5W5X
Crystal structure of BAXP168G in complex with an activating antibody
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (L) | 3C10 Fab' light chain | polymer | 213 | 23457.0 | 1 | Rattus norvegicus | ||
| 2 | B (H) | 3C10 Fab' heavy chain | polymer | 234 | 24917.0 | 1 | Rattus norvegicus | ||
| 3 | C (A) | Apoptosis regulator BAX | polymer | 194 | 21306.3 | 1 | UniProt (Q07812) Pfam (PF00452) | Homo sapiens (Human) | Bcl-2-like protein 4,Bcl2-L-4 |
| 4 | D, E, F, G, H... (L, H) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 9 | Chemie (EDO) | |||
| 5 | J (L) | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
| 6 | N, O, P (L, H, A) | water | water | 18.0 | 98 | Chemie (HOH) |
Sequence modifications
A: 1 - 192 (UniProt: Q07812)
| PDB | External Database | Details |
|---|---|---|
| Ser 62 | Cys 62 | engineered mutation |
| Ser 126 | Cys 126 | engineered mutation |
| Gly 168 | Pro 168 | engineered mutation |
| Ser 193 | - | expression tag |
| Ser 194 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 69680.4 | |
| Non-Polymers* | Number of molecules | 10 |
| Total formula weight | 624.0 | |
| All* | Total formula weight | 70304.4 |
