5N82
 
 | | Crystal structure of an engineered TycA variant in complex with an beta-Phe-AMP analog | | Descriptor: | 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, SULFATE ION, Tyrocidine synthase 1, ... | | Authors: | Niquille, D.L, Hansen, D.L, Mori, T, Fercher, D, Kries, H, Hilvert, D. | | Deposit date: | 2017-02-22 | | Release date: | 2017-12-13 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (1.708 Å) | | Cite: | Nonribosomal biosynthesis of backbone-modified peptides.
Nat Chem, 10, 2018
|
|
4UUN
 | |
7NPX
 | | Thioredoxin glutathione reductase from Schistosoma mansoni in complex with 3-(3-Methoxyquinoxalin-2-yl)propanoic acid at 24 hours of soaking | | Descriptor: | 3-(3-methoxyquinoxalin-2-yl)propanoic acid, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ... | | Authors: | Fata, F, Silvestri, I, Williams, D.L, Angelucci, F. | | Deposit date: | 2021-02-28 | | Release date: | 2021-05-19 | | Last modified: | 2024-01-31 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Probing the Surface of a Parasite Drug Target Thioredoxin Glutathione Reductase Using Small Molecule Fragments.
Acs Infect Dis., 7, 2021
|
|
3DFV
 | | Adjacent GATA DNA binding | | Descriptor: | DNA (5'-D(*DAP*DAP*DGP*DCP*DAP*DGP*DAP*DTP*DAP*DAP*DGP*DTP*DCP*DTP*DTP*DAP*DTP*DCP*DAP*DG)-3'), DNA (5'-D(*DTP*DTP*DCP*DTP*DGP*DAP*DTP*DAP*DAP*DGP*DAP*DCP*DTP*DTP*DAP*DTP*DCP*DTP*DGP*DC)-3'), Trans-acting T-cell-specific transcription factor GATA-3, ... | | Authors: | Bates, D.L, Kim, G.K, Guo, L, Chen, L. | | Deposit date: | 2008-06-12 | | Release date: | 2008-07-29 | | Last modified: | 2017-10-25 | | Method: | X-RAY DIFFRACTION (3.1 Å) | | Cite: | Crystal structures of multiple GATA zinc fingers bound to DNA reveal new insights into DNA recognition and self-association by GATA.
J.Mol.Biol., 381, 2008
|
|
4UUO
 | |
6S6L
 | | Cryo-EM structure of murine norovirus (MNV-1) | | Descriptor: | Capsid protein | | Authors: | Snowden, J.S, Hurdiss, D.L, Adeyemi, O.O, Ranson, N.A, Herod, M.R, Stonehouse, N.J. | | Deposit date: | 2019-07-03 | | Release date: | 2020-05-13 | | Last modified: | 2024-05-22 | | Method: | ELECTRON MICROSCOPY (3.1 Å) | | Cite: | Dynamics in the murine norovirus capsid revealed by high-resolution cryo-EM.
Plos Biol., 18, 2020
|
|
4GOW
 | | Crystal Structure of Ca2+/CaM:Kv7.4 (KCNQ4) B helix complex | | Descriptor: | CALCIUM ION, Calmodulin, Potassium voltage-gated channel subfamily KQT member 4 | | Authors: | Xu, Q, Chang, A, Tolia, A, Minor Jr, D.L. | | Deposit date: | 2012-08-20 | | Release date: | 2012-12-12 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Structure of a Ca(2+)/CaM:Kv7.4 (KCNQ4) B-helix complex provides insight into M current modulation.
J.Mol.Biol., 425, 2013
|
|
6LNI
 | | Cryo-EM structure of amyloid fibril formed by full-length human prion protein | | Descriptor: | Major prion protein | | Authors: | Wang, L.Q, Zhao, K, Yuan, H.Y, Wang, Q, Guan, Z.Y, Tao, J, Li, X.N, Hao, M.M, Chen, J, Zhang, D.L, Zhu, H.L, Yin, P, Liu, C, Liang, Y. | | Deposit date: | 2019-12-30 | | Release date: | 2020-06-10 | | Last modified: | 2020-06-24 | | Method: | ELECTRON MICROSCOPY (2.702 Å) | | Cite: | Cryo-EM structure of an amyloid fibril formed by full-length human prion protein.
