5OYB

Structure of calcium-bound mTMEM16A chloride channel at 3.75 A resolution

Summary for 5OYB

• Entry DOI: 10.2210/pdb5oyb/pdb
• Related: 5OYG
• EMDB information: 3860 3861
• Descriptor: Anoctamin-1, CALCIUM ION (2 entities in total)
• Functional Keywords: tmem16 family, ion channel, membrane protein, cryo-em
• Biological source: Mus musculus (Mouse)
• Total number of polymer chains: 2
• Total formula weight: 222278.30

Authors

Paulino, C.,Kalienkova, V.,Lam, K.M.,Neldner, Y.,Dutzler, R. (deposition date: 2017-09-08, release date: 2017-12-20, Last modification date: 2019-12-11)

• Primary citation: Paulino, C.,Kalienkova, V.,Lam, A.K.M.,Neldner, Y.,Dutzler, R.; Activation mechanism of the calcium-activated chloride channel TMEM16A revealed by cryo-EM.; Nature, 552:421-425, 2017; PubMed: 29236691; DOI: 10.1038/nature24652

Experimental method

ELECTRON MICROSCOPY (3.75 Å)