4ZIH
Crystal Structure of core/latch dimer of Bax in complex with BimBH3mini
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Apoptosis regulator BAX | polymer | 167 | 18364.8 | 1 | UniProt (Q07812) Pfam (PF00452) | Homo sapiens (Human) | Bcl-2-like protein 4,Bcl2-L-4 |
| 2 | B (B) | Bcl-2-like protein 11 | polymer | 20 | 2491.8 | 1 | UniProt (O43521) Pfam (PF08945) | Homo sapiens | Bcl2-L-11,Bcl2-interacting mediator of cell death |
| 3 | C, D (A, B) | water | water | 18.0 | 14 | Chemie (HOH) |
Sequence modifications
A: 1 - 164 (UniProt: Q07812)
| PDB | External Database | Details |
|---|---|---|
| Ser 62 | Cys 62 | engineered mutation |
| Ser 126 | Cys 126 | engineered mutation |
| Gly 165 | - | expression tag |
| Ser 166 | - | expression tag |
| Ser 167 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 20856.6 | |
| All* | Total formula weight | 20856.6 |