Nat.Struct.Mol.Biol., 27, 2020
|
|
2GUI
 | | Structure and Function of Cyclized Versions of the Proofreading Exonuclease Subunit of E. coli DNA Polymerase III | | Descriptor: | 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, DNA polymerase III epsilon subunit, ... | | Authors: | Park, A.Y, Carr, P.D, Ollis, D.L, Dixon, N.E. | | Deposit date: | 2006-04-30 | | Release date: | 2007-03-13 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | Structure and Function of Cyclized Versions of the Proofreading Exonuclease Subunit E. coli DNA Polymerase III
To be Published
|
|
2WYH
 | | Structure of the Streptococcus pyogenes family GH38 alpha-mannosidase | | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ALPHA-MANNOSIDASE, GLYCEROL, ... | | Authors: | Suits, M.D.L, Zhu, Y, Taylor, E.J, Zechel, D.L, Gilbert, H.J, Davies, G.J. | | Deposit date: | 2009-11-16 | | Release date: | 2010-02-16 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Structure and Kinetic Investigation of Streptococcus Pyogenes Family Gh38 Alpha-Mannosidase
Plos One, 5, 2010
|
|
2WYI
 | | Structure of the Streptococcus pyogenes family GH38 alpha-mannosidase complexed with swainsonine | | Descriptor: | 1S-8AB-OCTAHYDRO-INDOLIZIDINE-1A,2A,8B-TRIOL, 2-(2-METHOXYETHOXY)ETHANOL, ALPHA-MANNOSIDASE, ... | | Authors: | Suits, M.D.L, Zhu, Y, Taylor, E.J, Zechel, D.L, Gilbert, H.J, Davies, G.J. | | Deposit date: | 2009-11-16 | | Release date: | 2010-02-16 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Structure and Kinetic Investigation of Streptococcus Pyogenes Family Gh38 Alpha-Mannosidase
Plos One, 5, 2010
|
|
2RC6
 | | Refined structure of FNR from Leptospira interrogans bound to NADP+ | | Descriptor: | FLAVIN-ADENINE DINUCLEOTIDE, Ferredoxin-NADP reductase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... | | Authors: | Nascimento, A.S, Catalano-Dupuy, D.L, Ceccarelli, E.A, Polikarpov, I. | | Deposit date: | 2007-09-19 | | Release date: | 2008-03-25 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Crystal structures of Leptospira interrogans FAD-containing ferredoxin-NADP+ reductase and its complex with NADP+.
Bmc Struct.Biol., 7, 2007
|
|
5HK6
 | |
5HKD
 | | Bacterial sodium channel neck 7G mutant | | Descriptor: | CALCIUM ION, Ion transport protein | | Authors: | Rohaim, A, Minor, D.L. | | Deposit date: | 2016-01-13 | | Release date: | 2016-03-09 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (3.8 Å) | | Cite: | Unfolding of a Temperature-Sensitive Domain Controls Voltage-Gated Channel Activation.
Cell, 164, 2016
|
|
6DFK
 | | Crystal structure of the 11S subunit of the Plasmodium falciparum proteasome, PA28 | | Descriptor: | SULFATE ION, Subunit of proteaseome activator complex,putative | | Authors: | Xie, S.C, Metcalfe, R.D, Gillett, D.L, Tilley, L, Griffin, M.D.W. | | Deposit date: | 2018-05-15 | | Release date: | 2019-08-07 | | Last modified: | 2023-10-11 | | Method: | X-RAY DIFFRACTION (3.1 Å) | | Cite: | The structure of the PA28-20S proteasome complex from Plasmodium falciparum and implications for proteostasis.
