6GPG

Structure of the RIG-I Singleton-Merten syndrome variant C268F

Summary for 6GPG

• Entry DOI: 10.2210/pdb6gpg/pdb
• Descriptor: RNA (5'-R(*CP*GP*AP*CP*GP*CP*UP*AP*GP*CP*GP*UP*CP*G)-3'), Probable ATP-dependent RNA helicase DDX58, ZINC ION, ... (4 entities in total)
• Functional Keywords: innate immune system, rig-i, singleton-merten syndrome, rna-dependent atpase, rna binding protein, antiviral protein
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 3
• Total formula weight: 90941.53

Authors

Laessig, C.,Lammens, K.,Hopfer, K.-P. (deposition date: 2018-06-05, release date: 2018-08-08)

• Primary citation: Lassig, C.,Lammens, K.,Gorenflos Lopez, J.L.,Michalski, S.,Fettscher, O.,Hopfner, K.P.; Unified mechanisms for self-RNA recognition by RIG-I Singleton-Merten syndrome variants.; Elife, 7:-, 2018; PubMed: 30047865; DOI: 10.7554/eLife.38958

Experimental method

X-RAY DIFFRACTION (2.894 Å)