4ZII
Crystal Structure of core/latch dimer of BaxI66A in complex with BidBH3
Summary for 4ZII
Entry DOI | 10.2210/pdb4zii/pdb |
Related | 4ZIE 4ZIF 4ZIG 4ZIH |
Descriptor | Apoptosis regulator BAX, BH3-interacting domain death agonist, 1,2-ETHANEDIOL, ... (4 entities in total) |
Functional Keywords | bax, apoptosis, bh3 domain, structural genomics |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 2 |
Total formula weight | 22826.82 |
Authors | Czabotar, P.E.,Robin, A.Y.,Krishna Kumar, K.,Westphal, D.,Wardak, A.Z.,Thompson, G.V.,Dewson, G.,Colman, P.M. (deposition date: 2015-04-28, release date: 2015-07-22, Last modification date: 2023-09-27) |
Primary citation | Robin, A.Y.,Krishna Kumar, K.,Westphal, D.,Wardak, A.Z.,Thompson, G.V.,Dewson, G.,Colman, P.M.,Czabotar, P.E. Crystal structure of Bax bound to the BH3 peptide of Bim identifies important contacts for interaction. Cell Death Dis, 6:e1809-e1809, 2015 Cited by PubMed: 26158515DOI: 10.1038/cddis.2015.141 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.191 Å) |
Structure validation
Download full validation report