5UHM

Apo-Structure of Mature Growth Differentiation Factor 11

Summary for 5UHM

Entry DOI	10.2210/pdb5uhm/pdb
Descriptor	Growth/differentiation factor 11 (2 entities in total)
Functional Keywords	tgfb gdf11 apo activin, signaling protein
Biological source	Homo sapiens (Human)
Cellular location	Secreted : O95390
Total number of polymer chains	2
Total formula weight	24942.62
Authors	Goebel, E.,Thompson, T. (deposition date: 2017-01-11, release date: 2017-03-22, Last modification date: 2023-10-04)
Primary citation	Walker, R.G.,Czepnik, M.,Goebel, E.J.,McCoy, J.C.,Vujic, A.,Cho, M.,Oh, J.,Aykul, S.,Walton, K.L.,Schang, G.,Bernard, D.J.,Hinck, A.P.,Harrison, C.A.,Martinez-Hackert, E.,Wagers, A.J.,Lee, R.T.,Thompson, T.B. Structural basis for potency differences between GDF8 and GDF11. BMC Biol., 15:19-19, 2017 Cited by PubMed: 28257634 DOI: 10.1186/s12915-017-0350-1 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.9 Å)

Structure validation