7BTD
Crystal structure of Rheb Y35N mutant bound to GppNHp
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | GTP-binding protein Rheb | polymer | 177 | 20099.9 | 1 | UniProt (Q15382) Pfam (PF00071) | Homo sapiens (Human) | Ras homolog enriched in brain |
| 2 | B (A) | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
| 3 | C (A) | PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER | non-polymer | 522.2 | 1 | Chemie (GNP) | |||
| 4 | D (A) | water | water | 18.0 | 105 | Chemie (HOH) |
Sequence modifications
A: 1 - 169 (UniProt: Q15382)
| PDB | External Database | Details |
|---|---|---|
| Asn 35 | Tyr 35 | engineered mutation |
| Leu 170 | - | expression tag |
| Glu 171 | - | expression tag |
| His 172 | - | expression tag |
| His 173 | - | expression tag |
| His 174 | - | expression tag |
| His 175 | - | expression tag |
| His 176 | - | expression tag |
| His 177 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 20099.9 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 546.5 | |
| All* | Total formula weight | 20646.4 |
