7BTC

Crystal structure of Rheb Y35N mutant bound to GDP

Summary for 7BTC

Entry DOI	10.2210/pdb7btc/pdb
Descriptor	GTP-binding protein Rheb, GUANOSINE-5'-DIPHOSPHATE (3 entities in total)
Functional Keywords	mtorc1, small gtpase, rheb, signaling protein
Biological source	Homo sapiens (Human)
Total number of polymer chains	4
Total formula weight	82172.38
Authors	Zhang, C.,Zhang, T.,Ding, J. (deposition date: 2020-04-01, release date: 2020-06-17, Last modification date: 2023-11-29)
Primary citation	Zhang, C.,Liu, Y.,Zhang, Y.,Wang, X.,Zhang, T.,Ding, J. Molecular basis for the functions of dominantly active Y35N and inactive D60K Rheb mutants in mTORC1 signaling. J Mol Cell Biol, 12:741-744, 2020 Cited by PubMed: 32470140 DOI: 10.1093/jmcb/mjaa025 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.101 Å)

Structure validation