3T5G
Structure of fully modified farnesylated Rheb in complex with PDE6D
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | GTP-binding protein Rheb | polymer | 181 | 20248.1 | 1 | UniProt (Q15382) Pfam (PF00071) | Homo sapiens (human) | Ras homolog enriched in brain |
| 2 | B (B) | Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta | polymer | 152 | 17585.1 | 1 | UniProt (O43924) Pfam (PF05351) | Homo sapiens (human) | GMP-PDE delta, Protein p17 |
| 3 | C (A) | GUANOSINE-5'-DIPHOSPHATE | non-polymer | 443.2 | 1 | Chemie (GDP) | |||
| 4 | D (A) | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
| 5 | E (A) | FARNESYL | non-polymer | 206.4 | 1 | Chemie (FAR) | |||
| 6 | F, G (A, B) | water | water | 18.0 | 416 | Chemie (HOH) |
Sequence modifications
A: 1 - 181 (UniProt: Q15382)
B: 1 - 150 (UniProt: O43924)
| PDB | External Database | Details |
|---|---|---|
| Cys 174 | Ala 174 | engineered mutation |
| PDB | External Database | Details |
|---|---|---|
| Gly -1 | - | expression tag |
| Ser 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 37833.3 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 673.9 | |
| All* | Total formula weight | 38507.1 |
