2QFD

Crystal structure of the regulatory domain of human RIG-I with bound Hg

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D, E... (A, B, C, D, E...)	Probable ATP-dependent RNA helicase DDX58	polymer	145	16853.5	10	UniProt (O95786) Pfam (PF11648)	Homo sapiens (human)	DEAD-box protein 58, Retinoic acid-inducible gene 1 protein, RIG-1, RIG-I
2	K, L, M, N, O... (A, B, C, D, E...)	MERCURY (II) ION	non-polymer		200.6	10	Chemie (HG)
3	AA, BA, U, V, W... (G, H, A, B, C...)	water	water		18.0	102	Chemie (HOH)

Sequence modifications

A, B, C, D, E, F, G, H, I, J: 802 - 925 (UniProt: O95786)

PDB	External Database	Details
Met 781	-	expression tag
Gly 782	-	expression tag
Ser 783	-	expression tag
Ser 784	-	expression tag
His 785	-	expression tag
His 786	-	expression tag
His 787	-	expression tag
His 788	-	expression tag
His 789	-	expression tag
His 790	-	expression tag
Ser 791	-	expression tag
Ser 792	-	expression tag
Gly 793	-	expression tag
Leu 794	-	expression tag
Val 795	-	expression tag
Pro 796	-	expression tag
Arg 797	-	expression tag
Gly 798	-	expression tag
Ser 799	-	expression tag
His 800	-	expression tag
Met 801	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	10
	Total formula weight	168535.0
Non-Polymers*	Number of molecules	10
	Total formula weight	2005.9
All*	Total formula weight	170540.9

*Water molecules are not included.