2P1H
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2p1h by Molmil](/molmil-images/mine/2p1h) | Rapid Folding and Unfolding of Apaf-1 CARD | 分子名称: | Apoptotic protease-activating factor 1, ZINC ION | 著者 | Milam, S.L, Nicely, N.I, Feeney, B, Mattos, C, Clark, A.C. | 登録日 | 2007-03-05 | 公開日 | 2007-05-15 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.59 Å) | 主引用文献 | Rapid Folding and Unfolding of Apaf-1 CARD. J.Mol.Biol., 369, 2007
|
|
3YGS
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3ygs by Molmil](/molmil-images/mine/3ygs) | APAF-1 CARD IN COMPLEX WITH PRODOMAIN OF PROCASPASE-9 | 分子名称: | APOPTOTIC PROTEASE ACTIVATING FACTOR 1, PROCASPASE 9 | 著者 | Qin, H, Srinivasula, S, Wu, G, Fernandes-Alnemri, T, Alnemri, E, Shi, Y. | 登録日 | 1999-05-08 | 公開日 | 2000-04-19 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Structural basis of procaspase-9 recruitment by the apoptotic protease-activating factor 1. Nature, 399, 1999
|
|
4E9M
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4e9m by Molmil](/molmil-images/mine/4e9m) | |
4UZ0
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4uz0 by Molmil](/molmil-images/mine/4uz0) | Crystal Structure of apoptosis repressor with CARD (ARC) | 分子名称: | GLYCEROL, NUCLEOLAR PROTEIN 3 | 著者 | Kim, S.H, Jeong, J.H, Jang, T.H, Kim, Y.G, Park, H.H. | 登録日 | 2014-09-04 | 公開日 | 2015-07-01 | 最終更新日 | 2017-07-12 | 実験手法 | X-RAY DIFFRACTION (2.399 Å) | 主引用文献 | Crystal Structure of Caspase Recruiting Domain (Card) of Apoptosis Repressor with Card (Arc) and its Implication in Inhibition of Apoptosis. Sci.Rep., 5, 2015
|
|
6XKK
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6xkk by Molmil](/molmil-images/mine/6xkk) | Cryo-EM structure of the NLRP1-CARD filament | 分子名称: | NACHT, LRR and PYD domains-containing protein 1 | 著者 | Hollingsworth, L.R, David, L, Li, Y, Sharif, H, Fontana, P, Fu, T, Wu, H. | 登録日 | 2020-06-26 | 公開日 | 2020-11-25 | 最終更新日 | 2024-03-06 | 実験手法 | ELECTRON MICROSCOPY (3.72 Å) | 主引用文献 | Mechanism of filament formation in UPA-promoted CARD8 and NLRP1 inflammasomes. Nat Commun, 12, 2021
|
|
4RHW
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4rhw by Molmil](/molmil-images/mine/4rhw) | Crystal structure of Apaf-1 CARD and caspase-9 CARD complex | 分子名称: | Apoptotic protease-activating factor 1, CHLORIDE ION, Caspase-9, ... | 著者 | Hu, Q, Wu, D, Yan, C, Shi, Y. | 登録日 | 2014-10-03 | 公開日 | 2014-10-15 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Molecular determinants of caspase-9 activation by the Apaf-1 apoptosome. Proc. Natl. Acad. Sci. U.S.A., 111, 2014
|
|
8XQK
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8xqk by Molmil](/molmil-images/mine/8xqk) | The Crystal Structure of Apaf from Biortus. | 分子名称: | Apoptotic protease-activating factor 1, PHOSPHATE ION | 著者 | Wang, F, Cheng, W, Lv, Z, Ju, C, Ni, C. | 登録日 | 2024-01-05 | 公開日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (2.85 Å) | 主引用文献 | The Crystal Structure of Apaf from Biortus. To Be Published
|
|
3CRD
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3crd by Molmil](/molmil-images/mine/3crd) | NMR STRUCTURE OF THE RAIDD CARD DOMAIN, 15 STRUCTURES | 分子名称: | RAIDD | 著者 | Chou, J.J, Matsuo, H, Duan, H, Wagner, G. | 登録日 | 1998-07-24 | 公開日 | 1999-02-02 | 最終更新日 | 2024-05-22 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution structure of the RAIDD CARD and model for CARD/CARD interaction in caspase-2 and caspase-9 recruitment. Cell(Cambridge,Mass.), 94, 1998
|
|
6BZE
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6bze by Molmil](/molmil-images/mine/6bze) | Cryo-EM structure of BCL10 CARD filament | 分子名称: | B-cell lymphoma/leukemia 10 | 著者 | David, L, Li, Y, Ma, J, Garner, E, Zhang, X, Wu, H. | 登録日 | 2017-12-23 | 公開日 | 2018-02-14 | 最終更新日 | 2024-03-13 | 実験手法 | ELECTRON MICROSCOPY (4 Å) | 主引用文献 | Assembly mechanism of the CARMA1-BCL10-MALT1-TRAF6 signalosome. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
