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PDB: 36 件

4ZIE
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BU of 4zie by Molmil
Crystal Structure of core/latch dimer of Bax in complex with BimBH3
分子名称: 1,2-ETHANEDIOL, Apoptosis regulator BAX, Bcl-2-like protein 11
著者Krishna Kumar, K, Robin, A.Y, Westphal, D, Wardak, A.Z, Thompson, G.V, Dewson, G, Colman, P.M, Czabotar, P.E.
登録日2015-04-28
公開日2015-07-22
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.797 Å)
主引用文献Crystal structure of Bax bound to the BH3 peptide of Bim identifies important contacts for interaction.
Cell Death Dis, 6, 2015
5W60
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BU of 5w60 by Molmil
Crystal structure of BAXP168G monomer cryo-protected with ethylene glycol
分子名称: Apoptosis regulator BAX, SULFATE ION
著者Robin, A.Y, Colman, P.M, Czabotar, P.E.
登録日2017-06-16
公開日2018-06-27
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.803 Å)
主引用文献Ensemble Properties of Bax Determine Its Function.
Structure, 26, 2018
4S0O
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BU of 4s0o by Molmil
Crystal Structure of the Autoinhibited Dimer of Pro-apoptotic BAX (I)
分子名称: Apoptosis regulator BAX
著者Priyadarshi, A, Gavathiotis, E.
登録日2015-01-02
公開日2016-07-20
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献An Autoinhibited Dimeric Form of BAX Regulates the BAX Activation Pathway.
Mol.Cell, 63, 2016
5W5Z
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BU of 5w5z by Molmil
Crystal structure of BAXP168G in complex with an activating antibody at high resolution
分子名称: 1,2-ETHANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 3C10 Fab heavy chain, ...
著者Robin, A.Y, Colman, P.M, Czabotar, P.E.
登録日2017-06-16
公開日2018-06-27
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.997 Å)
主引用文献Ensemble Properties of Bax Determine Its Function.
Structure, 26, 2018
6EB6
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BU of 6eb6 by Molmil
Crystal structure of BAX W139A monomer
分子名称: Apoptosis regulator BAX, FORMIC ACID
著者Robin, A.Y.
登録日2018-08-05
公開日2019-04-10
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.023 Å)
主引用文献BAX Activation: Mutations Near Its Proposed Non-canonical BH3 Binding Site Reveal Allosteric Changes Controlling Mitochondrial Association.
Cell Rep, 27, 2019
8SRX
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BU of 8srx by Molmil
Crystal structure of BAK-BAX heterodimer with lysoPC
分子名称: 1,2-ETHANEDIOL, Apoptosis regulator BAX, Bcl-2 homologous antagonist/killer, ...
著者Brouwer, J.M, Czabotar, P.E, Colman, P.M, Miller, M.S.
登録日2023-05-07
公開日2023-12-27
最終更新日2024-06-19
実験手法X-RAY DIFFRACTION (2.09 Å)
主引用文献Sequence differences between BAX and BAK core domains manifest as differences in their interactions with lipids.
Febs J., 291, 2024
8G1T
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BU of 8g1t by Molmil
Crystal structure of Bax core domain BH3-groove dimer - tetrameric fraction P21
分子名称: 1,2-ETHANEDIOL, Apoptosis regulator BAX
著者Cowan, A.D, Colman, P.M, Czabotar, P.E, Miller, M.S.
登録日2023-02-02
公開日2023-12-27
最終更新日2024-06-19
実験手法X-RAY DIFFRACTION (2.092 Å)
主引用文献Sequence differences between BAX and BAK core domains manifest as differences in their interactions with lipids.
Febs J., 291, 2024
6TRR
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BU of 6trr by Molmil
Structural insight into tanapoxvirus mediated inhibition of apoptosis
分子名称: 16L protein, Apoptosis regulator BAX, SODIUM ION
著者Suraweera, C.D, Hinds, M.G, Kvansakul, M.
登録日2019-12-19
公開日2020-06-03
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.12007356 Å)
主引用文献Structural insight into tanapoxvirus-mediated inhibition of apoptosis.
Febs J., 287, 2020
4ZII
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BU of 4zii by Molmil
Crystal Structure of core/latch dimer of BaxI66A in complex with BidBH3
分子名称: 1,2-ETHANEDIOL, Apoptosis regulator BAX, BH3-interacting domain death agonist
著者Czabotar, P.E, Robin, A.Y, Krishna Kumar, K, Westphal, D, Wardak, A.Z, Thompson, G.V, Dewson, G, Colman, P.M.
