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PDB: 3 results

5UHM
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BU of 5uhm by Molmil
Apo-Structure of Mature Growth Differentiation Factor 11
Descriptor: Growth/differentiation factor 11
Authors:Goebel, E, Thompson, T.
Deposit date:2017-01-11
Release date:2017-03-22
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural basis for potency differences between GDF8 and GDF11.
BMC Biol., 15, 2017
6MAC
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BU of 6mac by Molmil
Ternary structure of GDF11 bound to ActRIIB-ECD and Alk5-ECD
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Activin receptor type-2B, Growth/differentiation factor 11, ...
Authors:Goebel, E.J, Thompson, T.B.
Deposit date:2018-08-27
Release date:2019-07-17
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.34 Å)
Cite:Structural characterization of an activin class ternary receptor complex reveals a third paradigm for receptor specificity.
Proc.Natl.Acad.Sci.USA, 116, 2019
7MRZ
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BU of 7mrz by Molmil
Structure of GDF11 bound to fused ActRIIB-ECD and Alk4-ECD with Anti-ActRIIB Fab fragment
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Activin receptor type-2B,Activin receptor type-1B, Fab Heavy Chain, ...
Authors:Goebel, E.J, Kattamuri, C, Gipson, G.R, Thompson, T.B.
Deposit date:2021-05-10
Release date:2022-01-19
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structures of activin ligand traps using natural sets of type I and type II TGF beta receptors.
Iscience, 25, 2022

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