6BSX

CRYSTAL STRUCTURE OF RHEB IN COMPLEX WITH COMPOUND 1 AT 1.65A RESOLUTION

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D (A, B, C, D)	GTP-binding protein Rheb	polymer	178	20236.0	4	UniProt (Q15382) Pfam (PF00071)	Homo sapiens (Human)	Ras homolog enriched in brain
2	E, J, O, T (A, B, C, D)	MAGNESIUM ION	non-polymer		24.3	4	Chemie (MG)
3	F, K, P, U (A, B, C, D)	ACETATE ION	non-polymer		59.0	4	Chemie (ACT)
4	G, L, Q, V (A, B, C, D)	GUANOSINE-5'-DIPHOSPHATE	non-polymer		443.2	4	Chemie (GDP)
5	H, M, R, W (A, B, C, D)	(5,6-dimethyl-1H-benzimidazol-2-yl)methanol	non-polymer		176.2	4	Chemie (E7S)
6	I, N, S, X (A, B, C, D)	1,2-ETHANEDIOL	non-polymer		62.1	4	Chemie (EDO)
7	AA, BA, Y, Z (C, D, A, B)	water	water		18.0	544	Chemie (HOH)

Sequence modifications

A, B, C, D: 1 - 169 (UniProt: Q15382)

PDB	External Database	Details
Ser 0	-	expression tag
Leu 170	-	expression tag
Glu 171	-	expression tag
His 172	-	expression tag
His 173	-	expression tag
His 174	-	expression tag
His 175	-	expression tag
His 176	-	expression tag
His 177	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	80944.2
Non-Polymers*	Number of molecules	20
	Total formula weight	3059.3
All*	Total formula weight	84003.5

*Water molecules are not included.