8SPZ
Crystal structure of Bax core domain BH3-groove dimer - hexameric fraction with dioctanoyl phosphatidylserine
Summary for 8SPZ
Entry DOI | 10.2210/pdb8spz/pdb |
Descriptor | Apoptosis regulator BAX, SULFATE ION (3 entities in total) |
Functional Keywords | bax, bcl2, apoptosis |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 4 |
Total formula weight | 36177.10 |
Authors | Cowan, A.D.,Colman, P.M.,Czabotar, P.E.,Miller, M.S. (deposition date: 2023-05-04, release date: 2023-12-27, Last modification date: 2024-06-19) |
Primary citation | Miller, M.S.,Cowan, A.D.,Brouwer, J.M.,Smyth, S.T.,Peng, L.,Wardak, A.Z.,Uren, R.T.,Luo, C.,Roy, M.J.,Shah, S.,Tan, Z.,Reid, G.E.,Colman, P.M.,Czabotar, P.E. Sequence differences between BAX and BAK core domains manifest as differences in their interactions with lipids. Febs J., 291:2335-2353, 2024 Cited by PubMed: 38088212DOI: 10.1111/febs.17031 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.4 Å) |
Structure validation
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