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5E3H

Structural Basis for RNA Recognition and Activation of RIG-I

Replaces:  3TMI
Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Probable ATP-dependent RNA helicase DDX58polymer69579594.71UniProt (O95786)
Pfam (PF00270)
Pfam (PF18119)
Pfam (PF00271)
Pfam (PF11648)
Homo sapiens (Human)DEAD box protein 58,RIG-I-like receptor 1,RLR-1,Retinoic acid-inducible gene 1 protein,RIG-1,Retinoic acid-inducible gene I protein,RIG-I
2B, C
(B, C)
RNA (5'-R(*CP*GP*AP*CP*GP*CP*UP*AP*GP*CP*GP*U)-3')polymer144477.72synthetic construct
3D
(A)
ZINC IONnon-polymer65.41Chemie (ZN)
4E, F, G
(A)
MAGNESIUM IONnon-polymer24.33Chemie (MG)
5H
(A)
GLYCEROLnon-polymer92.11Chemie (GOL)
6I
(A)
ADENOSINE-5'-DIPHOSPHATEnon-polymer427.21Chemie (ADP)
7J
(A)
BERYLLIUM TRIFLUORIDE IONnon-polymer66.01Chemie (BEF)
Sequence modifications
A: 232 - 925 (UniProt: O95786)
PDBExternal DatabaseDetails
Ser 231-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains3
Total formula weight88550.2
Non-Polymers*Number of molecules7
Total formula weight723.6
All*Total formula weight89273.8
*Water molecules are not included.

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PDB entries from 2025-06-18

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