Nat Microbiol, 4, 2019
|
|
7DFV
 | | Cryo-EM structure of plant NLR RPP1 tetramer core part | | Descriptor: | NAD+ hydrolase (NADase) | | Authors: | Ma, S.C, Lapin, D, Liu, L, Sun, Y, Song, W, Zhang, X.X, Logemann, E, Yu, D.L, Wang, J, Jirschitzka, J, Han, Z.F, SchulzeLefert, P, Parker, J.E, Chai, J.J. | | Deposit date: | 2020-11-10 | | Release date: | 2020-12-16 | | Last modified: | 2024-03-27 | | Method: | ELECTRON MICROSCOPY (2.99 Å) | | Cite: | Direct pathogen-induced assembly of an NLR immune receptor complex to form a holoenzyme.
Science, 370, 2020
|
|
7S9Z
 | | Helicobacter Hepaticus CcsBA Closed Conformation | | Descriptor: | Cytochrome c biogenesis protein, HEME B/C, PHOSPHATIDYLETHANOLAMINE | | Authors: | Mendez, D.L, Lowder, E.P, Tillman, D.E, Sutherland, M.C, Collier, A.L, Rau, M.J, Fitzpatrick, J.A, Kranz, R.G. | | Deposit date: | 2021-09-21 | | Release date: | 2021-12-22 | | Last modified: | 2022-01-12 | | Method: | ELECTRON MICROSCOPY (4.14 Å) | | Cite: | Cryo-EM of CcsBA reveals the basis for cytochrome c biogenesis and heme transport.
Nat.Chem.Biol., 18, 2022
|
|
7S9Y
 | | Helicobacter Hepaticus CcsBA Open Conformation | | Descriptor: | Cytochrome c biogenesis protein, HEME B/C, PHOSPHATIDYLETHANOLAMINE | | Authors: | Mendez, D.L, Lowder, E.P, Tillman, D.E, Sutherland, M.C, Collier, A.L, Rau, M.J, Fitzpatrick, J.A, Kranz, R.G. | | Deposit date: | 2021-09-21 | | Release date: | 2021-12-22 | | Last modified: | 2024-06-05 | | Method: | ELECTRON MICROSCOPY (3.56 Å) | | Cite: | Cryo-EM of CcsBA reveals the basis for cytochrome c biogenesis and heme transport.
Nat.Chem.Biol., 18, 2022
|
|
5W97
 | | Crystal Structure of CO-bound Cytochrome c Oxidase determined by Serial Femtosecond X-Ray Crystallography at Room Temperature | | Descriptor: | (1R)-2-{[{[(2S)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL (11E)-OCTADEC-11-ENOATE, (1S)-2-{[(2-AMINOETHOXY)(HYDROXY)PHOSPHORYL]OXY}-1-[(STEAROYLOXY)METHYL]ETHYL (5E,8E,11E,14E)-ICOSA-5,8,11,14-TETRAENOATE, (7R,17E,20E)-4-HYDROXY-N,N,N-TRIMETHYL-9-OXO-7-[(PALMITOYLOXY)METHYL]-3,5,8-TRIOXA-4-PHOSPHAHEXACOSA-17,20-DIEN-1-AMINIUM 4-OXIDE, ... | | Authors: | Rousseau, D.L, Yeh, S.-R, Ishigami, I, Zatsepin, N.A, Grant, T.D, Fromme, P, Fromme, R. | | Deposit date: | 2017-06-22 | | Release date: | 2017-08-09 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Crystal structure of CO-bound cytochrome c oxidase determined by serial femtosecond X-ray crystallography at room temperature.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
|
|
3MFM
 | | Crystal Structures and Mutational Analyses of Acyl-CoA Carboxylase Subunit of Streptomyces coelicolor | | Descriptor: | Propionyl-CoA carboxylase complex B subunit | | Authors: | Diacovich, L, Arabolaza, A, Shillito, E.M, Lin, T.-W, Mitchell, D.L, Melgar, M.M. | | Deposit date: | 2010-04-02 | | Release date: | 2010-10-13 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (2.38 Å) | | Cite: | Crystal structures and mutational analyses of acyl-CoA carboxylase beta subunit of Streptomyces coelicolor.
