5OC9
Crystal Structure of human TMEM16K / Anoctamin 10
Summary for 5OC9
Entry DOI | 10.2210/pdb5oc9/pdb |
Descriptor | Anoctamin-10, CALCIUM ION, (2R)-2,3-dihydroxypropyl (7Z)-hexadec-7-enoate, ... (4 entities in total) |
Functional Keywords | membrane protein, calcium activation, transport protein, lipid transport, structural genomics, structural genomics consortium, sgc |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 2 |
Total formula weight | 160745.34 |
Authors | Bushell, S.R.,Pike, A.C.W.,Chu, A.,Tessitore, A.,Rotty, B.,Mukhopadhyay, S.,Kupinska, K.,Shrestha, L.,Borkowska, O.,Chalk, R.,Burgess-Brown, N.A.,Love, J.,Edwards, A.M.,Arrowsmith, C.H.,Bountra, C.,Carpenter, E.P.,Structural Genomics Consortium (SGC) (deposition date: 2017-06-29, release date: 2018-07-25, Last modification date: 2024-01-17) |
Primary citation | Bushell, S.R.,Pike, A.C.W.,Falzone, M.E.,Rorsman, N.J.G.,Ta, C.M.,Corey, R.A.,Newport, T.D.,Christianson, J.C.,Scofano, L.F.,Shintre, C.A.,Tessitore, A.,Chu, A.,Wang, Q.,Shrestha, L.,Mukhopadhyay, S.M.M.,Love, J.D.,Burgess-Brown, N.A.,Sitsapesan, R.,Stansfeld, P.J.,Huiskonen, J.T.,Tammaro, P.,Accardi, A.,Carpenter, E.P. The structural basis of lipid scrambling and inactivation in the endoplasmic reticulum scramblase TMEM16K. Nat Commun, 10:3956-3956, 2019 Cited by PubMed: 31477691DOI: 10.1038/s41467-019-11753-1 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.2 Å) |
Structure validation
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