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3T5G

Structure of fully modified farnesylated Rheb in complex with PDE6D

Summary for 3T5G
Entry DOI10.2210/pdb3t5g/pdb
Related3T5I
DescriptorGTP-binding protein Rheb, Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta, GUANOSINE-5'-DIPHOSPHATE, ... (6 entities in total)
Functional Keywordsimmunoglobulin-like beta sandwitch, pde delta, rheb, farnesyl, signaling protein, lipid binding protein
Biological sourceHomo sapiens (human)
More
Cellular locationEndomembrane system ; Lipid-anchor ; Cytoplasmic side : Q15382
Cytoplasm, cytosol : O43924
Total number of polymer chains2
Total formula weight38507.13
Authors
Ismail, S.A.,Chen, Y.-X.,Wittinghofer, A. (deposition date: 2011-07-27, release date: 2011-10-26, Last modification date: 2023-09-13)
Primary citationIsmail, S.A.,Chen, Y.X.,Rusinova, A.,Chandra, A.,Bierbaum, M.,Gremer, L.,Triola, G.,Waldmann, H.,Bastiaens, P.I.,Wittinghofer, A.
Arl2-GTP and Arl3-GTP regulate a GDI-like transport system for farnesylated cargo.
Nat.Chem.Biol., 7:942-949, 2011
Cited by
PubMed: 22002721
DOI: 10.1038/nchembio.686
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.7 Å)
Structure validation

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