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5E3H

Structural Basis for RNA Recognition and Activation of RIG-I

Replaces:  3TMI
Summary for 5E3H
Entry DOI10.2210/pdb5e3h/pdb
Related3TMI
DescriptorProbable ATP-dependent RNA helicase DDX58, RNA (5'-R(*CP*GP*AP*CP*GP*CP*UP*AP*GP*CP*GP*U)-3'), ZINC ION, ... (7 entities in total)
Functional Keywordsadenosine triphosphatases, adenosine triphosphate, dead-box rna helicases, enzyme activation, fluorometry, humans, immunity, innate, models, molecular, nucleic acid conformation, pliability, protein binding, protein structure, tertiary, proteolysis, rna, double-stranded, rna-binding proteins, scattering, small angle, structure-activity relationship, substrate specificity, trypsin, hydrolase, hydrolase-rna complex, hydrolase/rna
Biological sourceHomo sapiens (Human)
More
Total number of polymer chains3
Total formula weight89273.81
Authors
Jiang, F.,Miller, M.T.,Marcotrigiano, J. (deposition date: 2015-10-02, release date: 2015-11-18, Last modification date: 2023-09-27)
Primary citationJiang, F.,Ramanathan, A.,Miller, M.T.,Tang, G.Q.,Gale, M.,Patel, S.S.,Marcotrigiano, J.
Structural basis of RNA recognition and activation by innate immune receptor RIG-I.
Nature, 479:423-427, 2011
Cited by
PubMed: 21947008
DOI: 10.1038/nature10537
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.7 Å)
Structure validation

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