Biochemistry, 49, 2010
|
|
3MJ4
 | | Crystal structure of UDP-galactopyranose mutase in complex with phosphonate analog of UDP-galactopyranose | | Descriptor: | (((2S,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)methyl)phosphonic (((2R,3S,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl phosphoric) anhydride, FLAVIN-ADENINE DINUCLEOTIDE, GLYCEROL, ... | | Authors: | Karunan Partha, S, Sadeghi-Khomami, A, Slowski, K, Kotake, T, Thomas, N.R, Jakeman, D.L, Sanders, D.A.R. | | Deposit date: | 2010-04-12 | | Release date: | 2010-10-20 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (2.65 Å) | | Cite: | Chemoenzymatic Synthesis, Inhibition Studies, and X-ray Crystallographic Analysis of the Phosphono Analog of UDP-Galp as an Inhibitor and Mechanistic Probe for UDP-Galactopyranose Mutase.
J.Mol.Biol., 403, 2010
|
|
6E3Y
 | | Cryo-EM structure of the active, Gs-protein complexed, human CGRP receptor | | Descriptor: | Calcitonin gene-related peptide 1, Calcitonin gene-related peptide type 1 receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | | Authors: | Liang, Y.L, Khoshouei, M, Deganutti, G, Glukhova, A, Koole, C, Peat, T.S, Radjainia, M, Plitzko, J.M, Baumeister, W, Miller, L.J, Hay, D.L, Christopoulos, A, Reynolds, C.A, Wootten, D, Sexton, P.M. | | Deposit date: | 2018-07-16 | | Release date: | 2018-09-19 | | Last modified: | 2020-01-15 | | Method: | ELECTRON MICROSCOPY (3.3 Å) | | Cite: | Cryo-EM structure of the active, Gs-protein complexed, human CGRP receptor.
Nature, 561, 2018
|
|
7DRV
 | | Structural basis of SARS-CoV-2-closely-related bat coronavirus RaTG13 to hACE2 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme 2, ... | | Authors: | Liu, K.F, Pan, X.Q, Li, L.J, Feng, Y, Meng, Y.M, Zhang, Y.F, Wu, L.L, Chen, Q, Zheng, A.Q, Song, C.L, Jia, Y.F, Niu, S, Qiao, C.P, Zhao, X, Ma, D.L, Ma, X.P, Tan, S.G, Qi, J.X, Gao, G.F, Wang, Q.H. | | Deposit date: | 2020-12-29 | | Release date: | 2021-08-25 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (3.09 Å) | | Cite: | Binding and molecular basis of the bat coronavirus RaTG13 virus to ACE2 in humans and other species.
Cell, 184, 2021
|
|
5WBF
 | | Double CACHE (dCACHE) sensing domain of TlpC chemoreceptor from Helicobacter pylori | | Descriptor: | GLYCEROL, LACTIC ACID, Methyl-accepting chemotaxis transducer (TlpC) | | Authors: | Machuca, M.A, Johnson, K.S, Liu, Y.C, Steer, D.L, Ottemann, K.M, Roujeinikova, A. | | Deposit date: | 2017-06-28 | | Release date: | 2017-11-08 | | Last modified: | 2023-11-15 | | Method: | X-RAY DIFFRACTION (2.19 Å) | | Cite: | Helicobacter pylori chemoreceptor TlpC mediates chemotaxis to lactate.
Sci Rep, 7, 2017
|
|
2RN1
 | | Liquid crystal solution structure of the kissing complex formed by the apical loop of the HIV TAR RNA and a high affinity RNA aptamer optimized by SELEX | | Descriptor: | RNA (5'-R(P*GP*AP*GP*CP*CP*CP*UP*GP*GP*GP*AP*GP*GP*CP*UP*C)-3'), RNA (5'-R(P*GP*CP*UP*GP*GP*UP*CP*CP*CP*AP*GP*AP*CP*AP*GP*C)-3') | | Authors: | Van Melckebeke, H, Devany, M, Di Primo, C, Beaurain, F, Toulme, J, Bryce, D.L, Boisbouvier, J. | | Deposit date: | 2007-12-05 | | Release date: | 2008-09-23 | | Last modified: | 2024-05-01 | | Method: | SOLUTION NMR | | Cite: | Liquid-crystal NMR structure of HIV TAR RNA bound to its SELEX RNA aptamer reveals the origins of the high stability of the complex
Proc.Natl.Acad.Sci.Usa, 105, 2008
|
|
