Loading
PDBj
English日本語简体中文繁體中文한국어
✖
ﾒﾆｭｰPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help
PDB: 142 件
6SF1
DownloadVisualize
BU of 6sf1 by Molmil
Bone morphogenetic protein 10 (BMP10) complexed with extracellular domain of activin receptor-like kinase 1 (ALK1).
分子名称: Bone morphogenetic protein 10, NICKEL (II) ION, Serine/threonine-protein kinase receptor R3
著者Salmon, R.M, Guo, J, Yu, M, Li, W.
登録日2019-07-30
公開日2020-04-08
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Molecular basis of ALK1-mediated signalling by BMP9/BMP10 and their prodomain-bound forms.
Nat Commun, 11, 2020
2ASK
DownloadVisualize
BU of 2ask by Molmil
Structure of human Artemin
分子名称: SULFATE ION, artemin
著者Silvian, L, Jin, P, Carmillo, P, Boriack-Sjodin, P.A, Pelletier, C, Rushe, M, Gong, B.J, Sah, D, Pepinsky, B, Rossomando, A.
登録日2005-08-23
公開日2006-06-13
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Artemin crystal structure reveals insights into heparan sulfate binding.
Biochemistry, 45, 2006
2BHK
DownloadVisualize
BU of 2bhk by Molmil
Crystal structure of human growth and differentiation factor 5 (GDF5)
分子名称: GROWTH DIFFERENTIATION FACTOR 5, ISOPROPYL ALCOHOL
著者Schreuder, H, Liesum, A, Pohl, J, Kruse, M, Koyama, M.
登録日2005-01-12
公開日2005-03-11
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Crystal Structure of Recombinant Human Growth Differentiation Factor 5. Evidence for Interaction of the Type I and Type II Receptor Binding Sites.
Biochem.Biophys.Res.Commun., 329, 2005
8E3G
DownloadVisualize
BU of 8e3g by Molmil
BMP2/GDF5 heterodimer
分子名称: Bone morphogenetic protein 2, GLYCEROL, Growth/differentiation factor 5
著者Gipson, G.R, Nolan, K.T, Thompson, T.B.
登録日2022-08-17
公開日2023-02-15
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Formation and characterization of BMP2/GDF5 and BMP4/GDF5 heterodimers.
Bmc Biol., 21, 2023
5TX6
DownloadVisualize
BU of 5tx6 by Molmil
Structure of TGF-beta2 derivative with deletion of residues 52-71 and 10 single amino acid mutations (mmTGF-beta2-7M)
分子名称: CALCIUM ION, Transforming growth factor beta-2
著者Petrunak, E.M, Hinck, A.P.
登録日2016-11-15
公開日2017-03-01
最終更新日2019-12-04
実験手法X-RAY DIFFRACTION (2.746 Å)
主引用文献An engineered transforming growth factor beta (TGF-beta ) monomer that functions as a dominant negative to block TGF-beta signaling.
J. Biol. Chem., 292, 2017
5TX2
DownloadVisualize
BU of 5tx2 by Molmil
Miniature TGF-beta2 3-mutant monomer
分子名称: Transforming growth factor beta-2
著者Taylor, A.B, Kim, S.K, Hart, P.J, Hinck, A.P.
登録日2016-11-15
公開日2017-03-01
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.82 Å)
主引用文献An engineered transforming growth factor beta (TGF-beta ) monomer that functions as a dominant negative to block TGF-beta signaling.
J. Biol. Chem., 292, 2017
5UHM
DownloadVisualize
BU of 5uhm by Molmil
Apo-Structure of Mature Growth Differentiation Factor 11
分子名称: Growth/differentiation factor 11
著者Goebel, E, Thompson, T.
登録日2017-01-11
公開日2017-03-22
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural basis for potency differences between GDF8 and GDF11.
BMC Biol., 15, 2017
5MR9
DownloadVisualize
BU of 5mr9 by Molmil
Ligand-receptor complex.
分子名称: Neurturin
著者Sandmark, J, Oster, L, Aagaard, A, Roth, R.G, Dahl, G.
登録日2016-12-21
公開日2018-01-17
最終更新日2019-10-16
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structure and biophysical characterisation of the human complex - a role for heparan sulfate
To Be Published
2GYR
DownloadVisualize
BU of 2gyr by Molmil
Crystal structure of human artemin
分子名称: Neurotrophic factor artemin, isoform 3
著者Wang, X.Q.
登録日2006-05-09
公開日2006-06-27
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structure of Artemin Complexed with Its Receptor GFRalpha3: Convergent Recognition of Glial Cell Line-Derived Neurotrophic Factors.
