3T5G
Structure of fully modified farnesylated Rheb in complex with PDE6D
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | GTP-binding protein Rheb | polymer | 181 | 20248.1 | 1 | UniProt (Q15382) Pfam (PF00071) In PDB | Homo sapiens (human) | Ras homolog enriched in brain |
2 | B | Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta | polymer | 152 | 17585.1 | 1 | UniProt (O43924) Pfam (PF05351) In PDB | Homo sapiens (human) | GMP-PDE delta, Protein p17 |
3 | A | GUANOSINE-5'-DIPHOSPHATE | non-polymer | 443.2 | 1 | Chemie (GDP) | |||
4 | A | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
5 | A | FARNESYL | non-polymer | 206.4 | 1 | Chemie (FAR) | |||
6 | water | water | 18.0 | 416 | Chemie (HOH) |
Sequence modifications
A: 1 - 181 (UniProt: Q15382)
B: 1 - 150 (UniProt: O43924)
PDB | External Database | Details |
---|---|---|
Cys 174 | Ala 174 | engineered mutation |
PDB | External Database | Details |
---|---|---|
Gly -1 | - | expression tag |
Ser 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 37833.3 | |
Non-Polymers* | Number of molecules | 3 |
Total formula weight | 673.9 | |
All* | Total formula weight | 38507.1 |