6KYV

Crystal Structure of RIG-I and hairpin RNA with G-U wobble base pairs

Functional Information from GO Data

Chain	GOid	namespace	contents
B	0003676	molecular_function	nucleic acid binding
B	0005524	molecular_function	ATP binding
D	0003676	molecular_function	nucleic acid binding
D	0005524	molecular_function	ATP binding
F	0003676	molecular_function	nucleic acid binding
F	0005524	molecular_function	ATP binding
H	0003676	molecular_function	nucleic acid binding
H	0005524	molecular_function	ATP binding
J	0003676	molecular_function	nucleic acid binding
J	0005524	molecular_function	ATP binding
L	0003676	molecular_function	nucleic acid binding
L	0005524	molecular_function	ATP binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	binding site for residue ZN B 1001

Chain	Residue
B	CYS810
B	CYS813
B	CYS864
B	CYS869

---

site_id	AC2
Number of Residues	4
Details	binding site for residue ZN D 1001

Chain	Residue
D	CYS810
D	CYS813
D	CYS864
D	CYS869

---

site_id	AC3
Number of Residues	4
Details	binding site for residue ZN F 1001

Chain	Residue
F	CYS813
F	CYS864
F	CYS869
F	CYS810

---

site_id	AC4
Number of Residues	4
Details	binding site for residue ZN H 1001

Chain	Residue
H	CYS810
H	CYS813
H	CYS864
H	CYS869

---

site_id	AC5
Number of Residues	4
Details	binding site for residue ZN J 1001

Chain	Residue
J	CYS810
J	CYS813
J	CYS864
J	CYS869

---

site_id	AC6
Number of Residues	4
Details	binding site for residue ZN L 1001

Chain	Residue
L	CYS810
L	CYS813
L	CYS864
L	CYS869

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1074
Details	Domain: {"description":"Helicase ATP-binding","evidences":[{"source":"PROSITE-ProRule","id":"PRU00541","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	996
Details	Domain: {"description":"Helicase C-terminal","evidences":[{"source":"PROSITE-ProRule","id":"PRU00542","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	18
Details	Motif: {"description":"DECH box"}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	42
Details	Binding site: {"evidences":[{"evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	24
Details	Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU01125","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI6
Number of Residues	12
Details	Modified residue: {"description":"(Microbial infection) Deamidated asparagine; by herpes simplex virus 1/HHV-1 UL37","evidences":[{"source":"PubMed","id":"27866900","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI7
Number of Residues	6
Details	Modified residue: {"description":"Phosphothreonine; by CK2","evidences":[{"source":"PubMed","id":"21068236","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI8
Number of Residues	12
Details	Modified residue: {"description":"Phosphoserine; by CK2","evidences":[{"source":"PubMed","id":"21068236","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI9
Number of Residues	6
Details	Modified residue: {"description":"N6-acetyllysine","evidences":[{"source":"PubMed","id":"19608861","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI10
Number of Residues	6
Details	Modified residue: {"description":"N6-acetyllysine","evidences":[{"source":"PubMed","id":"26746851","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI11
Number of Residues	12
Details	Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin)","evidences":[{"source":"UniProtKB","id":"Q6Q899","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---