4ZIH

Crystal Structure of core/latch dimer of Bax in complex with BimBH3mini

Summary for 4ZIH

Entry DOI	10.2210/pdb4zih/pdb
Related	4ZIE 4ZIF 4ZIG 4ZII
Descriptor	Apoptosis regulator BAX, Bcl-2-like protein 11 (3 entities in total)
Functional Keywords	bax, apoptosis, bh3 domain, structural genomics
Biological source	Homo sapiens (Human) More
Total number of polymer chains	2
Total formula weight	20856.62
Authors	Robin, A.Y.,Krishna Kumar, K.,Westphal, D.,Wardak, A.Z.,Thompson, G.V.,Dewson, G.,Colman, P.M.,Czabotar, P.E. (deposition date: 2015-04-28, release date: 2015-07-22, Last modification date: 2023-09-27)
Primary citation	Robin, A.Y.,Krishna Kumar, K.,Westphal, D.,Wardak, A.Z.,Thompson, G.V.,Dewson, G.,Colman, P.M.,Czabotar, P.E. Crystal structure of Bax bound to the BH3 peptide of Bim identifies important contacts for interaction. Cell Death Dis, 6:e1809-e1809, 2015 Cited by PubMed: 26158515 DOI: 10.1038/cddis.2015.141 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.5 Å)

Structure validation