|
|
2YGS
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2ygs by Molmil](/molmil-images/mine/2ygs) | CARD DOMAIN FROM APAF-1 | 分子名称: | APOPTOTIC PROTEASE ACTIVATING FACTOR 1 | 著者 | Shi, Y. | 登録日 | 1999-05-08 | 公開日 | 2000-04-19 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Structural basis of procaspase-9 recruitment by the apoptotic protease-activating factor 1. Nature, 399, 1999
|
|
6E27
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6e27 by Molmil](/molmil-images/mine/6e27) | The CARD9 CARD domain-swapped dimer with a zinc ion bound to one of the two zinc binding sites | 分子名称: | Caspase recruitment domain-containing protein 9, ZINC ION | 著者 | Holliday, M.J, Ferrao, R, Boenig, G, Deuber, E.C, Fairbrother, W.J. | 登録日 | 2018-07-10 | 公開日 | 2018-09-26 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (1.811 Å) | 主引用文献 | Picomolar zinc binding modulates formation of Bcl10-nucleating assemblies of the caspase recruitment domain (CARD) of CARD9. J. Biol. Chem., 293, 2018
|
|
6E28
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6e28 by Molmil](/molmil-images/mine/6e28) | The CARD9 CARD domain-swapped dimer | 分子名称: | Caspase recruitment domain-containing protein 9 | 著者 | Holliday, M.J, Ferrao, R, Boenig, G, Deuber, E.C, Fairbrother, W.J. | 登録日 | 2018-07-10 | 公開日 | 2018-09-26 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.36 Å) | 主引用文献 | Picomolar zinc binding modulates formation of Bcl10-nucleating assemblies of the caspase recruitment domain (CARD) of CARD9. J. Biol. Chem., 293, 2018
|
|
8CZO
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8czo by Molmil](/molmil-images/mine/8czo) | Cryo-EM structure of BCL10 CARD - MALT1 DD filament | 分子名称: | B-cell lymphoma/leukemia 10, Mucosa-associated lymphoid tissue lymphoma translocation protein 1 | 著者 | David, L, Wu, H. | 登録日 | 2022-05-25 | 公開日 | 2022-06-22 | 最終更新日 | 2022-08-17 | 実験手法 | ELECTRON MICROSCOPY (4.3 Å) | 主引用文献 | BCL10 Mutations Define Distinct Dependencies Guiding Precision Therapy for DLBCL. Cancer Discov, 12, 2022
|
|
8CZD
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8czd by Molmil](/molmil-images/mine/8czd) | Cryo-EM structure of BCL10 R58Q filament | 分子名称: | B-cell lymphoma/leukemia 10 | 著者 | David, L, Wu, H. | 登録日 | 2022-05-24 | 公開日 | 2022-06-22 | 最終更新日 | 2024-02-14 | 実験手法 | ELECTRON MICROSCOPY (4.6 Å) | 主引用文献 | BCL10 Mutations Define Distinct Dependencies Guiding Precision Therapy for DLBCL. Cancer Discov, 12, 2022
|
|
7KEU
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7keu by Molmil](/molmil-images/mine/7keu) | Cryo-EM structure of the Caspase-1-CARD:ASC-CARD octamer | 分子名称: | Apoptosis-associated speck-like protein containing a CARD, Caspase-1 | 著者 | Hollingsworth, L.R, David, L, Li, Y, Ruan, J, Wu, H. | 登録日 | 2020-10-12 | 公開日 | 2020-11-25 | 最終更新日 | 2024-03-06 | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | 主引用文献 | Mechanism of filament formation in UPA-promoted CARD8 and NLRP1 inflammasomes. Nat Commun, 12, 2021
|
|
5YRN
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5yrn by Molmil](/molmil-images/mine/5yrn) | Structure of RIP2 CARD domain | 分子名称: | Receptor-interacting serine/threonine-protein kinase 2 | 著者 | Wu, B, Gong, Q. | 登録日 | 2017-11-09 | 公開日 | 2018-11-14 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (4.1 Å) | 主引用文献 | Structural basis of RIP2 activation and signaling. Nat Commun, 9, 2018
|
|
5WVC
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5wvc by Molmil](/molmil-images/mine/5wvc) | Structure of the CARD-CARD disk | 分子名称: | Apoptotic protease-activating factor 1, Caspase, IODIDE ION | 著者 | Lin, S.C, Lo, Y.C, Su, T.W. | 登録日 | 2016-12-24 | 公開日 | 2017-04-19 | 実験手法 | X-RAY DIFFRACTION (2.993 Å) | 主引用文献 | Structural Insights into DD-Fold Assembly and Caspase-9 Activation by the Apaf-1 Apoptosome. Structure, 25, 2017
|
|
3KAT
