3NCU

Structural and functional insights into pattern recognition by the innate immune receptor RIG-I

Summary for 3NCU

• Entry DOI: 10.2210/pdb3ncu/pdb
• Related: 2qfb 2rmj
• Descriptor: RIG-I, 5'-R(*(GDP)P*AP*CP*GP*CP*UP*AP*GP*CP*GP*UP*C)-3', ZINC ION, ... (4 entities in total)
• Functional Keywords: innate immune receptor, rig-i c-terminal domain, rna binding protein-rna complex, rna binding protein/rna
• Biological source: Homo sapiens (human)
• Cellular location: Cytoplasm: O95786
• Total number of polymer chains: 4
• Total formula weight: 39263.81

Authors

Sheng, G.,Li, H. (deposition date: 2010-06-05, release date: 2010-06-30, Last modification date: 2023-09-06)

• Primary citation: Wang, Y.,Ludwig, J.,Schuberth, C.,Goldeck, M.,Schlee, M.,Li, H.,Juranek, S.,Sheng, G.,Micura, R.,Tuschl, T.,Hartmann, G.,Patel, D.J.; Structural and functional insights into 5'-ppp RNA pattern recognition by the innate immune receptor RIG-I.; Nat.Struct.Mol.Biol., 17:781-787, 2010; PubMed: 20581823; DOI: 10.1038/nsmb.1863

Experimental method

X-RAY DIFFRACTION (2.55 Å)