6BSX

CRYSTAL STRUCTURE OF RHEB IN COMPLEX WITH COMPOUND 1 AT 1.65A RESOLUTION

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D	GTP-binding protein Rheb	polymer	178	20236.0	4	UniProt (Q15382) Pfam (PF00071) In PDB	Homo sapiens (Human)	Ras homolog enriched in brain
2	A, B, C, D	MAGNESIUM ION	non-polymer		24.3	4	Chemie (MG)
3	A, B, C, D	ACETATE ION	non-polymer		59.0	4	Chemie (ACT)
4	A, B, C, D	GUANOSINE-5'-DIPHOSPHATE	non-polymer		443.2	4	Chemie (GDP)
5	A, B, C, D	(5,6-dimethyl-1H-benzimidazol-2-yl)methanol	non-polymer		176.2	4	Chemie (E7S)
6	A, B, C, D	1,2-ETHANEDIOL	non-polymer		62.1	4	Chemie (EDO)
7		water	water		18.0	544	Chemie (HOH)

Sequence modifications

A, B, C, D: 1 - 169 (UniProt: Q15382)

PDB	External Database	Details
Ser 0	-	expression tag
Leu 170	-	expression tag
Glu 171	-	expression tag
His 172	-	expression tag
His 173	-	expression tag
His 174	-	expression tag
His 175	-	expression tag
His 176	-	expression tag
His 177	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	80944.2
Non-Polymers*	Number of molecules	20
	Total formula weight	3059.3
All*	Total formula weight	84003.5

*Water molecules are not included.