4ZII
Crystal Structure of core/latch dimer of BaxI66A in complex with BidBH3
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Apoptosis regulator BAX | polymer | 170 | 18823.4 | 1 | UniProt (Q07812) Pfam (PF00452) | Homo sapiens (Human) | Bcl-2-like protein 4,Bcl2-L-4 |
| 2 | B (C) | BH3-interacting domain death agonist | polymer | 34 | 3693.1 | 1 | UniProt (P55957) | Homo sapiens | p22 BID,BID |
| 3 | C, D, E, F, G (A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 5 | Chemie (EDO) | |||
| 4 | H, I (A, C) | water | water | 18.0 | 53 | Chemie (HOH) |
Sequence modifications
A: 1 - 170 (UniProt: Q07812)
| PDB | External Database | Details |
|---|---|---|
| Ser 62 | Cys 62 | engineered mutation |
| Ser 126 | Cys 126 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 22516.5 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 310.3 | |
| All* | Total formula weight | 22826.8 |