Structure, 14, 2006
6OMN
DownloadVisualize
BU of 6omn by Molmil
Glycosylated BMP2 homodimer
分子名称: Bone morphogenetic protein 2, alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose
著者Juo, Z.S, Seeherman, H.
登録日2019-04-19
公開日2019-05-08
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.68 Å)
主引用文献A BMP/activin A chimera is superior to native BMPs and induces bone repair in nonhuman primates when delivered in a composite matrix.
Sci Transl Med, 11, 2019
2GYZ
DownloadVisualize
BU of 2gyz by Molmil
Crystal structure of human artemin
分子名称: neurotrophic factor artemin isoform 3
著者Wang, X.Q, Garcia, K.C.
登録日2006-05-10
公開日2006-06-27
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.76 Å)
主引用文献Structure of Artemin Complexed with Its Receptor GFRalpha3: Convergent Recognition of Glial Cell Line-Derived Neurotrophic Factors.
Structure, 14, 2006
5NMZ
DownloadVisualize
BU of 5nmz by Molmil
human Neurturin (97-197)
分子名称: GLYCEROL, Neurturin
著者Bigalke, J.M, Sandmark, J, Roth, R.
登録日2017-04-07
公開日2018-02-14
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Structure and biophysical characterization of the human full-length neurturin-GFRa2 complex: A role for heparan sulfate in signaling.
J. Biol. Chem., 293, 2018
1KLA
DownloadVisualize
BU of 1kla by Molmil
SOLUTION STRUCTURE OF TGF-B1, NMR, MODELS 1-17 OF 33 STRUCTURES
分子名称: TRANSFORMING GROWTH FACTOR-BETA 1
著者Hinck, A.P, Archer, S.J, Qian, S.W, Roberts, A.B, Sporn, M.B, Weatherbee, J.A, Tsang, M.L.-S, Lucas, R, Zhang, B.-L, Wenker, J, Torchia, D.A.
登録日1996-01-16
公開日1996-08-17
最終更新日2017-11-29
実験手法SOLUTION NMR
主引用文献Transforming growth factor beta 1: three-dimensional structure in solution and comparison with the X-ray structure of transforming growth factor beta 2.
Biochemistry, 35, 1996
1KLC
DownloadVisualize
BU of 1klc by Molmil
SOLUTION STRUCTURE OF TGF-B1, NMR, MINIMIZED AVERAGE STRUCTURE
分子名称: TRANSFORMING GROWTH FACTOR-BETA 1
著者Hinck, A.P, Archer, S.J, Qian, S.W, Roberts, A.B, Sporn, M.B, Weatherbee, J.A, Tsang, M.L.-S, Lucas, R, Zhang, B.-L, Wenker, J, Torchia, D.A.
登録日1996-01-16
公開日1996-08-17
最終更新日2017-11-29
実験手法SOLUTION NMR
主引用文献Transforming growth factor beta 1: three-dimensional structure in solution and comparison with the X-ray structure of transforming growth factor beta 2.
Biochemistry, 35, 1996
1KLD
DownloadVisualize
BU of 1kld by Molmil
SOLUTION STRUCTURE OF TGF-B1, NMR, MODELS 18-33 OF 33 STRUCTURES
分子名称: TRANSFORMING GROWTH FACTOR-BETA 1
著者Hinck, A.P, Archer, S.J, Qian, S.W, Roberts, A.B, Sporn, M.B, Weatherbee, J.A, Tsang, M.L.-S, Lucas, R, Zhang, B.-L, Wenker, J, Torchia, D.A.
登録日1996-01-16
公開日1996-08-17
最終更新日2017-11-29
実験手法SOLUTION NMR
主引用文献Transforming growth factor beta 1: three-dimensional structure in solution and comparison with the X-ray structure of transforming growth factor beta 2.
Biochemistry, 35, 1996
1LXI
DownloadVisualize
BU of 1lxi by Molmil
Refinement of BMP7 crystal structure
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, BONE MORPHOGENETIC PROTEIN 7
著者Greenwald, J, Groppe, J, Kwiatkowski, W, Choe, S.
登録日2002-06-05
公開日2003-04-01
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献The BMP7/ActRII Extracellular Domain Complex Provides New Insights into the Cooperative Nature of Receptor Assembly
Mol.Cell, 11, 2003
1REU
DownloadVisualize
BU of 1reu by Molmil
Structure of the bone morphogenetic protein 2 mutant L51P
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, bone morphogenetic protein 2
著者Keller, S, Nickel, J, Zhang, J.-L, Sebald, W, Mueller, T.D.
