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PDB: 42 件
7BAH
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BU of 7bah by Molmil
Structure of RIG-I CTD bound to OH-RNA
分子名称: Antiviral innate immune response receptor RIG-I, RNA (5'-R(*GP*AP*CP*GP*CP*UP*AP*GP*CP*GP*UP*C)-3'), ZINC ION
著者Anand, K, Hagelueken, G, Fusshoeller, D, Geyer, M.
登録日2020-12-15
公開日2022-01-12
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.89 Å)
主引用文献A conserved isoleucine in the RNA sensor RIG-I controls immune tolerance to mitochondrial RNA
To Be Published
7MK1
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BU of 7mk1 by Molmil
Structure of a protein-modified aptamer complex
分子名称: Antiviral innate immune response receptor RIG-I, DNA (41-MER), MAGNESIUM ION, ...
著者Ren, X, Pyle, A.M.
登録日2021-04-21
公開日2021-11-03
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Evolving A RIG-I Antagonist: A Modified DNA Aptamer Mimics Viral RNA.
J.Mol.Biol., 433, 2021
3LRR
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BU of 3lrr by Molmil
Crystal structure of human RIG-I CTD bound to a 12 bp AU rich 5' ppp dsRNA
分子名称: Probable ATP-dependent RNA helicase DDX58, RNA (5'-R(*(ATP)P*UP*AP*UP*AP*UP*AP*UP*AP*UP*AP*U)-3'), ZINC ION
著者Li, P.
登録日2010-02-11
公開日2010-06-02
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献The Structural Basis of 5' Triphosphate Double-Stranded RNA Recognition by RIG-I C-Terminal Domain.
Structure, 18, 2010
3OG8
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BU of 3og8 by Molmil
Crystal structure of human RIG-I CTD bound to a 14-bp blunt-ended dsRNA
分子名称: Antiviral innate immune response receptor RIG-I, RNA (5'-R(*GP*GP*CP*GP*CP*GP*CP*GP*CP*GP*CP*GP*CP*C)-3'), ZINC ION
著者Li, P.
登録日2010-08-16
公開日2010-11-03
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Crystal structure of RIG-I C-terminal domain bound to blunt-ended double-strand RNA without 5' triphosphate.
Nucleic Acids Res., 39, 2011
3ZD7
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BU of 3zd7 by Molmil
Snapshot 3 of RIG-I scanning on RNA duplex
分子名称: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, PROBABLE ATP-DEPENDENT RNA HELICASE DDX58, ...
著者Luo, D, Pyle, A.M.
登録日2012-11-25
公開日2013-08-07
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Defining the Functional Determinants for RNA Surveillance by Rig-I.
Embo Rep., 14, 2013
2YKG
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BU of 2ykg by Molmil
Structural insights into RNA recognition by RIG-I
分子名称: 5'-R(*GP*CP*GP*CP*GP*CP*GP*CP*GP*CP)-3', PROBABLE ATP-DEPENDENT RNA HELICASE DDX58, SULFATE ION, ...
著者Luo, D, Pyle, A.M.
登録日2011-05-27
公開日2011-10-26
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structural Insights Into RNA Recognition by Rig-I.
Cell(Cambridge,Mass.), 147, 2011
3NCU
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BU of 3ncu by Molmil
Structural and functional insights into pattern recognition by the innate immune receptor RIG-I
分子名称: 5'-R(*(GDP)P*AP*CP*GP*CP*UP*AP*GP*CP*GP*UP*C)-3', RIG-I, ZINC ION
著者Sheng, G, Li, H.
登録日2010-06-05
公開日2010-06-30
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.55 Å)
主引用文献Structural and functional insights into 5'-ppp RNA pattern recognition by the innate immune receptor RIG-I.
Nat.Struct.Mol.Biol., 17, 2010
4BPB
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BU of 4bpb by Molmil
STRUCTURAL INSIGHTS INTO RNA RECOGNITION BY RIG-I
分子名称: 5'-R(*GP*CP*GP*CP*GP*CP*GP*CP*GP*CP)-3', PROBABLE ATP-DEPENDENT RNA HELICASE DDX58, SULFATE ION, ...
著者Luo, D, Pyle, A.M.
登録日2013-05-23
公開日2013-06-19
実験手法X-RAY DIFFRACTION (2.584 Å)
主引用文献Structural Insights Into RNA Recognition by Rig-I.
Cell(Cambridge,Mass.), 147, 2011
3LRN
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BU of 3lrn by Molmil
Crystal structure of human RIG-I CTD bound to a 14 bp GC 5' ppp dsRNA
分子名称: Probable ATP-dependent RNA helicase DDX58, RNA (5'-R(*(GTP)P*GP*CP*GP*CP*GP*CP*GP*CP*GP*CP*GP*CP*C)-3'), ZINC ION
著者Li, P.
