3YGS

APAF-1 CARD IN COMPLEX WITH PRODOMAIN OF PROCASPASE-9

Summary for 3YGS

• Entry DOI: 10.2210/pdb3ygs/pdb
• Related: 2YGS
• Descriptor: APOPTOTIC PROTEASE ACTIVATING FACTOR 1, PROCASPASE 9 (3 entities in total)
• Functional Keywords: apoptosis, caspase activation, caspase recruitment, recognition complex
• Biological source: Homo sapiens (human); More
• Cellular location: Cytoplasm: O14727
• Total number of polymer chains: 2
• Total formula weight: 22238.46

Authors

Qin, H.,Srinivasula, S.,Wu, G.,Fernandes-Alnemri, T.,Alnemri, E.,Shi, Y. (deposition date: 1999-05-08, release date: 2000-04-19, Last modification date: 2023-12-27)

• Primary citation: Qin, H.,Srinivasula, S.M.,Wu, G.,Fernandes-Alnemri, T.,Alnemri, E.S.,Shi, Y.; Structural basis of procaspase-9 recruitment by the apoptotic protease-activating factor 1.; Nature, 399:549-557, 1999; PubMed: 10376594; DOI: 10.1038/21124

Experimental method

X-RAY DIFFRACTION (2.5 Å)