5OC9
 
 | | Crystal Structure of human TMEM16K / Anoctamin 10 | | 分子名称: | (2R)-2,3-dihydroxypropyl (7Z)-hexadec-7-enoate, Anoctamin-10, CALCIUM ION | | 著者 | Bushell, S.R, Pike, A.C.W, Chu, A, Tessitore, A, Rotty, B, Mukhopadhyay, S, Kupinska, K, Shrestha, L, Borkowska, O, Chalk, R, Burgess-Brown, N.A, Love, J, Edwards, A.M, Arrowsmith, C.H, Bountra, C, Carpenter, E.P, Structural Genomics Consortium (SGC) | | 登録日 | 2017-06-29 | | 公開日 | 2018-07-25 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | | 主引用文献 | The structural basis of lipid scrambling and inactivation in the endoplasmic reticulum scramblase TMEM16K.
Nat Commun, 10, 2019
|
|
6R7X
 | | CryoEM structure of calcium-bound human TMEM16K / Anoctamin 10 in detergent (2mM Ca2+, closed form) | | 分子名称: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, Anoctamin-10, CALCIUM ION, ... | | 著者 | Pike, A.C.W, Bushell, S.R, Shintre, C.A, Tessitore, A, Baronina, A, Chu, A, Mukhopadhyay, S, Shrestha, L, Chalk, R, Burgess-Brown, N.A, Love, J, Huiskonen, J.T, Edwards, A.M, Arrowsmith, C.H, Bountra, C, Carpenter, E.P, Structural Genomics Consortium (SGC) | | 登録日 | 2019-03-29 | | 公開日 | 2019-05-01 | | 最終更新日 | 2024-05-22 | | 実験手法 | ELECTRON MICROSCOPY (3.47 Å) | | 主引用文献 | The structural basis of lipid scrambling and inactivation in the endoplasmic reticulum scramblase TMEM16K.
Nat Commun, 10, 2019
|
|
6R7Y
 | | CryoEM structure of calcium-bound human TMEM16K / Anoctamin 10 in detergent (low Ca2+, closed form) | | 分子名称: | Anoctamin-10, CALCIUM ION | | 著者 | Pike, A.C.W, Bushell, S.R, Shintre, C.A, Tessitore, A, Chu, A, Mukhopadhyay, S, Shrestha, L, Chalk, R, Burgess-Brown, N.A, Love, J, Huiskonen, J.T, Edwards, A.M, Arrowsmith, C.H, Bountra, C, Carpenter, E.P, Structural Genomics Consortium (SGC) | | 登録日 | 2019-03-29 | | 公開日 | 2019-05-01 | | 最終更新日 | 2024-05-22 | | 実験手法 | ELECTRON MICROSCOPY (4.2 Å) | | 主引用文献 | The structural basis of lipid scrambling and inactivation in the endoplasmic reticulum scramblase TMEM16K.
Nat Commun, 10, 2019
|
|
6R65
 | | Crystal Structure of human TMEM16K / Anoctamin 10 (Form 2) | | 分子名称: | Anoctamin-10, CALCIUM ION | | 著者 | Bushell, S.R, Pike, A.C.W, Chu, A, Tessitore, A, Rotty, B, Mukhopadhyay, S, Kupinska, K, Shrestha, L, Borkowska, O, Chalk, R, Burgess-Brown, N.A, Love, J, Edwards, A.M, Arrowsmith, C.H, Bountra, C, Carpenter, E.P, Structural Genomics Consortium (SGC) | | 登録日 | 2019-03-26 | | 公開日 | 2019-05-01 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | | 主引用文献 | The structural basis of lipid scrambling and inactivation in the endoplasmic reticulum scramblase TMEM16K.
Nat Commun, 10, 2019
|
|
6R7Z
 | | CryoEM structure of calcium-free human TMEM16K / Anoctamin 10 in detergent (closed form) | | 分子名称: | Anoctamin-10 | | 著者 | Pike, A.C.W, Bushell, S.R, Shintre, C.A, Tessitore, A, Chu, A, Mukhopadhyay, S, Shrestha, L, Chalk, R, Burgess-Brown, N.A, Love, J, Huiskonen, J.T, Edwards, A.M, Arrowsmith, C.H, Bountra, C, Carpenter, E.P, Structural Genomics Consortium (SGC) | | 登録日 | 2019-03-29 | | 公開日 | 2019-05-01 | | 最終更新日 | 2024-05-22 | | 実験手法 | ELECTRON MICROSCOPY (5.14 Å) | | 主引用文献 | The structural basis of lipid scrambling and inactivation in the endoplasmic reticulum scramblase TMEM16K.
Nat Commun, 10, 2019
|
|
5OYG
 | | Structure of calcium-free mTMEM16A chloride channel at 4.06 A resolution | | 分子名称: | Anoctamin-1 | | 著者 | Paulino, C, Kalienkova, V, Lam, K.M, Neldner, Y, Dutzler, R. | | 登録日 | 2017-09-08 | | 公開日 | 2017-12-20 | | 最終更新日 | 2019-12-11 | | 実験手法 | ELECTRON MICROSCOPY (4.06 Å) | | 主引用文献 | Activation mechanism of the calcium-activated chloride channel TMEM16A revealed by cryo-EM.
