7BTD

Crystal structure of Rheb Y35N mutant bound to GppNHp

Summary for 7BTD

• Entry DOI: 10.2210/pdb7btd/pdb
• Descriptor: GTP-binding protein Rheb, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ... (4 entities in total)
• Functional Keywords: mtorc1, small gtpase, rheb, signaling protein
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 1
• Total formula weight: 20646.40

Authors

Zhang, C.,Zhang, T.,Ding, J. (deposition date: 2020-04-01, release date: 2020-06-17, Last modification date: 2023-11-29)

• Primary citation: Zhang, C.,Liu, Y.,Zhang, Y.,Wang, X.,Zhang, T.,Ding, J.; Molecular basis for the functions of dominantly active Y35N and inactive D60K Rheb mutants in mTORC1 signaling.; J Mol Cell Biol, 12:741-744, 2020; PubMed: 32470140; DOI: 10.1093/jmcb/mjaa025

Experimental method

X-RAY DIFFRACTION (2 Å)