5W5X

Crystal structure of BAXP168G in complex with an activating antibody

Summary for 5W5X

• Entry DOI: 10.2210/pdb5w5x/pdb
• Related: 5W5Z 5W60 5W61 5W62 5W63
• Descriptor: 3C10 Fab' light chain, 3C10 Fab' heavy chain, Apoptosis regulator BAX, ... (6 entities in total)
• Functional Keywords: fab', bax activation, unfolding, apoptosis, apoptosis-immune system complex, apoptosis/immune system
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 3
• Total formula weight: 70304.39

Authors

Robin, A.Y.,Colman, P.M.,Czabotar, P.E. (deposition date: 2017-06-16, release date: 2018-06-27, Last modification date: 2023-10-04)

• Primary citation: Robin, A.Y.,Iyer, S.,Birkinshaw, R.W.,Sandow, J.,Wardak, A.,Luo, C.S.,Shi, M.,Webb, A.I.,Czabotar, P.E.,Kluck, R.M.,Colman, P.M.; Ensemble Properties of Bax Determine Its Function.; Structure, 26:1346-, 2018; PubMed: 30122452; DOI: 10.1016/j.str.2018.07.006

Experimental method

X-RAY DIFFRACTION (2.502 Å)