Nature, 552, 2017
|
|
4WIT
 | | TMEM16 lipid scramblase in crystal form 2 | | 分子名称: | CALCIUM ION, Predicted protein | | 著者 | Dutzler, R, Brunner, J.D, Lim, N.K, Schenck, S. | | 登録日 | 2014-09-26 | | 公開日 | 2014-11-12 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (3.4 Å) | | 主引用文献 | X-ray structure of a calcium-activated TMEM16 lipid scramblase.
Nature, 516, 2014
|
|
4WIS
 | | Crystal structure of the lipid scramblase nhTMEM16 in crystal form 1 | | 分子名称: | CALCIUM ION, lipid scramblase | | 著者 | Dutzler, R, Brunner, J.D, Lim, N.K, Schenck, S. | | 登録日 | 2014-09-26 | | 公開日 | 2014-11-12 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | | 主引用文献 | X-ray structure of a calcium-activated TMEM16 lipid scramblase.
Nature, 516, 2014
|
|
6BGJ
 | | Cryo-EM structure of the TMEM16A calcium-activated chloride channel in LMNG | | 分子名称: | Anoctamin-1, CALCIUM ION | | 著者 | Dang, S, Feng, S, Tien, J, Peters, C.J, Bulkley, D, Lolicato, M, Zhao, J, Zuberbuhler, K, Ye, W, Qi, L, Chen, T, Craik, C.S, Jan, Y.N, Minor Jr, D.L, Cheng, Y, Jan, L.Y. | | 登録日 | 2017-10-28 | | 公開日 | 2017-12-27 | | 最終更新日 | 2024-03-13 | | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | | 主引用文献 | Cryo-EM structures of the TMEM16A calcium-activated chloride channel.
Nature, 552, 2017
|
|
6BGI
 | | Cryo-EM structure of the TMEM16A calcium-activated chloride channel in nanodisc | | 分子名称: | Anoctamin-1, CALCIUM ION | | 著者 | Dang, S, Feng, S, Tien, J, Peters, C.J, Bulkley, D, Lolicato, M, Zhao, J, Zuberbuhler, K, Ye, W, Qi, J, Chen, T, Craik, C.S, Jan, Y.N, Minor Jr, D.L, Cheng, Y, Jan, L.Y. | | 登録日 | 2017-10-28 | | 公開日 | 2017-12-27 | | 最終更新日 | 2024-03-13 | | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | | 主引用文献 | Cryo-EM structures of the TMEM16A calcium-activated chloride channel.
Nature, 552, 2017
|
|
6E1O
 | |
6E0H
 | |
6DZ7
 | |
5NL2
 | | cryo-EM structure of the mTMEM16A ion channel at 6.6 A resolution. | | 分子名称: | Anoctamin-1 | | 著者 | Paulino, C, Neldner, Y, Lam, K.M, Kalienkova, V, Brunner, J.D, Schenck, S, Dutzler, R. | | 登録日 | 2017-04-03 | | 公開日 | 2017-06-07 | | 最終更新日 | 2024-05-15 | | 実験手法 | ELECTRON MICROSCOPY (6.6 Å) | | 主引用文献 | Structural basis for anion conduction in the calcium-activated chloride channel TMEM16A.
Elife, 6, 2017
|
|
7B5D
 | |
7B5C
 | | Structure of calcium-bound mTMEM16A(ac) chloride channel at 3.7 A resolution | | 分子名称: | Anoctamin-1, CALCIUM ION | | 著者 | Lam, A.K.M, Rheinberger, J, Paulino, C, Dutzler, R. | | 登録日 | 2020-12-03 | | 公開日 | 2021-02-10 | | 最終更新日 | 2021-02-17 | | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | | 主引用文献 | Gating the pore of the calcium-activated chloride channel TMEM16A.
Nat Commun, 12, 2021
|
|
7B5E
 | | Structure of calcium-bound mTMEM16A(ac)-I551A chloride channel at 4.1 A resolution | | 分子名称: | Anoctamin-1, CALCIUM ION | | 著者 | Lam, A.K.M, Rheinberger, J, Paulino, C, Dutzler, R. | | 登録日 | 2020-12-03 | | 公開日 | 2021-02-10 | | 最終更新日 | 2021-02-17 | | 実験手法 | ELECTRON MICROSCOPY (4.1 Å) | | 主引用文献 | Gating the pore of the calcium-activated chloride channel TMEM16A.
Nat Commun, 12, 2021
|
|
5OYB
 | | Structure of calcium-bound mTMEM16A chloride channel at 3.75 A resolution | | 分子名称: | Anoctamin-1, CALCIUM ION | | 著者 | Paulino, C, Kalienkova, V, Lam, K.M, Neldner, Y, Dutzler, R. | | 登録日 | 2017-09-08 | | 公開日 | 2017-12-20 | | 最終更新日 | 2019-12-11 | | 実験手法 | ELECTRON MICROSCOPY (3.75 Å) | | 主引用文献 | Activation mechanism of the calcium-activated chloride channel TMEM16A revealed by cryo-EM.
Nature, 552, 2017
|
|
7RXG
 | |
7RX2
 | |
7RXA
 | |
7RXH
 | |
7RWJ
 | |
7RXB
 | |
7RX3
 | |
