6KYV

Crystal Structure of RIG-I and hairpin RNA with G-U wobble base pairs

Summary for 6KYV

• Entry DOI: 10.2210/pdb6kyv/pdb
• Descriptor: RNA (5'-R(*GP*GP*UP*AP*GP*AP*CP*GP*CP*UP*UP*CP*GP*GP*CP*GP*UP*UP*UP*GP*CP*C)-3'), Probable ATP-dependent RNA helicase DDX58, ZINC ION (3 entities in total)
• Functional Keywords: rig-i, ddx58, dsrna, wobble base pair, immune system
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 12
• Total formula weight: 512501.07

Authors

Kim, K.-H.,Hwang, J.,Kim, J.H.,Son, K.-P.,Jang, Y.,Kim, M.,Kang, S.-J.,Lee, J.-O.,Choi, B.-S. (deposition date: 2019-09-20, release date: 2020-09-23, Last modification date: 2023-11-22)

• Primary citation: Kim, K.H.,Hwang, J.,Kim, J.H.,Son, K.P.,Jang, Y.,Kim, M.,Kang, S.J.,Lee, J.O.,Kang, J.Y.,Choi, B.S.; Structural and biophysical properties of RIG-I bound to dsRNA with G-U wobble base pairs.; Rna Biol., 17:325-334, 2020; PubMed: 31852354; DOI: 10.1080/15476286.2019.1700034

Experimental method

X-RAY DIFFRACTION (3 Å)