Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0042981 | biological_process | regulation of apoptotic process |
| C | 0005737 | cellular_component | cytoplasm |
| C | 0042981 | biological_process | regulation of apoptotic process |
| C | 0043065 | biological_process | positive regulation of apoptotic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | binding site for residue EDO A 201 |
| Chain | Residue |
| A | SER55 |
| A | THR56 |
| A | TRP158 |
| A | ASP159 |
| A | HOH303 |
| site_id | AC2 |
| Number of Residues | 3 |
| Details | binding site for residue EDO A 202 |
| Chain | Residue |
| A | MET20 |
| A | ARG145 |
| A | HOH309 |
| site_id | AC3 |
| Number of Residues | 1 |
| Details | binding site for residue EDO A 203 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | binding site for residue EDO A 204 |
| Chain | Residue |
| A | LEU45 |
| A | ALA81 |
| A | LYS123 |
| A | SER126 |
| A | HOH306 |
| site_id | AC5 |
| Number of Residues | 2 |
| Details | binding site for residue EDO A 205 |
| Chain | Residue |
| A | PRO88 |
| A | TRP139 |
Functional Information from PROSITE/UniProt
| site_id | PS01080 |
| Number of Residues | 20 |
| Details | BH1 Apoptosis regulator, Bcl-2 family BH1 motif signature. MFsDGnfNWGRVVALFyFAS |
| Chain | Residue | Details |
| A | MET99-SER118 | |
| site_id | PS01258 |
| Number of Residues | 12 |
| Details | BH2 Apoptosis regulator, Bcl-2 family BH2 motif signature. WIqdqGGWDgLL |
| Chain | Residue | Details |
| A | TRP151-LEU162 | |
| site_id | PS01259 |
| Number of Residues | 15 |
| Details | BH3 Apoptosis regulator, Bcl-2 family BH3 motif signature. IarhLAqVGDSMDRS |
| Chain | Residue | Details |
| C | ILE86-SER100 | |
| A | LEU59-ASN73 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 14 |
| Details | Motif: {"description":"BH3","evidences":[{"source":"PubMed","id":"8521816","evidenceCode":"ECO:0000269"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 20 |
| Details | Motif: {"description":"BH1"} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 15 |
| Details | Motif: {"description":"BH2"} |
| site_id | SWS_FT_FI4 |
| Number of Residues | 2 |
| Details | Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin)","evidences":[{"source":"PubMed","id":"36361894","evidenceCode":"ECO:0000269"}]} |
| site_id | SWS_FT_FI5 |
| Number of Residues | 1 |
| Details | Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"17525332","evidenceCode":"ECO:0007744"}]} |
