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6KYV

Crystal Structure of RIG-I and hairpin RNA with G-U wobble base pairs

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, C, E, G, I...RNA (5'-R(*GP*GP*UP*AP*GP*AP*CP*GP*CP*UP*UP*CP*GP*GP*CP*GP*UP*UP*UP*GP*CP*C)-3')polymer227043.26synthetic construct
2B, D, F, H, J...Probable ATP-dependent RNA helicase DDX58polymer68478308.36UniProt (O95786)
Pfam (PF00270)
Pfam (PF18119)
Pfam (PF00271)
Pfam (PF11648)
In PDB
Homo sapiens (Human)DEAD box protein 58,RIG-I-like receptor 1,RLR-1,Retinoic acid-inducible gene 1 protein,RIG-1,Retinoic acid-inducible gene I protein,RIG-I
3B, D, F, H, J...ZINC IONnon-polymer65.46Chemie (ZN)
Sequence modifications
B, D, F, H, J, L: 242 - 922 (UniProt: O95786)
PDBExternal DatabaseDetails
Ser 239-expression tag
Asn 240-expression tag
Ala 241-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains12
Total formula weight512108.6
Non-Polymers*Number of molecules6
Total formula weight392.5
All*Total formula weight512501.1
*Water molecules are not included.

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PDB entries from 2024-05-15

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