登録日2010-02-11
公開日2010-06-02
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献The Structural Basis of 5' Triphosphate Double-Stranded RNA Recognition by RIG-I C-Terminal Domain.
Structure, 18, 2010
5F9F
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BU of 5f9f by Molmil
Crystal structure of RIG-I helicase-RD in complex with 24-mer blunt-end hairpin RNA
分子名称: (R,R)-2,3-BUTANEDIOL, MAGNESIUM ION, Probable ATP-dependent RNA helicase DDX58, ...
著者Wang, C, Marcotrigiano, J, Miller, M.T, Jiang, F.
登録日2015-12-09
公開日2016-01-13
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.601 Å)
主引用文献Structural basis for m7G recognition and 2'-O-methyl discrimination in capped RNAs by the innate immune receptor RIG-I.
Proc.Natl.Acad.Sci.USA, 113, 2016
2QFD
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BU of 2qfd by Molmil
Crystal structure of the regulatory domain of human RIG-I with bound Hg
分子名称: MERCURY (II) ION, Probable ATP-dependent RNA helicase DDX58
著者Cui, S, Lammens, A, Lammens, K, Hopfner, K.P.
登録日2007-06-27
公開日2008-02-12
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献The C-Terminal Regulatory Domain Is the RNA 5'-Triphosphate Sensor of RIG-I.
Mol.Cell, 29, 2008
5E3H
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BU of 5e3h by Molmil
Structural Basis for RNA Recognition and Activation of RIG-I
分子名称: ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, GLYCEROL, ...
著者Jiang, F, Miller, M.T, Marcotrigiano, J.
登録日2015-10-02
公開日2015-11-18
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structural basis of RNA recognition and activation by innate immune receptor RIG-I.
Nature, 479, 2011
4ON9
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BU of 4on9 by Molmil
DECH box helicase domain
分子名称: CHLORIDE ION, Probable ATP-dependent RNA helicase DDX58, SULFATE ION
著者Deimling, T, Witte, G, Hopfner, K.P.
登録日2014-01-28
公開日2014-07-02
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.71 Å)
主引用文献Crystal and solution structure of the human RIG-I SF2 domain
Acta Crystallogr.,Sect.F, 70, 2014
4AY2
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BU of 4ay2 by Molmil
Capturing 5' tri-phosphorylated RNA duplex by RIG-I
分子名称: 5'-R-PPP(GP*GP*CP*GP*CP*GP*GP*CP*UP*UP*CP*GP*GP*CP *CP*GP*CP*GP*CP*C)-3', ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ...
著者Luo, D, Pyle, A.M.
登録日2012-06-17
公開日2012-10-03
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Visualizing the Determinants of Viral RNA Recognition by Innate Immune Sensor Rig-I.
Structure, 20, 2012
3ZD6
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BU of 3zd6 by Molmil
Snapshot 1 of RIG-I scanning on RNA duplex
分子名称: PROBABLE ATP-DEPENDENT RNA HELICASE DDX58, RNA DUPLEX, ZINC ION
著者Luo, D, Pyle, A.M.
登録日2012-11-25
公開日2013-08-07
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Defining the Functional Determinants for RNA Surveillance by Rig-I.
Embo Rep., 14, 2013
6GPG
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BU of 6gpg by Molmil
Structure of the RIG-I Singleton-Merten syndrome variant C268F
分子名称: MAGNESIUM ION, Probable ATP-dependent RNA helicase DDX58, RNA (5'-R(*CP*GP*AP*CP*GP*CP*UP*AP*GP*CP*GP*UP*CP*G)-3'), ...
著者Laessig, C, Lammens, K, Hopfner, K.-P.
登録日2018-06-05
公開日2018-08-08
最終更新日2024-05-15
実験手法X-RAY DIFFRACTION (2.894 Å)
主引用文献Unified mechanisms for self-RNA recognition by RIG-I Singleton-Merten syndrome variants.
Elife, 7, 2018
8DVU
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BU of 8dvu by Molmil
Cryo-EM structure of RIG-I bound to the internal sites of OHSLR30 (+ATP)
分子名称: ADENOSINE-5'-DIPHOSPHATE, Antiviral innate immune response receptor RIG-I, MAGNESIUM ION, ...
著者Wang, W, Pyle, A.M.
登録日2022-07-29
公開日2022-11-16
最終更新日2024-06-12
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献The RIG-I receptor adopts two different conformations for distinguishing host from viral RNA ligands.
