4AY2

Capturing 5' tri-phosphorylated RNA duplex by RIG-I

Summary for 4AY2

• Entry DOI: 10.2210/pdb4ay2/pdb
• Related: 2YKG
• Descriptor: PROBABLE ATP-DEPENDENT RNA HELICASE DDX58, 5'-R-PPP(GP*GP*CP*GP*CP*GP*GP*CP*UP*UP*CP*GP*GP*CP *CP*GP*CP*GP*CP*C)-3', ZINC ION, ... (6 entities in total)
• Functional Keywords: hydrolase-rna complex, innate immunity, hydrolase/rna
• Biological source: HOMO SAPIENS (HUMAN)
• Cellular location: Cytoplasm: O95786
• Total number of polymer chains: 2
• Total formula weight: 85784.49

Authors

Luo, D.,Pyle, A.M. (deposition date: 2012-06-17, release date: 2012-10-03, Last modification date: 2023-12-20)

• Primary citation: Luo, D.,Kohlway, A.,Vela, A.,Pyle, A.M.; Visualizing the Determinants of Viral RNA Recognition by Innate Immune Sensor Rig-I.; Structure, 20:1983-, 2012; PubMed: 23022350; DOI: 10.1016/J.STR.2012.08.029

Experimental method

X-RAY DIFFRACTION (2.8 Å)