2RN1

Liquid crystal solution structure of the kissing complex formed by the apical loop of the HIV TAR RNA and a high affinity RNA aptamer optimized by SELEX

Summary for 2RN1

• Entry DOI: 10.2210/pdb2rn1/pdb
• Related: 1KIS
• NMR Information: BMRB: 11014
• Descriptor: RNA (5'-R(P*GP*AP*GP*CP*CP*CP*UP*GP*GP*GP*AP*GP*GP*CP*UP*C)-3'), RNA (5'-R(P*GP*CP*UP*GP*GP*UP*CP*CP*CP*AP*GP*AP*CP*AP*GP*C)-3') (2 entities in total)
• Functional Keywords: rna kissing complex, hiv tar, high affinity rna aptamer selected by selex, liquid crystal nmr, ga base pair, rna
• Total number of polymer chains: 2
• Total formula weight: 10280.25

Authors

Van Melckebeke, H.,Devany, M.,Di Primo, C.,Beaurain, F.,Toulme, J.,Bryce, D.L.,Boisbouvier, J. (deposition date: 2007-12-05, release date: 2008-09-23, Last modification date: 2024-05-01)

• Primary citation: Van Melckebeke, H.,Devany, M.,Di Primo, C.,Beaurain, F.,Bryce, D.L.,Boisbouvier, J.; Liquid-crystal NMR structure of HIV TAR RNA bound to its SELEX RNA aptamer reveals the origins of the high stability of the complex; Proc.Natl.Acad.Sci.Usa, 105:9210-9215, 2008; PubMed: 18607001; DOI: 10.1073/pnas.0712121105

Experimental method

SOLUTION NMR