3YGS
APAF-1 CARD IN COMPLEX WITH PRODOMAIN OF PROCASPASE-9
Summary for 3YGS
Entry DOI | 10.2210/pdb3ygs/pdb |
Related | 2YGS |
Descriptor | APOPTOTIC PROTEASE ACTIVATING FACTOR 1, PROCASPASE 9 (3 entities in total) |
Functional Keywords | apoptosis, caspase activation, caspase recruitment, recognition complex |
Biological source | Homo sapiens (human) More |
Cellular location | Cytoplasm: O14727 |
Total number of polymer chains | 2 |
Total formula weight | 22238.46 |
Authors | Qin, H.,Srinivasula, S.,Wu, G.,Fernandes-Alnemri, T.,Alnemri, E.,Shi, Y. (deposition date: 1999-05-08, release date: 2000-04-19, Last modification date: 2023-12-27) |
Primary citation | Qin, H.,Srinivasula, S.M.,Wu, G.,Fernandes-Alnemri, T.,Alnemri, E.S.,Shi, Y. Structural basis of procaspase-9 recruitment by the apoptotic protease-activating factor 1. Nature, 399:549-557, 1999 Cited by PubMed: 10376594DOI: 10.1038/21124 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.5 Å) |
Structure validation
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