4RHW

Crystal structure of Apaf-1 CARD and caspase-9 CARD complex

Descriptor	Apoptotic protease-activating factor 1, Caspase-9, SULFATE ION, ... (5 entities in total)
Functional Keywords	death domain superfamily, apoptosis
Biological source	Homo sapiens (human)
Total number of polymer chains	6
Total molecular weight	70625.29
Authors	Hu, Q.,Wu, D.,Yan, C.,Shi, Y. (deposition date: 2014-10-03, release date: 2014-10-15, Last modification date: 2018-10-17)
Primary citation	Hu, Q.,Wu, D.,Chen, W.,Yan, Z.,Yan, C.,He, T.,Liang, Q.,Shi, Y. Molecular determinants of caspase-9 activation by the Apaf-1 apoptosome. Proc. Natl. Acad. Sci. U.S.A., 111:16254-16261, 2014 PubMed: 25313070 (PDB entries with the same primary citation) DOI: 10.1073/pnas.1418000111 Import into Mendeley
Experimental method	X-RAY DIFFRACTION (2.1 Å)

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