2RMJ

Solution structure of RIG-I C-terminal domain

Summary for 2RMJ

Entry DOI	10.2210/pdb2rmj/pdb
Descriptor	Probable ATP-dependent RNA helicase DDX58 (1 entity in total)
Functional Keywords	rna binding protein, alternative splicing, antiviral defense, atp-binding, cytoplasm, helicase, hydrolase, immune response, innate immunity, interferon induction, nucleotide-binding, polymorphism, rna-binding, ubl conjugation
Biological source	Homo sapiens (human)
Cellular location	Cytoplasm: O95786
Total number of polymer chains	1
Total formula weight	15659.18
Authors	Takahasi, K.,Yoneyama, M.,Nihishori, T.,Hirai, R.,Narita, R.,Gale Jr., M.,Fujita, T.,Inagaki, F. (deposition date: 2007-10-23, release date: 2008-03-25, Last modification date: 2024-05-29)
Primary citation	Takahasi, K.,Yoneyama, M.,Nishihori, T.,Hirai, R.,Kumeta, H.,Narita, R.,Gale Jr., M.,Inagaki, F.,Fujita, T. Nonself RNA-Sensing Mechanism of RIG-I Helicase and Activation of Antiviral Immune Responses Mol.Cell, 29:428-440, 2008 Cited by PubMed: 18242112 DOI: 10.1016/j.molcel.2007.11.028 PDB entries with the same primary citation
Experimental method	SOLUTION NMR

Structure validation