登録日2003-11-07
公開日2004-05-04
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.65 Å)
主引用文献Molecular recognition of BMP-2 and BMP receptor IA.
Nat.Struct.Mol.Biol., 11, 2004
1TGK
DownloadVisualize
BU of 1tgk by Molmil
HUMAN TRANSFORMING GROWTH FACTOR BETA 3, CRYSTALLIZED FROM PEG 4000
分子名称: TRANSFORMING GROWTH FACTOR BETA 3
著者Mittl, P.R.E, Priestle, J.P, Gruetter, M.G.
登録日1996-07-10
公開日1997-03-12
最終更新日2018-04-18
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献The crystal structure of TGF-beta 3 and comparison to TGF-beta 2: implications for receptor binding.
Protein Sci., 5, 1996
1TFG
DownloadVisualize
BU of 1tfg by Molmil
AN UNUSUAL FEATURE REVEALED BY THE CRYSTAL STRUCTURE AT 2.2 ANGSTROMS RESOLUTION OF HUMAN TRANSFORMING GROWTH FACTOR-BETA2
分子名称: TRANSFORMING GROWTH FACTOR, BETA 2
著者Gruetter, M, Schlunegger, M.
登録日1992-11-17
公開日1993-10-31
最終更新日2019-08-14
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献An unusual feature revealed by the crystal structure at 2.2 A resolution of human transforming growth factor-beta 2.
Nature, 358, 1992
1TGJ
DownloadVisualize
BU of 1tgj by Molmil
HUMAN TRANSFORMING GROWTH FACTOR-BETA 3, CRYSTALLIZED FROM DIOXANE
分子名称: 1,4-DIETHYLENE DIOXIDE, TRANSFORMING GROWTH FACTOR-BETA 3
著者Mittl, P.R.E, Priestle, J.P, Gruetter, M.G.
登録日1996-07-09
公開日1997-01-11
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献The crystal structure of TGF-beta 3 and comparison to TGF-beta 2: implications for receptor binding.
Protein Sci., 5, 1996
5E4G
DownloadVisualize
BU of 5e4g by Molmil
Crystal structure of human growth differentiation factor 11 (GDF-11)
分子名称: Growth/differentiation factor 11, TETRAETHYLENE GLYCOL
著者Padyana, A.K, Vaidialingam, B, Hayes, D.B, Gupta, P, Franti, M, Farrow, N.A.
登録日2015-10-06
公開日2016-03-09
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Crystal structure of human GDF11.
Acta Crystallogr.,Sect.F, 72, 2016
5F3H
DownloadVisualize
BU of 5f3h by Molmil
Structure of myostatin in complex with humanized RK35 antibody
分子名称: Growth/differentiation factor 8, humanized RK35 antibody heavy chain, humanized RK35 antibody light chain
著者Parris, K.D, Mosyak, L.
登録日2015-12-02
公開日2016-09-28
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Beyond CDR-grafting: Structure-guided humanization of framework and CDR regions of an anti-myostatin antibody.
Mabs, 8, 2016
5F3B
DownloadVisualize
BU of 5f3b by Molmil
Structure of myostatin in complex with chimeric RK35 antibody
分子名称: GLYCEROL, Growth/differentiation factor 8, RK35 Chimeric antibody heavy chain, ...
著者Parris, K.D, Mosyak, L.
登録日2015-12-02
公開日2016-09-28
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.76 Å)
主引用文献Beyond CDR-grafting: Structure-guided humanization of framework and CDR regions of an anti-myostatin antibody.
Mabs, 8, 2016
5I05
DownloadVisualize
BU of 5i05 by Molmil
Crystal structure of human BMP9 at 1.87 A resolution
分子名称: GLYCEROL, Growth/differentiation factor 2
著者Saito, T, Bokhove, M, Jovine, L.
登録日2016-02-03
公開日2017-06-07
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.87 Å)
主引用文献Structural Basis of the Human Endoglin-BMP9 Interaction: Insights into BMP Signaling and HHT1.
Cell Rep, 19, 2017
2QCQ
DownloadVisualize
BU of 2qcq by Molmil
Crystal structure of Bone Morphogenetic Protein-3 (BMP-3)
分子名称: Bone morphogenetic protein 3
著者Allendorph, G.P.
登録日2007-06-19
公開日2007-10-23
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.21 Å)
主引用文献BMP-3 and BMP-6 Structures Illuminate the Nature of Binding Specificity with Receptors.
Biochemistry, 46, 2007

220472

件を2024-05-29に公開中

PDB statisticsPDBj update infoContact PDBjnumon