登録日2015-04-28
公開日2015-07-22
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.191 Å)
主引用文献Crystal structure of Bax bound to the BH3 peptide of Bim identifies important contacts for interaction.
Cell Death Dis, 6, 2015
8SPF
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BU of 8spf by Molmil
Crystal structure of Bax core domain BH3-groove dimer - hexameric fraction with 2-stearoyl lysoPC
分子名称: 1,2-ETHANEDIOL, Apoptosis regulator BAX, DODECANE, ...
著者Cowan, A.D, Miller, M.S, Czabotar, P.E, Colman, P.M.
登録日2023-05-03
公開日2023-12-27
最終更新日2024-06-19
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Sequence differences between BAX and BAK core domains manifest as differences in their interactions with lipids.
Febs J., 291, 2024
4ZIG
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BU of 4zig by Molmil
Crystal Structure of core/latch dimer of Bax in complex with BidBH3mini
分子名称: Apoptosis regulator BAX, BH3-interacting domain death agonist
著者Robin, A.Y, Krishna Kumar, K, Westphal, D, Wardak, A.Z, Thompson, G.V, Dewson, G, Colman, P.M, Czabotar, P.E.
登録日2015-04-28
公開日2015-07-22
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystal structure of Bax bound to the BH3 peptide of Bim identifies important contacts for interaction.
Cell Death Dis, 6, 2015
4BD2
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BU of 4bd2 by Molmil
Bax domain swapped dimer in complex with BidBH3
分子名称: APOPTOSIS REGULATOR BAX, BH3-INTERACTING DOMAIN DEATH AGONIST
著者Czabotar, P.E, Westphal, D, Adams, J.M, Colman, P.M.
登録日2012-10-04
公開日2013-02-13
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (2.206 Å)
主引用文献Bax Crystal Structures Reveal How Bh3 Domains Activate Bax and Nucleate its Oligomerization to Induce Apoptosis.
Cell(Cambridge,Mass.), 152, 2013
7ADT
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BU of 7adt by Molmil
Orf virus Apoptosis inhibitor ORFV125
分子名称: 1,2-ETHANEDIOL, Apoptosis inhibitor, Apoptosis regulator BAX, ...
著者Suraweera, C.D, Hinds, M.G, Kvansakul, M.
登録日2020-09-16
公開日2021-10-06
最終更新日2024-06-19
実験手法X-RAY DIFFRACTION (2.210037 Å)
主引用文献Crystal structures of ORFV125 provide insight into orf virus-mediated inhibition of apoptosis.
Biochem.J., 477, 2020
4BD8
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BU of 4bd8 by Molmil
Bax domain swapped dimer induced by BimBH3 with CHAPS
分子名称: 1,2-ETHANEDIOL, APOPTOSIS REGULATOR BAX, PRASEODYMIUM ION
著者Czabotar, P.E, Westphal, D, Adams, J.M, Colman, P.M.
登録日2012-10-05
公開日2013-02-13
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (2.22 Å)
主引用文献Bax Crystal Structures Reveal How Bh3 Domains Activate Bax and Nucleate its Oligomerization to Induce Apoptosis.
Cell(Cambridge,Mass.), 152, 2013
8SVK
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BU of 8svk by Molmil
Crystal structure of Bax D71N core domain BH3-groove dimer
分子名称: Apoptosis regulator BAX, DI(HYDROXYETHYL)ETHER, SULFATE ION, ...
著者Miller, M.S, Czabotar, P.E, Colman, P.M.
登録日2023-05-16
公開日2023-12-27
最終更新日2024-06-19
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Sequence differences between BAX and BAK core domains manifest as differences in their interactions with lipids.
Febs J., 291, 2024
5W61
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BU of 5w61 by Molmil
Crystal structure of BAXP168G monomer co-crystallized with glycerol
分子名称: Apoptosis regulator BAX
著者Robin, A.Y, Colman, P.M, Czabotar, P.E.
登録日2017-06-16
公開日2018-06-27
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Ensemble Properties of Bax Determine Its Function.
Structure, 26, 2018
8SPE
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BU of 8spe by Molmil
Crystal structure of Bax core domain BH3-groove dimer - tetrameric fraction P31
分子名称: 1,2-ETHANEDIOL, Apoptosis regulator BAX, DI(HYDROXYETHYL)ETHER, ...
著者Miller, M.S, Cowan, A.D, Colman, P.M, Czabotar, P.E.
登録日2023-05-03
公開日2023-12-27
最終更新日2024-06-19
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Sequence differences between BAX and BAK core domains manifest as differences in their interactions with lipids.