Mol.Cell, 82, 2022
6KYV
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BU of 6kyv by Molmil
Crystal Structure of RIG-I and hairpin RNA with G-U wobble base pairs
分子名称: Probable ATP-dependent RNA helicase DDX58, RNA (5'-R(*GP*GP*UP*AP*GP*AP*CP*GP*CP*UP*UP*CP*GP*GP*CP*GP*UP*UP*UP*GP*CP*C)-3'), ZINC ION
著者Kim, K.-H, Hwang, J, Kim, J.H, Son, K.-P, Jang, Y, Kim, M, Kang, S.-J, Lee, J.-O, Choi, B.-S.
登録日2019-09-20
公開日2020-09-23
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structural and biophysical properties of RIG-I bound to dsRNA with G-U wobble base pairs.
Rna Biol., 17, 2020
8DVS
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BU of 8dvs by Molmil
Cryo-EM structure of RIG-I bound to the end of OHSLR30 (+ATP)
分子名称: ADENOSINE-5'-DIPHOSPHATE, Antiviral innate immune response receptor RIG-I, MAGNESIUM ION, ...
著者Wang, W, Pyle, A.M.
登録日2022-07-29
公開日2022-11-16
最終更新日2024-06-12
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献The RIG-I receptor adopts two different conformations for distinguishing host from viral RNA ligands.
Mol.Cell, 82, 2022
2QFB
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BU of 2qfb by Molmil
Crystal structure of the regulatory domain of human RIG-I with bound Zn
分子名称: Probable ATP-dependent RNA helicase DDX58, ZINC ION
著者Cui, S, Lammens, A, Lammens, K, Hopfner, K.P.
登録日2007-06-27
公開日2008-02-12
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献The C-Terminal Regulatory Domain Is the RNA 5'-Triphosphate Sensor of RIG-I.
Mol.Cell, 29, 2008
5F9H
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BU of 5f9h by Molmil
Crystal structure of RIG-I helicase-RD in complex with 24-mer 5' triphosphate hairpin RNA
分子名称: GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Probable ATP-dependent RNA helicase DDX58, ...
著者Wang, C, Marcotrigiano, J, Miller, M, Jiang, F.
登録日2015-12-09
公開日2016-01-13
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Structural basis for m7G recognition and 2'-O-methyl discrimination in capped RNAs by the innate immune receptor RIG-I.
Proc.Natl.Acad.Sci.USA, 113, 2016
8G7T
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BU of 8g7t by Molmil
Cryo-EM structure of Riplet:RIG-I:dsRNA complex (end-end)
分子名称: Antiviral innate immune response receptor RIG-I, E3 ubiquitin-protein ligase RNF135, ZINC ION, ...
著者Wang, W, Pyle, A.M.
登録日2023-02-17
公開日2023-11-15
最終更新日2024-05-29
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献The E3 ligase Riplet promotes RIG-I signaling independent of RIG-I oligomerization.
Nat Commun, 14, 2023
7TNY
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BU of 7tny by Molmil
Cryo-EM structure of RIG-I in complex with p2dsRNA
分子名称: Antiviral innate immune response receptor RIG-I, ZINC ION, p2dsRNA
著者Wang, W, Pyle, A.M.
登録日2022-01-22
公開日2022-11-02
最終更新日2024-06-05
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献The RIG-I receptor adopts two different conformations for distinguishing host from viral RNA ligands.
Mol.Cell, 82, 2022
7TO2
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BU of 7to2 by Molmil
Cryo-EM structure of RIG-I bound to the internal sites of p3SLR30 (+ATP)
分子名称: ADENOSINE-5'-DIPHOSPHATE, Antiviral innate immune response receptor RIG-I, MAGNESIUM ION, ...
著者Wang, W, Pyle, A.M.
登録日2022-01-22
公開日2022-11-02
最終更新日2024-06-05
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献The RIG-I receptor adopts two different conformations for distinguishing host from viral RNA ligands.
Mol.Cell, 82, 2022
5F98
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BU of 5f98 by Molmil
Crystal structure of RIG-I in complex with Cap-0 RNA
分子名称: 7N-METHYL-8-HYDROGUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Probable ATP-dependent RNA helicase DDX58, ...
著者Wang, C, Marcotrigiano, J, Miller, M, Jiang, F.
登録日2015-12-09
公開日2016-01-13
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (3.28 Å)
主引用文献Structural basis for m7G recognition and 2'-O-methyl discrimination in capped RNAs by the innate immune receptor RIG-I.
Proc.Natl.Acad.Sci.USA, 113, 2016

 

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