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2QFD

Crystal structure of the regulatory domain of human RIG-I with bound Hg

Summary for 2QFD
Entry DOI10.2210/pdb2qfd/pdb
Related2QFB
DescriptorProbable ATP-dependent RNA helicase DDX58, MERCURY (II) ION (3 entities in total)
Functional Keywordszinc finger, alternative splicing, antiviral defense, atp-binding, helicase, hydrolase, immune response, innate immunity, interferon induction, nucleotide-binding, polymorphism, rna-binding, ubl conjugation
Biological sourceHomo sapiens (human)
Cellular locationCytoplasm: O95786
Total number of polymer chains10
Total formula weight170540.88
Authors
Cui, S.,Lammens, A.,Lammens, K.,Hopfner, K.P. (deposition date: 2007-06-27, release date: 2008-02-12, Last modification date: 2011-07-13)
Primary citationCui, S.,Eisenacher, K.,Kirchhofer, A.,Brzozka, K.,Lammens, A.,Lammens, K.,Fujita, T.,Conzelmann, K.K.,Krug, A.,Hopfner, K.P.
The C-Terminal Regulatory Domain Is the RNA 5'-Triphosphate Sensor of RIG-I.
Mol.Cell, 29:169-179, 2008
Cited by
PubMed: 18243112
DOI: 10.1016/j.molcel.2007.10.032
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.7 Å)
Structure validation

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