6BSX
CRYSTAL STRUCTURE OF RHEB IN COMPLEX WITH COMPOUND 1 AT 1.65A RESOLUTION
Summary for 6BSX
Entry DOI | 10.2210/pdb6bsx/pdb |
Related | 1XTQ |
Descriptor | GTP-binding protein Rheb, MAGNESIUM ION, ACETATE ION, ... (7 entities in total) |
Functional Keywords | mtorc1 g-protein, signaling protein |
Biological source | Homo sapiens (Human) |
Cellular location | Endomembrane system ; Lipid-anchor ; Cytoplasmic side : Q15382 |
Total number of polymer chains | 4 |
Total formula weight | 84003.51 |
Authors | Mahoney, S.J. (deposition date: 2017-12-04, release date: 2018-02-28, Last modification date: 2023-10-04) |
Primary citation | Mahoney, S.J.,Narayan, S.,Molz, L.,Berstler, L.A.,Kang, S.A.,Vlasuk, G.P.,Saiah, E. A small molecule inhibitor of Rheb selectively targets mTORC1 signaling. Nat Commun, 9:548-548, 2018 Cited by PubMed: 29416044DOI: 10.1038/s41467-018-03035-z PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.65 Å) |
Structure validation
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