 2005
5YXH
DownloadVisualize
BU of 5yxh by Molmil
Structure of Rheb-GDP
分子名称: GTP-binding protein Rheb, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION
著者Mahoney, S.J.
登録日2017-12-05
公開日2018-02-28
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.04 Å)
主引用文献A small molecule inhibitor of Rheb selectively targets mTORC1 signaling.
Nat Commun, 9, 2018
7BTC
DownloadVisualize
BU of 7btc by Molmil
Crystal structure of Rheb Y35N mutant bound to GDP
分子名称: GTP-binding protein Rheb, GUANOSINE-5'-DIPHOSPHATE
著者Zhang, C, Zhang, T, Ding, J.
登録日2020-04-01
公開日2020-06-17
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.101 Å)
主引用文献Molecular basis for the functions of dominantly active Y35N and inactive D60K Rheb mutants in mTORC1 signaling.
J Mol Cell Biol, 12, 2020
7BTA
DownloadVisualize
BU of 7bta by Molmil
Crystal structure of Rheb D60K mutant bound to GDP
分子名称: GTP-binding protein Rheb, GUANOSINE-5'-DIPHOSPHATE, PHOSPHATE ION
著者Zhang, C, Zhang, T, Ding, J.
登録日2020-03-31
公開日2020-06-17
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Molecular basis for the functions of dominantly active Y35N and inactive D60K Rheb mutants in mTORC1 signaling.
J Mol Cell Biol, 12, 2020
6BT0
DownloadVisualize
BU of 6bt0 by Molmil
CRYSTAL STRUCTURE OF RHEB IN COMPLEX WITH COMPOUND NR1
分子名称: 4-bromo-6-[(3,4-dichlorophenyl)sulfanyl]-1-{[4-(dimethylcarbamoyl)phenyl]methyl}-1H-indole-2-carboxylic acid, GTP-binding protein Rheb, GUANOSINE-5'-DIPHOSPHATE, ...
著者Mahoney, S.J.
登録日2017-12-04
公開日2018-02-28
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献A small molecule inhibitor of Rheb selectively targets mTORC1 signaling.
Nat Commun, 9, 2018
1XTR
DownloadVisualize
BU of 1xtr by Molmil
Structure of small GTPase human Rheb in complex with GppNHp
分子名称: GLYCEROL, GTP-binding protein Rheb, MAGNESIUM ION, ...
著者Yu, Y, Ding, J.
登録日2004-10-24
公開日2005-03-08
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.65 Å)
主引用文献Structural Basis for the Unique Biological Function of Small GTPase RHEB
J.Biol.Chem., 280, 2005
1XTS
DownloadVisualize
BU of 1xts by Molmil
Structure of small GTPase human Rheb in complex with GTP
分子名称: GTP-binding protein Rheb, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION
著者Yu, Y, Ding, J.
登録日2004-10-24
公開日2005-03-08
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structural Basis for the Unique Biological Function of Small GTPase RHEB
J.Biol.Chem., 280, 2005
6BCU
DownloadVisualize
BU of 6bcu by Molmil
Cryo-EM structure of the activated RHEB-mTORC1 refined to 3.4 angstrom
分子名称: ADENOSINE-5'-TRIPHOSPHATE, Eukaryotic translation initiation factor 4E-binding protein 1, GTP-binding protein Rheb, ...
著者Pavletich, N.P, Yang, H.
登録日2017-10-20
公開日2017-12-20
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Mechanisms of mTORC1 activation by RHEB and inhibition by PRAS40.
Nature, 552, 2017

222415

件を2024-07-10に公開中

PDB statisticsPDBj update infoContact PDBjnumon