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3kat by Molmil](/molmil-images/mine/3kat) | Crystal Structure of the CARD domain of the human NLRP1 protein, Northeast Structural Genomics Consortium Target HR3486E | 分子名称: | NACHT, LRR and PYD domains-containing protein 1 | 著者 | Forouhar, F, Abashidze, M, Seetharaman, J, Mao, M, Xiao, R, Ciccosanti, C, Shastry, R, Everett, J.K, Nair, R, Acton, T.B, Rost, B, Montelione, G.T, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG) | 登録日 | 2009-10-19 | 公開日 | 2009-10-27 | 最終更新日 | 2019-07-17 | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | 主引用文献 | Northeast Structural Genomics Consortium Target HR3486E To be Published
|
|
5H8O
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5h8o by Molmil](/molmil-images/mine/5h8o) | Crystal structure of an ASC-binding nanobody in complex with the CARD domain of ASC | 分子名称: | Apoptosis-associated speck-like protein containing a CARD, VHH nanobody | 著者 | Lu, A, Schmidt, F.I, Ruan, J, Tang, C, Wu, H, Ploegh, H.L. | 登録日 | 2015-12-23 | 公開日 | 2016-04-06 | 最終更新日 | 2016-05-18 | 実験手法 | X-RAY DIFFRACTION (4.206 Å) | 主引用文献 | A single domain antibody fragment that recognizes the adaptor ASC defines the role of ASC domains in inflammasome assembly. J.Exp.Med., 213, 2016
|
|
6XKJ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6xkj by Molmil](/molmil-images/mine/6xkj) | Cryo-EM structure of CARD8-CARD filament | 分子名称: | Caspase recruitment domain-containing protein 8 | 著者 | Hollingsworth, L.R, David, L, Li, Y, Sharif, H, Fontana, P, Fu, T, Wu, H. | 登録日 | 2020-06-26 | 公開日 | 2020-11-25 | 最終更新日 | 2024-03-06 | 実験手法 | ELECTRON MICROSCOPY (3.54 Å) | 主引用文献 | Mechanism of filament formation in UPA-promoted CARD8 and NLRP1 inflammasomes. Nat Commun, 12, 2021
|
|
5FNA
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5fna by Molmil](/molmil-images/mine/5fna) | Cryo-EM reconstruction of caspase-1 CARD | 分子名称: | Caspase-1 | 著者 | Li, Y, Lu, A, Schmidt, F.I, Yin, Q, Chen, S, Fu, T.M, Tong, A.B, Ploegh, H.L, Mao, Y, Wu, H. | 登録日 | 2015-11-11 | 公開日 | 2016-03-30 | 最終更新日 | 2024-05-08 | 実験手法 | ELECTRON MICROSCOPY (4.8 Å) | 主引用文献 | Molecular Basis of Caspase-1 Polymerization and its Inhibition by a Novel Capping Mechanism Nat.Struct.Mol.Biol., 23, 2016
|
|
1C15
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1c15 by Molmil](/molmil-images/mine/1c15) | SOLUTION STRUCTURE OF APAF-1 CARD | 分子名称: | APOPTOTIC PROTEASE ACTIVATING FACTOR 1 | 著者 | Zhou, P, Chou, J, Olea, R.S, Yuan, J, Wagner, G. | 登録日 | 1999-07-20 | 公開日 | 1999-09-20 | 最終更新日 | 2024-05-22 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution structure of Apaf-1 CARD and its interaction with caspase-9 CARD: a structural basis for specific adaptor/caspase interaction. Proc.Natl.Acad.Sci.USA, 96, 1999
|
|
1DGN
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1dgn by Molmil](/molmil-images/mine/1dgn) | SOLUTION STRUCTURE OF ICEBERG, AN INHIBITOR OF INTERLEUKIN-1BETA GENERATION | 分子名称: | ICEBERG (PROTEASE INHIBITOR) | 著者 | Humke, E.W, Shriver, S.K, Starovasnik, M.A, Fairbrother, W.J, Dixit, V.M. | 登録日 | 1999-11-24 | 公開日 | 2000-10-09 | 最終更新日 | 2024-05-22 | 実験手法 | SOLUTION NMR | 主引用文献 | ICEBERG: a novel inhibitor of interleukin-1beta generation. Cell(Cambridge,Mass.), 103, 2000
|
|
2B1W
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2b1w by Molmil](/molmil-images/mine/2b1w) | |
1CWW
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1cww by Molmil](/molmil-images/mine/1cww) | SOLUTION STRUCTURE OF THE CASPASE RECRUITMENT DOMAIN (CARD) FROM APAF-1 | 分子名称: | APOPTOTIC PROTEASE ACTIVATING FACTOR 1 | 著者 | Day, C.L, Dupont, C, Lackmann, M, Vaux, D.L, Hinds, M.G. | 登録日 | 1999-08-26 | 公開日 | 2000-01-21 | 最終更新日 | 2024-05-22 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution structure and mutagenesis of the caspase recruitment domain (CARD) from Apaf-1. Cell Death Differ., 6, 1999
|
|