Febs J., 291, 2024
2G5B
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BU of 2g5b by Molmil
Crystal Structure of the anti-Bax monoclonal antibody 6A7 and a Bax peptide.
分子名称: 2-acetamido-2-deoxy-alpha-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 6A7 Fab Heavy Chain, 6A7 Fab Light Chain, ...
著者Peyerl, F.W, Dai, S, Murphy, G.A, Marrack, P, Kappler, J.W.
登録日2006-02-22
公開日2006-07-25
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Elucidation of some Bax conformational changes through crystallization of an antibody-peptide complex.
Cell Death Differ., 14, 2007
8SPZ
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BU of 8spz by Molmil
Crystal structure of Bax core domain BH3-groove dimer - hexameric fraction with dioctanoyl phosphatidylserine
分子名称: Apoptosis regulator BAX, SULFATE ION
著者Cowan, A.D, Colman, P.M, Czabotar, P.E, Miller, M.S.
登録日2023-05-04
公開日2023-12-27
最終更新日2024-06-19
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Sequence differences between BAX and BAK core domains manifest as differences in their interactions with lipids.
Febs J., 291, 2024
8SRY
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BU of 8sry by Molmil
Crystal structure of BAK-BAX heterodimer with C12E8
分子名称: 2-(2-METHOXYETHOXY)ETHANOL, 3,6,9,12,15,18-HEXAOXAICOSANE-1,20-DIOL, 3,6,9,12,15-PENTAOXATRICOSAN-1-OL, ...
著者Brouwer, J.M, Czabotar, P.E, Colman, P.M, Miller, M.S.
登録日2023-05-08
公開日2023-12-27
最終更新日2024-06-19
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Sequence differences between BAX and BAK core domains manifest as differences in their interactions with lipids.
Febs J., 291, 2024
4ZIF
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BU of 4zif by Molmil
Crystal Structure of core/latch dimer of Bax in complex with BimBH3mini
分子名称: Apoptosis regulator BAX, Bcl-2-like protein 11
著者Robin, A.Y, Krishna Kumar, K, Westphal, D, Wardak, A.Z, Thompson, G.V, Dewson, G, Colman, P.M, Czabotar, P.E.
登録日2015-04-28
公開日2015-07-22
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.401 Å)
主引用文献Crystal structure of Bax bound to the BH3 peptide of Bim identifies important contacts for interaction.
Cell Death Dis, 6, 2015
3PK1
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BU of 3pk1 by Molmil
Crystal structure of Mcl-1 in complex with the BaxBH3 domain
分子名称: Apoptosis regulator BAX, CADMIUM ION, Induced myeloid leukemia cell differentiation protein Mcl-1
著者Czabotar, P.E, Colman, P.M.
登録日2010-11-11
公開日2010-12-29
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.486 Å)
主引用文献Mutation to Bax beyond the BH3 domain disrupts interactions with pro-survival proteins and promotes apoptosis
J.Biol.Chem., 286, 2011
4BD6
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BU of 4bd6 by Molmil
Bax domain swapped dimer in complex with BaxBH3
分子名称: APOPTOSIS REGULATOR BAX
著者Czabotar, P.E, Westphal, D, Adams, J.M, Colman, P.M.
登録日2012-10-05
公開日2013-02-13
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (2.494 Å)
主引用文献Bax Crystal Structures Reveal How Bh3 Domains Activate Bax and Nucleate its Oligomerization to Induce Apoptosis.
Cell(Cambridge,Mass.), 152, 2013
4ZIH
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BU of 4zih by Molmil
Crystal Structure of core/latch dimer of Bax in complex with BimBH3mini
分子名称: Apoptosis regulator BAX, Bcl-2-like protein 11
著者Robin, A.Y, Krishna Kumar, K, Westphal, D, Wardak, A.Z, Thompson, G.V, Dewson, G, Colman, P.M, Czabotar, P.E.
登録日2015-04-28
公開日2015-07-22
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Crystal structure of Bax bound to the BH3 peptide of Bim identifies important contacts for interaction.
Cell Death Dis, 6, 2015
5W5X
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BU of 5w5x by Molmil
Crystal structure of BAXP168G in complex with an activating antibody
分子名称: 1,2-ETHANEDIOL, 3C10 Fab' heavy chain, 3C10 Fab' light chain, ...
著者Robin, A.Y, Colman, P.M, Czabotar, P.E.
登録日2017-06-16
公開日2018-06-27
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.502 Å)
主引用文献Ensemble Properties of Bax Determine Its Function.
Structure, 26, 2018

 

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